DAR - Bologna Biocomputing Group

Search summary (UniProt accession: Q9C000)

Number of enzymes:	1
Number of disease:	4
Number of reactomes:	1
Number of reactions:	4

Search results (UniProt accession: Q9C000)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0032925	NLRP1	Q9C000	3.4.-.- 3.6.4.-	R-HSA-844455 R-HSA-844455 Reactome Name: The NLRP1 inflammasome See in Reactome	R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-168643 R-HSA-168643 Reactome Name: Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-622312 R-HSA-622312 Reactome Name: Inflammasomes See in Reactome	Immune System	R-HSA-844438 ( R-HSA-844455 ) R-HSA-844438 Reaction Name: NLRP1 oligomerizes See in Reactome R-HSA-844447 ( R-HSA-844455 ) R-HSA-844447 Reaction Name: NLRP1 senses MDP See in Reactome R-HSA-879201 ( R-HSA-844455 ) R-HSA-879201 Reaction Name: Bcl-2 and Bcl-XL bind NLRP1 See in Reactome R-HSA-879222 ( R-HSA-844455 ) R-HSA-879222 Reaction Name: MDP:NLRP1 binds ATP See in Reactome
MONDO:0060457	NLRP1	Q9C000	3.4.-.- 3.6.4.-	R-HSA-844455 R-HSA-844455 Reactome Name: The NLRP1 inflammasome See in Reactome	R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-168643 R-HSA-168643 Reactome Name: Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-622312 R-HSA-622312 Reactome Name: Inflammasomes See in Reactome	Immune System	R-HSA-844438 ( R-HSA-844455 ) R-HSA-844438 Reaction Name: NLRP1 oligomerizes See in Reactome R-HSA-844447 ( R-HSA-844455 ) R-HSA-844447 Reaction Name: NLRP1 senses MDP See in Reactome R-HSA-879201 ( R-HSA-844455 ) R-HSA-879201 Reaction Name: Bcl-2 and Bcl-XL bind NLRP1 See in Reactome R-HSA-879222 ( R-HSA-844455 ) R-HSA-879222 Reaction Name: MDP:NLRP1 binds ATP See in Reactome
MONDO:0011684	NLRP1	Q9C000	3.4.-.- 3.6.4.-	R-HSA-844455 R-HSA-844455 Reactome Name: The NLRP1 inflammasome See in Reactome	R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-168643 R-HSA-168643 Reactome Name: Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-622312 R-HSA-622312 Reactome Name: Inflammasomes See in Reactome	Immune System	R-HSA-844438 ( R-HSA-844455 ) R-HSA-844438 Reaction Name: NLRP1 oligomerizes See in Reactome R-HSA-844447 ( R-HSA-844455 ) R-HSA-844447 Reaction Name: NLRP1 senses MDP See in Reactome R-HSA-879201 ( R-HSA-844455 ) R-HSA-879201 Reaction Name: Bcl-2 and Bcl-XL bind NLRP1 See in Reactome R-HSA-879222 ( R-HSA-844455 ) R-HSA-879222 Reaction Name: MDP:NLRP1 binds ATP See in Reactome
MONDO:0014089	NLRP1	Q9C000	3.4.-.- 3.6.4.-	R-HSA-844455 R-HSA-844455 Reactome Name: The NLRP1 inflammasome See in Reactome	R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-168643 R-HSA-168643 Reactome Name: Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-622312 R-HSA-622312 Reactome Name: Inflammasomes See in Reactome	Immune System	R-HSA-844438 ( R-HSA-844455 ) R-HSA-844438 Reaction Name: NLRP1 oligomerizes See in Reactome R-HSA-844447 ( R-HSA-844455 ) R-HSA-844447 Reaction Name: NLRP1 senses MDP See in Reactome R-HSA-879201 ( R-HSA-844455 ) R-HSA-879201 Reaction Name: Bcl-2 and Bcl-XL bind NLRP1 See in Reactome R-HSA-879222 ( R-HSA-844455 ) R-HSA-879222 Reaction Name: MDP:NLRP1 binds ATP See in Reactome