DAR - Bologna Biocomputing Group

Search summary (UniProt accession: Q92560)

Number of enzymes:	1
Number of disease:	6
Number of reactomes:	2
Number of reactions:	8

Search results (UniProt accession: Q92560)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0019438	BAP1	Q92560	3.4.19.12	R-HSA-5693565 R-HSA-5693565 Reactome Name: Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks See in Reactome R-HSA-5689603 R-HSA-5689603 Reactome Name: UCH proteinases See in Reactome	R-HSA-5688426 R-HSA-5688426 Reactome Name: Deubiquitination See in Reactome R-HSA-5693606 R-HSA-5693606 Reactome Name: DNA Double Strand Break Response See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-73894 R-HSA-73894 Reactome Name: DNA Repair See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome R-HSA-5693532 R-HSA-5693532 Reactome Name: DNA Double-Strand Break Repair See in Reactome	Metabolism of proteins DNA Repair	R-HSA-5689630 ( R-HSA-5689603 ) R-HSA-5689630 Reaction Name: BAP1 binds BAP1-interacting complex See in Reactome R-HSA-5689649 ( R-HSA-5689603 ) R-HSA-5689649 Reaction Name: BAP1 binds BRCA1:BARD1 See in Reactome R-HSA-5690759 ( R-HSA-5689603 ) R-HSA-5690759 Reaction Name: BAP1:Ub-HCFC1 deubiquitinates BAP1:Ub-HCFC1 See in Reactome R-HSA-5690785 ( R-HSA-5689603 ) R-HSA-5690785 Reaction Name: BAP1 binds Ub-HCFC1 See in Reactome R-HSA-5690790 ( R-HSA-5689603 ) R-HSA-5690790 Reaction Name: Histone H2A is dubiquitinated by the PR-DUB complex See in Reactome R-HSA-9700998 ( R-HSA-5693565 ) R-HSA-9700998 Reaction Name: BAP1 disrupts the BRCA1:BARD1 heterodimer See in Reactome R-HSA-9701000 ( R-HSA-5693565 ) R-HSA-9701000 Reaction Name: BRCA1:BARD1 heterodimer autoubiquitinates See in Reactome R-HSA-9701003 ( R-HSA-5693565 ) R-HSA-9701003 Reaction Name: BAP1 binds BRCA1:BARD1 heterodimer See in Reactome
MONDO:0009693	BAP1	Q92560	3.4.19.12	R-HSA-5693565 R-HSA-5693565 Reactome Name: Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks See in Reactome R-HSA-5689603 R-HSA-5689603 Reactome Name: UCH proteinases See in Reactome	R-HSA-5688426 R-HSA-5688426 Reactome Name: Deubiquitination See in Reactome R-HSA-5693606 R-HSA-5693606 Reactome Name: DNA Double Strand Break Response See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-73894 R-HSA-73894 Reactome Name: DNA Repair See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome R-HSA-5693532 R-HSA-5693532 Reactome Name: DNA Double-Strand Break Repair See in Reactome	Metabolism of proteins DNA Repair	R-HSA-5689630 ( R-HSA-5689603 ) R-HSA-5689630 Reaction Name: BAP1 binds BAP1-interacting complex See in Reactome R-HSA-5689649 ( R-HSA-5689603 ) R-HSA-5689649 Reaction Name: BAP1 binds BRCA1:BARD1 See in Reactome R-HSA-5690759 ( R-HSA-5689603 ) R-HSA-5690759 Reaction Name: BAP1:Ub-HCFC1 deubiquitinates BAP1:Ub-HCFC1 See in Reactome R-HSA-5690785 ( R-HSA-5689603 ) R-HSA-5690785 Reaction Name: BAP1 binds Ub-HCFC1 See in Reactome R-HSA-5690790 ( R-HSA-5689603 ) R-HSA-5690790 Reaction Name: Histone H2A is dubiquitinated by the PR-DUB complex See in Reactome R-HSA-9700998 ( R-HSA-5693565 ) R-HSA-9700998 Reaction Name: BAP1 disrupts the BRCA1:BARD1 heterodimer See in Reactome R-HSA-9701000 ( R-HSA-5693565 ) R-HSA-9701000 Reaction Name: BRCA1:BARD1 heterodimer autoubiquitinates See in Reactome R-HSA-9701003 ( R-HSA-5693565 ) R-HSA-9701003 Reaction Name: BAP1 binds BRCA1:BARD1 heterodimer See in Reactome
MONDO:0006292	BAP1	Q92560	3.4.19.12	R-HSA-5693565 R-HSA-5693565 Reactome Name: Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks See in Reactome R-HSA-5689603 R-HSA-5689603 Reactome Name: UCH proteinases See in Reactome	R-HSA-5688426 R-HSA-5688426 Reactome Name: Deubiquitination See in Reactome R-HSA-5693606 R-HSA-5693606 Reactome Name: DNA Double Strand Break Response See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-73894 R-HSA-73894 Reactome Name: DNA Repair See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome R-HSA-5693532 R-HSA-5693532 Reactome Name: DNA Double-Strand Break Repair See in Reactome	Metabolism of proteins DNA Repair	R-HSA-5689630 ( R-HSA-5689603 ) R-HSA-5689630 Reaction Name: BAP1 binds BAP1-interacting complex See in Reactome R-HSA-5689649 ( R-HSA-5689603 ) R-HSA-5689649 Reaction Name: BAP1 binds BRCA1:BARD1 See in Reactome R-HSA-5690759 ( R-HSA-5689603 ) R-HSA-5690759 Reaction Name: BAP1:Ub-HCFC1 deubiquitinates BAP1:Ub-HCFC1 See in Reactome R-HSA-5690785 ( R-HSA-5689603 ) R-HSA-5690785 Reaction Name: BAP1 binds Ub-HCFC1 See in Reactome R-HSA-5690790 ( R-HSA-5689603 ) R-HSA-5690790 Reaction Name: Histone H2A is dubiquitinated by the PR-DUB complex See in Reactome R-HSA-9700998 ( R-HSA-5693565 ) R-HSA-9700998 Reaction Name: BAP1 disrupts the BRCA1:BARD1 heterodimer See in Reactome R-HSA-9701000 ( R-HSA-5693565 ) R-HSA-9701000 Reaction Name: BRCA1:BARD1 heterodimer autoubiquitinates See in Reactome R-HSA-9701003 ( R-HSA-5693565 ) R-HSA-9701003 Reaction Name: BAP1 binds BRCA1:BARD1 heterodimer See in Reactome
MONDO:0013692	BAP1	Q92560	3.4.19.12	R-HSA-5693565 R-HSA-5693565 Reactome Name: Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks See in Reactome R-HSA-5689603 R-HSA-5689603 Reactome Name: UCH proteinases See in Reactome	R-HSA-5688426 R-HSA-5688426 Reactome Name: Deubiquitination See in Reactome R-HSA-5693606 R-HSA-5693606 Reactome Name: DNA Double Strand Break Response See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-73894 R-HSA-73894 Reactome Name: DNA Repair See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome R-HSA-5693532 R-HSA-5693532 Reactome Name: DNA Double-Strand Break Repair See in Reactome	Metabolism of proteins DNA Repair	R-HSA-5689630 ( R-HSA-5689603 ) R-HSA-5689630 Reaction Name: BAP1 binds BAP1-interacting complex See in Reactome R-HSA-5689649 ( R-HSA-5689603 ) R-HSA-5689649 Reaction Name: BAP1 binds BRCA1:BARD1 See in Reactome R-HSA-5690759 ( R-HSA-5689603 ) R-HSA-5690759 Reaction Name: BAP1:Ub-HCFC1 deubiquitinates BAP1:Ub-HCFC1 See in Reactome R-HSA-5690785 ( R-HSA-5689603 ) R-HSA-5690785 Reaction Name: BAP1 binds Ub-HCFC1 See in Reactome R-HSA-5690790 ( R-HSA-5689603 ) R-HSA-5690790 Reaction Name: Histone H2A is dubiquitinated by the PR-DUB complex See in Reactome R-HSA-9700998 ( R-HSA-5693565 ) R-HSA-9700998 Reaction Name: BAP1 disrupts the BRCA1:BARD1 heterodimer See in Reactome R-HSA-9701000 ( R-HSA-5693565 ) R-HSA-9701000 Reaction Name: BRCA1:BARD1 heterodimer autoubiquitinates See in Reactome R-HSA-9701003 ( R-HSA-5693565 ) R-HSA-9701003 Reaction Name: BAP1 binds BRCA1:BARD1 heterodimer See in Reactome
MONDO:0016642	BAP1	Q92560	3.4.19.12	R-HSA-5693565 R-HSA-5693565 Reactome Name: Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks See in Reactome R-HSA-5689603 R-HSA-5689603 Reactome Name: UCH proteinases See in Reactome	R-HSA-5688426 R-HSA-5688426 Reactome Name: Deubiquitination See in Reactome R-HSA-5693606 R-HSA-5693606 Reactome Name: DNA Double Strand Break Response See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-73894 R-HSA-73894 Reactome Name: DNA Repair See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome R-HSA-5693532 R-HSA-5693532 Reactome Name: DNA Double-Strand Break Repair See in Reactome	Metabolism of proteins DNA Repair	R-HSA-5689630 ( R-HSA-5689603 ) R-HSA-5689630 Reaction Name: BAP1 binds BAP1-interacting complex See in Reactome R-HSA-5689649 ( R-HSA-5689603 ) R-HSA-5689649 Reaction Name: BAP1 binds BRCA1:BARD1 See in Reactome R-HSA-5690759 ( R-HSA-5689603 ) R-HSA-5690759 Reaction Name: BAP1:Ub-HCFC1 deubiquitinates BAP1:Ub-HCFC1 See in Reactome R-HSA-5690785 ( R-HSA-5689603 ) R-HSA-5690785 Reaction Name: BAP1 binds Ub-HCFC1 See in Reactome R-HSA-5690790 ( R-HSA-5689603 ) R-HSA-5690790 Reaction Name: Histone H2A is dubiquitinated by the PR-DUB complex See in Reactome R-HSA-9700998 ( R-HSA-5693565 ) R-HSA-9700998 Reaction Name: BAP1 disrupts the BRCA1:BARD1 heterodimer See in Reactome R-HSA-9701000 ( R-HSA-5693565 ) R-HSA-9701000 Reaction Name: BRCA1:BARD1 heterodimer autoubiquitinates See in Reactome R-HSA-9701003 ( R-HSA-5693565 ) R-HSA-9701003 Reaction Name: BAP1 binds BRCA1:BARD1 heterodimer See in Reactome
MONDO:0006486	BAP1	Q92560	3.4.19.12	R-HSA-5693565 R-HSA-5693565 Reactome Name: Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks See in Reactome R-HSA-5689603 R-HSA-5689603 Reactome Name: UCH proteinases See in Reactome	R-HSA-5688426 R-HSA-5688426 Reactome Name: Deubiquitination See in Reactome R-HSA-5693606 R-HSA-5693606 Reactome Name: DNA Double Strand Break Response See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-73894 R-HSA-73894 Reactome Name: DNA Repair See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome R-HSA-5693532 R-HSA-5693532 Reactome Name: DNA Double-Strand Break Repair See in Reactome	Metabolism of proteins DNA Repair	R-HSA-5689630 ( R-HSA-5689603 ) R-HSA-5689630 Reaction Name: BAP1 binds BAP1-interacting complex See in Reactome R-HSA-5689649 ( R-HSA-5689603 ) R-HSA-5689649 Reaction Name: BAP1 binds BRCA1:BARD1 See in Reactome R-HSA-5690759 ( R-HSA-5689603 ) R-HSA-5690759 Reaction Name: BAP1:Ub-HCFC1 deubiquitinates BAP1:Ub-HCFC1 See in Reactome R-HSA-5690785 ( R-HSA-5689603 ) R-HSA-5690785 Reaction Name: BAP1 binds Ub-HCFC1 See in Reactome R-HSA-5690790 ( R-HSA-5689603 ) R-HSA-5690790 Reaction Name: Histone H2A is dubiquitinated by the PR-DUB complex See in Reactome R-HSA-9700998 ( R-HSA-5693565 ) R-HSA-9700998 Reaction Name: BAP1 disrupts the BRCA1:BARD1 heterodimer See in Reactome R-HSA-9701000 ( R-HSA-5693565 ) R-HSA-9701000 Reaction Name: BRCA1:BARD1 heterodimer autoubiquitinates See in Reactome R-HSA-9701003 ( R-HSA-5693565 ) R-HSA-9701003 Reaction Name: BAP1 binds BRCA1:BARD1 heterodimer See in Reactome