DAR - Bologna Biocomputing Group

Search summary (UniProt accession: Q8NDG6)

Number of enzymes:	1
Number of disease:	2
Number of reactomes:	1
Number of reactions:	4

Search results (UniProt accession: Q8NDG6)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0020851	TDRD9	Q8NDG6	3.6.4.13	R-HSA-5601884 R-HSA-5601884 Reactome Name: PIWI-interacting RNA (piRNA) biogenesis See in Reactome	R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-211000 R-HSA-211000 Reactome Name: Gene Silencing by RNA See in Reactome	Gene expression (Transcription)	R-HSA-5601883 ( R-HSA-5601884 ) R-HSA-5601883 Reaction Name: Complexed PIWIL4 binds cleaved transposon RNA See in Reactome R-HSA-5601897 ( R-HSA-5601884 ) R-HSA-5601897 Reaction Name: MeR-PIWIL4:2'-O-methyl-piRNA:TDRD9:MAEL:TDRKH dissociates and MeR-PIWIL4:2'-O-methylpiRNA, TDRD9, MAEL translocate from cytosol to nucleus in an unknown association and order of events See in Reactome R-HSA-5601919 ( R-HSA-5601884 ) R-HSA-5601919 Reaction Name: Unknown nuclease cleaves cleaved transposon RNA bound in MeR-PIWIL4:cleaved transposon RNA:TDRD9:MAEL:TDRKH See in Reactome R-HSA-5629237 ( R-HSA-5601884 ) R-HSA-5629237 Reaction Name: HENMT1 methylates 2' hydroxyl at 3' end of piRNA in MeR-PIWIL4:piRNA:TDRD9:MAEL:TDRKH See in Reactome
MONDO:0018393	TDRD9	Q8NDG6	3.6.4.13	R-HSA-5601884 R-HSA-5601884 Reactome Name: PIWI-interacting RNA (piRNA) biogenesis See in Reactome	R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-211000 R-HSA-211000 Reactome Name: Gene Silencing by RNA See in Reactome	Gene expression (Transcription)	R-HSA-5601883 ( R-HSA-5601884 ) R-HSA-5601883 Reaction Name: Complexed PIWIL4 binds cleaved transposon RNA See in Reactome R-HSA-5601897 ( R-HSA-5601884 ) R-HSA-5601897 Reaction Name: MeR-PIWIL4:2'-O-methyl-piRNA:TDRD9:MAEL:TDRKH dissociates and MeR-PIWIL4:2'-O-methylpiRNA, TDRD9, MAEL translocate from cytosol to nucleus in an unknown association and order of events See in Reactome R-HSA-5601919 ( R-HSA-5601884 ) R-HSA-5601919 Reaction Name: Unknown nuclease cleaves cleaved transposon RNA bound in MeR-PIWIL4:cleaved transposon RNA:TDRD9:MAEL:TDRKH See in Reactome R-HSA-5629237 ( R-HSA-5601884 ) R-HSA-5629237 Reaction Name: HENMT1 methylates 2' hydroxyl at 3' end of piRNA in MeR-PIWIL4:piRNA:TDRD9:MAEL:TDRKH See in Reactome