DAR - Bologna Biocomputing Group

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0010088	SUMF1	Q8NBK3	1.8.3.7	R-HSA-1660662 R-HSA-1660662 Reactome Name: Glycosphingolipid metabolism See in Reactome R-HSA-1663150 R-HSA-1663150 Reactome Name: The activation of arylsulfatases See in Reactome	R-HSA-163841 R-HSA-163841 Reactome Name: Gamma carboxylation, hypusine formation and arylsulfatase activation See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-428157 R-HSA-428157 Reactome Name: Sphingolipid metabolism See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome	Metabolism of proteins Metabolism	R-HSA-1614336 ( R-HSA-1660662; R-HSA-1663150 ) R-HSA-1614336 Reaction Name: SUMF2 binds SUMF1, inhibiting SUMF1-mediated activation of arylsulfatases See in Reactome R-HSA-1614362 ( R-HSA-1660662; R-HSA-1663150 ) R-HSA-1614362 Reaction Name: SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases See in Reactome