DAR - Bologna Biocomputing Group

Search summary (UniProt accession: Q8IU80)

Number of enzymes:	1
Number of disease:	1
Number of reactomes:	2
Number of reactions:	9

Search results (UniProt accession: Q8IU80)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0008788	TMPRSS6	Q8IU80	3.4.21.-	R-HSA-1474228 R-HSA-1474228 Reactome Name: Degradation of the extracellular matrix See in Reactome R-HSA-1442490 R-HSA-1442490 Reactome Name: Collagen degradation See in Reactome	R-HSA-1474244 R-HSA-1474244 Reactome Name: Extracellular matrix organization See in Reactome	Extracellular matrix organization	R-HSA-1458433 ( R-HSA-1442490; R-HSA-1474228 ) R-HSA-1458433 Reaction Name: Collagen type I degradation by MMP14 See in Reactome R-HSA-1474196 ( R-HSA-1442490; R-HSA-1474228 ) R-HSA-1474196 Reaction Name: Collagen type II degradation by MMP14 See in Reactome R-HSA-1474210 ( R-HSA-1442490; R-HSA-1474228 ) R-HSA-1474210 Reaction Name: Collagen type III degradation by MMP14 See in Reactome R-HSA-2514790 ( R-HSA-1474228 ) R-HSA-2514790 Reaction Name: Elastin degradation by MMP14 See in Reactome R-HSA-2514831 ( R-HSA-1474228 ) R-HSA-2514831 Reaction Name: Fibrillin-1 degradation by MMP14 See in Reactome R-HSA-2533874 ( R-HSA-1474228 ) R-HSA-2533874 Reaction Name: Laminin-511 degradation by MMP14 See in Reactome R-HSA-2533950 ( R-HSA-1474228 ) R-HSA-2533950 Reaction Name: Fibronectin degradation by MMP14, TMPRSS6 See in Reactome R-HSA-3791155 ( R-HSA-1474228 ) R-HSA-3791155 Reaction Name: Laminin-322 degradation by MMP14 See in Reactome R-HSA-3828025 ( R-HSA-1474228 ) R-HSA-3828025 Reaction Name: DCN (decorin) degradation by MMP14 See in Reactome