DAR - Bologna Biocomputing Group

Search summary (UniProt accession: Q16394)

Number of enzymes:	1
Number of disease:	3
Number of reactomes:	1
Number of reactions:	4

Search results (UniProt accession: Q16394)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0007585	EXT1	Q16394	2.4.1.224 2.4.1.225	R-HSA-2022928 R-HSA-2022928 Reactome Name: HS-GAG biosynthesis See in Reactome	R-HSA-1630316 R-HSA-1630316 Reactome Name: Glycosaminoglycan metabolism See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-1638091 R-HSA-1638091 Reactome Name: Heparan sulfate/heparin (HS-GAG) metabolism See in Reactome R-HSA-71387 R-HSA-71387 Reactome Name: Metabolism of carbohydrates See in Reactome	Metabolism	R-HSA-2022851 ( R-HSA-2022928 ) R-HSA-2022851 Reaction Name: EXT1:EXT2 transfer GlcNAc to the heparan chain See in Reactome R-HSA-2022856 ( R-HSA-2022928 ) R-HSA-2022856 Reaction Name: EXT1:EXT2 transfers GlcNAc to heparan See in Reactome R-HSA-2022919 ( R-HSA-2022928 ) R-HSA-2022919 Reaction Name: EXT1:EXT2 transfers GlcNAc to the terminal GlcA residue See in Reactome R-HSA-2076392 ( R-HSA-2022928 ) R-HSA-2076392 Reaction Name: EXT1:EXT2 transfers GlcA to heparan See in Reactome
MONDO:0008977	EXT1	Q16394	2.4.1.224 2.4.1.225	R-HSA-2022928 R-HSA-2022928 Reactome Name: HS-GAG biosynthesis See in Reactome	R-HSA-1630316 R-HSA-1630316 Reactome Name: Glycosaminoglycan metabolism See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-1638091 R-HSA-1638091 Reactome Name: Heparan sulfate/heparin (HS-GAG) metabolism See in Reactome R-HSA-71387 R-HSA-71387 Reactome Name: Metabolism of carbohydrates See in Reactome	Metabolism	R-HSA-2022851 ( R-HSA-2022928 ) R-HSA-2022851 Reaction Name: EXT1:EXT2 transfer GlcNAc to the heparan chain See in Reactome R-HSA-2022856 ( R-HSA-2022928 ) R-HSA-2022856 Reaction Name: EXT1:EXT2 transfers GlcNAc to heparan See in Reactome R-HSA-2022919 ( R-HSA-2022928 ) R-HSA-2022919 Reaction Name: EXT1:EXT2 transfers GlcNAc to the terminal GlcA residue See in Reactome R-HSA-2076392 ( R-HSA-2022928 ) R-HSA-2076392 Reaction Name: EXT1:EXT2 transfers GlcA to heparan See in Reactome
MONDO:0007874	EXT1	Q16394	2.4.1.224 2.4.1.225	R-HSA-2022928 R-HSA-2022928 Reactome Name: HS-GAG biosynthesis See in Reactome	R-HSA-1630316 R-HSA-1630316 Reactome Name: Glycosaminoglycan metabolism See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-1638091 R-HSA-1638091 Reactome Name: Heparan sulfate/heparin (HS-GAG) metabolism See in Reactome R-HSA-71387 R-HSA-71387 Reactome Name: Metabolism of carbohydrates See in Reactome	Metabolism	R-HSA-2022851 ( R-HSA-2022928 ) R-HSA-2022851 Reaction Name: EXT1:EXT2 transfer GlcNAc to the heparan chain See in Reactome R-HSA-2022856 ( R-HSA-2022928 ) R-HSA-2022856 Reaction Name: EXT1:EXT2 transfers GlcNAc to heparan See in Reactome R-HSA-2022919 ( R-HSA-2022928 ) R-HSA-2022919 Reaction Name: EXT1:EXT2 transfers GlcNAc to the terminal GlcA residue See in Reactome R-HSA-2076392 ( R-HSA-2022928 ) R-HSA-2076392 Reaction Name: EXT1:EXT2 transfers GlcA to heparan See in Reactome