DAR - Bologna Biocomputing Group

Search summary (UniProt accession: Q08881)

Number of enzymes:	1
Number of disease:	1
Number of reactomes:	2
Number of reactions:	7

Search results (UniProt accession: Q08881)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0013081	ITK	Q08881	2.7.10.2	R-HSA-202433 R-HSA-202433 Reactome Name: Generation of second messenger molecules See in Reactome R-HSA-2871809 R-HSA-2871809 Reactome Name: FCERI mediated Ca+2 mobilization See in Reactome	R-HSA-2454202 R-HSA-2454202 Reactome Name: Fc epsilon receptor (FCERI) signaling See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-1280218 R-HSA-1280218 Reactome Name: Adaptive Immune System See in Reactome R-HSA-202403 R-HSA-202403 Reactome Name: TCR signaling See in Reactome	Immune System	R-HSA-202248 ( R-HSA-202433 ) R-HSA-202248 Reaction Name: Phosphorylation of PLC-gamma1 See in Reactome R-HSA-202375 ( R-HSA-202433 ) R-HSA-202375 Reaction Name: Recruitment of ITK to SLP-76 See in Reactome R-HSA-2730833 ( R-HSA-2871809 ) R-HSA-2730833 Reaction Name: Phosphorylation of TEC kinases by p-SYK See in Reactome R-HSA-2730847 ( R-HSA-2871809 ) R-HSA-2730847 Reaction Name: Hydrolysis of PIP2 by PLCG See in Reactome R-HSA-2730858 ( R-HSA-2871809 ) R-HSA-2730858 Reaction Name: Autophosphorylation of BTK/ITK See in Reactome R-HSA-2730885 ( R-HSA-2871809 ) R-HSA-2730885 Reaction Name: Recruitment of TEC kinases to p-SLP-76 See in Reactome R-HSA-2730888 ( R-HSA-2871809 ) R-HSA-2730888 Reaction Name: Phosphorylation of PLC-gamma See in Reactome