DAR - Bologna Biocomputing Group

Search summary (UniProt accession: Q06830)

Number of enzymes:	1
Number of disease:	1
Number of reactomes:	2
Number of reactions:	5

Search results (UniProt accession: Q06830)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0010184	PRDX1	Q06830	1.11.1.24	R-HSA-5628897 R-HSA-5628897 Reactome Name: TP53 Regulates Metabolic Genes See in Reactome R-HSA-3299685 R-HSA-3299685 Reactome Name: Detoxification of Reactive Oxygen Species See in Reactome	R-HSA-3700989 R-HSA-3700989 Reactome Name: Transcriptional Regulation by TP53 See in Reactome R-HSA-8953897 R-HSA-8953897 Reactome Name: Cellular responses to stimuli See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-2262752 R-HSA-2262752 Reactome Name: Cellular responses to stress See in Reactome R-HSA-9711123 R-HSA-9711123 Reactome Name: Cellular response to chemical stress See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome	Cellular responses to stimuli Gene expression (Transcription)	R-HSA-3341343 ( R-HSA-3299685; R-HSA-5628897 ) R-HSA-3341343 Reaction Name: PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O See in Reactome R-HSA-5631885 ( R-HSA-5628897 ) R-HSA-5631885 Reaction Name: PRDX1 overoxidizes See in Reactome R-HSA-5631903 ( R-HSA-5628897 ) R-HSA-5631903 Reaction Name: SESN1,2,3 bind overoxidized PRDX1 See in Reactome R-HSA-9759189 () R-HSA-9759189 Reaction Name: NFE2L2-dependent PRDX1 gene expression See in Reactome R-HSA-9760094 () R-HSA-9760094 Reaction Name: SRXN1 reduces hyperoxidized PRDX1 dimer See in Reactome