DAR - Bologna Biocomputing Group

Search summary (UniProt accession: Q05469)

Number of enzymes:	1
Number of disease:	1
Number of reactomes:	1
Number of reactions:	8

Search results (UniProt accession: Q05469)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0014431	LIPE	Q05469	3.1.1.23 3.1.1.79	R-HSA-163560 R-HSA-163560 Reactome Name: Triglyceride catabolism See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8979227 R-HSA-8979227 Reactome Name: Triglyceride metabolism See in Reactome	Metabolism	R-HSA-163402 ( R-HSA-163560 ) R-HSA-163402 Reaction Name: diacylglycerol + H2O -> 2-acylglycerol + fatty acid See in Reactome R-HSA-163416 ( R-HSA-163560 ) R-HSA-163416 Reaction Name: hormone-sensitive lipase (HSL) + 2 ATP -> phosphorylated HSL + 2 ADP See in Reactome R-HSA-163432 ( R-HSA-163560 ) R-HSA-163432 Reaction Name: cholesterol ester + H2O -> cholesterol + fatty acid See in Reactome R-HSA-163489 ( R-HSA-163560 ) R-HSA-163489 Reaction Name: phosphorylated HSL + H2O -> HSL + orthophosphate See in Reactome R-HSA-163549 ( R-HSA-163560 ) R-HSA-163549 Reaction Name: phosphorylated HSL dimer + FABP4 -> phosphorylated HSL dimer:FABP4 complex See in Reactome R-HSA-163551 ( R-HSA-163560 ) R-HSA-163551 Reaction Name: triacylglycerol + H2O -> diacylglycerol + fatty acid See in Reactome R-HSA-163554 ( R-HSA-163560 ) R-HSA-163554 Reaction Name: Phosphorylated HSL dimer translocates from the cytosol to the lipid particle See in Reactome R-HSA-163602 ( R-HSA-163560 ) R-HSA-163602 Reaction Name: 2 phosphorylated HSL monomers -> phosphorylated HSL dimer See in Reactome