DAR - Bologna Biocomputing Group

Search summary (UniProt accession: Q03518)

Number of enzymes:	1
Number of disease:	1
Number of reactomes:	2
Number of reactions:	8

Search results (UniProt accession: Q03518)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0011476	TAP1	Q03518	7.4.2.-	R-HSA-983170 R-HSA-983170 Reactome Name: Antigen Presentation: Folding, assembly and peptide loading of class I MHC See in Reactome R-HSA-1236974 R-HSA-1236974 Reactome Name: ER-Phagosome pathway See in Reactome	R-HSA-1236975 R-HSA-1236975 Reactome Name: Antigen processing-Cross presentation See in Reactome R-HSA-983169 R-HSA-983169 Reactome Name: Class I MHC mediated antigen processing & presentation See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-1280218 R-HSA-1280218 Reactome Name: Adaptive Immune System See in Reactome	Immune System	R-HSA-1236949 ( R-HSA-1236974 ) R-HSA-1236949 Reaction Name: Translocation of antigenic peptides back to phagosomes via TAP See in Reactome R-HSA-8863858 ( R-HSA-1236974 ) R-HSA-8863858 Reaction Name: SEC22B, CALR, STX4, TAP and TAPBP bind See in Reactome R-HSA-8863914 ( R-HSA-1236974 ) R-HSA-8863914 Reaction Name: Transport of SEC22B, TAP and PLC from ER to ERGIC See in Reactome R-HSA-8951499 ( R-HSA-983170 ) R-HSA-8951499 Reaction Name: Loading of antigenic peptides on to class I MHC See in Reactome R-HSA-8951595 ( R-HSA-1236974 ) R-HSA-8951595 Reaction Name: CALR, TAP, TAPBP dissociate from SEC22B:STX4 See in Reactome R-HSA-983142 ( R-HSA-983170 ) R-HSA-983142 Reaction Name: Formation of peptide loading complex (PLC) See in Reactome R-HSA-983144 ( R-HSA-983170 ) R-HSA-983144 Reaction Name: Transport of Antigen peptide in to ER See in Reactome R-HSA-983161 ( R-HSA-983170 ) R-HSA-983161 Reaction Name: Dissociation of the Antigenic peptide:MHC:B2M peptide loading complex See in Reactome