DAR - Bologna Biocomputing Group

Search summary (UniProt accession: Q02763)

Number of enzymes:	1
Number of disease:	3
Number of reactomes:	2
Number of reactions:	15

Search results (UniProt accession: Q02763)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0007203	TEK	Q02763	2.7.10.1	R-HSA-210993 R-HSA-210993 Reactome Name: Tie2 Signaling See in Reactome R-HSA-5673001 R-HSA-5673001 Reactome Name: RAF/MAP kinase cascade See in Reactome	R-HSA-109582 R-HSA-109582 Reactome Name: Hemostasis See in Reactome R-HSA-5684996 R-HSA-5684996 Reactome Name: MAPK1/MAPK3 signaling See in Reactome R-HSA-5683057 R-HSA-5683057 Reactome Name: MAPK family signaling cascades See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-202733 R-HSA-202733 Reactome Name: Cell surface interactions at the vascular wall See in Reactome	Hemostasis Signal Transduction	R-HSA-204773 ( R-HSA-210993 ) R-HSA-204773 Reaction Name: Interaction of Tie2 and Grb7 See in Reactome R-HSA-204779 ( R-HSA-210993 ) R-HSA-204779 Reaction Name: Interaction of Tie2 with Ang1 See in Reactome R-HSA-204798 ( R-HSA-210993 ) R-HSA-204798 Reaction Name: Interaction of Tie2 and p85 of PI3K See in Reactome R-HSA-204813 ( R-HSA-210993 ) R-HSA-204813 Reaction Name: Interaction of Tie2 and Grb14 See in Reactome R-HSA-204824 ( R-HSA-210993 ) R-HSA-204824 Reaction Name: Interaction of Tie2 and Ang4 See in Reactome R-HSA-204850 ( R-HSA-210993 ) R-HSA-204850 Reaction Name: Interaction of Tie2 and Dok-2 See in Reactome R-HSA-204861 ( R-HSA-210993 ) R-HSA-204861 Reaction Name: Interaction of Tie2 and Shc1 See in Reactome R-HSA-204863 ( R-HSA-210993 ) R-HSA-204863 Reaction Name: Interaction of Tie2 with Ang2 See in Reactome R-HSA-204871 ( R-HSA-210993 ) R-HSA-204871 Reaction Name: Interaction of Tie2 and Grb2 See in Reactome R-HSA-204873 ( R-HSA-210993 ) R-HSA-204873 Reaction Name: Interaction of Tie2 and Shp2 See in Reactome R-HSA-210872 ( R-HSA-210993 ) R-HSA-210872 Reaction Name: Trans-phosphorylation of Tie2 See in Reactome R-HSA-210881 ( R-HSA-210993 ) R-HSA-210881 Reaction Name: Dimerization of Tie2/Ang1 complex See in Reactome R-HSA-210974 ( R-HSA-210993 ) R-HSA-210974 Reaction Name: Interaction of SOS-1 to Tie2 bound Grb2 See in Reactome R-HSA-210977 ( R-HSA-210993 ) R-HSA-210977 Reaction Name: Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) See in Reactome R-HSA-5672965 ( R-HSA-5673001 ) R-HSA-5672965 Reaction Name: RAS GEFs promote RAS nucleotide exchange See in Reactome
MONDO:0010842	TEK	Q02763	2.7.10.1	R-HSA-210993 R-HSA-210993 Reactome Name: Tie2 Signaling See in Reactome R-HSA-5673001 R-HSA-5673001 Reactome Name: RAF/MAP kinase cascade See in Reactome	R-HSA-109582 R-HSA-109582 Reactome Name: Hemostasis See in Reactome R-HSA-5684996 R-HSA-5684996 Reactome Name: MAPK1/MAPK3 signaling See in Reactome R-HSA-5683057 R-HSA-5683057 Reactome Name: MAPK family signaling cascades See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-202733 R-HSA-202733 Reactome Name: Cell surface interactions at the vascular wall See in Reactome	Hemostasis Signal Transduction	R-HSA-204773 ( R-HSA-210993 ) R-HSA-204773 Reaction Name: Interaction of Tie2 and Grb7 See in Reactome R-HSA-204779 ( R-HSA-210993 ) R-HSA-204779 Reaction Name: Interaction of Tie2 with Ang1 See in Reactome R-HSA-204798 ( R-HSA-210993 ) R-HSA-204798 Reaction Name: Interaction of Tie2 and p85 of PI3K See in Reactome R-HSA-204813 ( R-HSA-210993 ) R-HSA-204813 Reaction Name: Interaction of Tie2 and Grb14 See in Reactome R-HSA-204824 ( R-HSA-210993 ) R-HSA-204824 Reaction Name: Interaction of Tie2 and Ang4 See in Reactome R-HSA-204850 ( R-HSA-210993 ) R-HSA-204850 Reaction Name: Interaction of Tie2 and Dok-2 See in Reactome R-HSA-204861 ( R-HSA-210993 ) R-HSA-204861 Reaction Name: Interaction of Tie2 and Shc1 See in Reactome R-HSA-204863 ( R-HSA-210993 ) R-HSA-204863 Reaction Name: Interaction of Tie2 with Ang2 See in Reactome R-HSA-204871 ( R-HSA-210993 ) R-HSA-204871 Reaction Name: Interaction of Tie2 and Grb2 See in Reactome R-HSA-204873 ( R-HSA-210993 ) R-HSA-204873 Reaction Name: Interaction of Tie2 and Shp2 See in Reactome R-HSA-210872 ( R-HSA-210993 ) R-HSA-210872 Reaction Name: Trans-phosphorylation of Tie2 See in Reactome R-HSA-210881 ( R-HSA-210993 ) R-HSA-210881 Reaction Name: Dimerization of Tie2/Ang1 complex See in Reactome R-HSA-210974 ( R-HSA-210993 ) R-HSA-210974 Reaction Name: Interaction of SOS-1 to Tie2 bound Grb2 See in Reactome R-HSA-210977 ( R-HSA-210993 ) R-HSA-210977 Reaction Name: Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) See in Reactome R-HSA-5672965 ( R-HSA-5673001 ) R-HSA-5672965 Reaction Name: RAS GEFs promote RAS nucleotide exchange See in Reactome
MONDO:0014998	TEK	Q02763	2.7.10.1	R-HSA-210993 R-HSA-210993 Reactome Name: Tie2 Signaling See in Reactome R-HSA-5673001 R-HSA-5673001 Reactome Name: RAF/MAP kinase cascade See in Reactome	R-HSA-109582 R-HSA-109582 Reactome Name: Hemostasis See in Reactome R-HSA-5684996 R-HSA-5684996 Reactome Name: MAPK1/MAPK3 signaling See in Reactome R-HSA-5683057 R-HSA-5683057 Reactome Name: MAPK family signaling cascades See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-202733 R-HSA-202733 Reactome Name: Cell surface interactions at the vascular wall See in Reactome	Hemostasis Signal Transduction	R-HSA-204773 ( R-HSA-210993 ) R-HSA-204773 Reaction Name: Interaction of Tie2 and Grb7 See in Reactome R-HSA-204779 ( R-HSA-210993 ) R-HSA-204779 Reaction Name: Interaction of Tie2 with Ang1 See in Reactome R-HSA-204798 ( R-HSA-210993 ) R-HSA-204798 Reaction Name: Interaction of Tie2 and p85 of PI3K See in Reactome R-HSA-204813 ( R-HSA-210993 ) R-HSA-204813 Reaction Name: Interaction of Tie2 and Grb14 See in Reactome R-HSA-204824 ( R-HSA-210993 ) R-HSA-204824 Reaction Name: Interaction of Tie2 and Ang4 See in Reactome R-HSA-204850 ( R-HSA-210993 ) R-HSA-204850 Reaction Name: Interaction of Tie2 and Dok-2 See in Reactome R-HSA-204861 ( R-HSA-210993 ) R-HSA-204861 Reaction Name: Interaction of Tie2 and Shc1 See in Reactome R-HSA-204863 ( R-HSA-210993 ) R-HSA-204863 Reaction Name: Interaction of Tie2 with Ang2 See in Reactome R-HSA-204871 ( R-HSA-210993 ) R-HSA-204871 Reaction Name: Interaction of Tie2 and Grb2 See in Reactome R-HSA-204873 ( R-HSA-210993 ) R-HSA-204873 Reaction Name: Interaction of Tie2 and Shp2 See in Reactome R-HSA-210872 ( R-HSA-210993 ) R-HSA-210872 Reaction Name: Trans-phosphorylation of Tie2 See in Reactome R-HSA-210881 ( R-HSA-210993 ) R-HSA-210881 Reaction Name: Dimerization of Tie2/Ang1 complex See in Reactome R-HSA-210974 ( R-HSA-210993 ) R-HSA-210974 Reaction Name: Interaction of SOS-1 to Tie2 bound Grb2 See in Reactome R-HSA-210977 ( R-HSA-210993 ) R-HSA-210977 Reaction Name: Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) See in Reactome R-HSA-5672965 ( R-HSA-5673001 ) R-HSA-5672965 Reaction Name: RAS GEFs promote RAS nucleotide exchange See in Reactome