DAR - Bologna Biocomputing Group

Search summary (UniProt accession: Q00535)

Number of enzymes:	1
Number of disease:	1
Number of reactomes:	6
Number of reactions:	10

Search results (UniProt accession: Q00535)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0014596	CDK5	Q00535	2.7.11.1	R-HSA-180024 R-HSA-180024 Reactome Name: DARPP-32 events See in Reactome R-HSA-399956 R-HSA-399956 Reactome Name: CRMPs in Sema3A signaling See in Reactome R-HSA-6804756 R-HSA-6804756 Reactome Name: Regulation of TP53 Activity through Phosphorylation See in Reactome R-HSA-9032845 R-HSA-9032845 Reactome Name: Activated NTRK2 signals through CDK5 See in Reactome R-HSA-9031628 R-HSA-9031628 Reactome Name: NGF-stimulated transcription See in Reactome R-HSA-983231 R-HSA-983231 Reactome Name: Factors involved in megakaryocyte development and platelet production See in Reactome	R-HSA-3700989 R-HSA-3700989 Reactome Name: Transcriptional Regulation by TP53 See in Reactome R-HSA-5633007 R-HSA-5633007 Reactome Name: Regulation of TP53 Activity See in Reactome R-HSA-166520 R-HSA-166520 Reactome Name: Signaling by NTRKs See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-418594 R-HSA-418594 Reactome Name: G alpha (i) signalling events See in Reactome R-HSA-111885 R-HSA-111885 Reactome Name: Opioid Signalling See in Reactome R-HSA-9006115 R-HSA-9006115 Reactome Name: Signaling by NTRK2 (TRKB) See in Reactome R-HSA-9675108 R-HSA-9675108 Reactome Name: Nervous system development See in Reactome R-HSA-388396 R-HSA-388396 Reactome Name: GPCR downstream signalling See in Reactome R-HSA-198725 R-HSA-198725 Reactome Name: Nuclear Events (kinase and transcription factor activation) See in Reactome R-HSA-187037 R-HSA-187037 Reactome Name: Signaling by NTRK1 (TRKA) See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-373755 R-HSA-373755 Reactome Name: Semaphorin interactions See in Reactome R-HSA-9006934 R-HSA-9006934 Reactome Name: Signaling by Receptor Tyrosine Kinases See in Reactome R-HSA-422475 R-HSA-422475 Reactome Name: Axon guidance See in Reactome R-HSA-372790 R-HSA-372790 Reactome Name: Signaling by GPCR See in Reactome R-HSA-109582 R-HSA-109582 Reactome Name: Hemostasis See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome	Signal Transduction Gene expression (Transcription) Hemostasis Developmental Biology	R-HSA-1013833 ( R-HSA-983231 ) R-HSA-1013833 Reaction Name: Cables link CDK5 and ABL1 See in Reactome R-HSA-180047 ( R-HSA-180024 ) R-HSA-180047 Reaction Name: CDK5 phosphorylates DARPP-32 on Thr75 See in Reactome R-HSA-399944 ( R-HSA-399956 ) R-HSA-399944 Reaction Name: Phosphorylation of CRMPs by Cdk5 See in Reactome R-HSA-399946 ( R-HSA-399956 ) R-HSA-399946 Reaction Name: Recruitment and activation of Cdk5 See in Reactome R-HSA-399951 ( R-HSA-399956 ) R-HSA-399951 Reaction Name: Phosphorylation of CRMPs by GSK3beta See in Reactome R-HSA-6805276 ( R-HSA-6804756 ) R-HSA-6805276 Reaction Name: CDK5 phosphorylates TP53 See in Reactome R-HSA-9032841 ( R-HSA-9032845 ) R-HSA-9032841 Reaction Name: Activated NTRK2 binds CDK5 See in Reactome R-HSA-9032854 ( R-HSA-9032845 ) R-HSA-9032854 Reaction Name: NTRK2 phosphorylates CDK5 See in Reactome R-HSA-9032863 ( R-HSA-9032845 ) R-HSA-9032863 Reaction Name: CDK5 phosphorylates NTRK2 See in Reactome R-HSA-9616368 ( R-HSA-9031628 ) R-HSA-9616368 Reaction Name: MyrG-CDK5R1,2 bind CDK5 See in Reactome