DAR - Bologna Biocomputing Group

Search summary (UniProt accession: P51532)

Number of enzymes:	1
Number of disease:	4
Number of reactomes:	6
Number of reactions:	10

Search results (UniProt accession: P51532)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0013224	SMARCA4	P51532	3.6.4.-	R-HSA-201722 R-HSA-201722 Reactome Name: Formation of the beta-catenin:TCF transactivating complex See in Reactome R-HSA-8939243 R-HSA-8939243 Reactome Name: RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known See in Reactome R-HSA-3214858 R-HSA-3214858 Reactome Name: RMTs methylate histone arginines See in Reactome R-HSA-1266695 R-HSA-1266695 Reactome Name: Interleukin-7 signaling See in Reactome R-HSA-3247509 R-HSA-3247509 Reactome Name: Chromatin modifying enzymes See in Reactome R-HSA-9619665 R-HSA-9619665 Reactome Name: EGR2 and SOX10-mediated initiation of Schwann cell myelination See in Reactome	R-HSA-195721 R-HSA-195721 Reactome Name: Signaling by WNT See in Reactome R-HSA-449147 R-HSA-449147 Reactome Name: Signaling by Interleukins See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-8878171 R-HSA-8878171 Reactome Name: Transcriptional regulation by RUNX1 See in Reactome R-HSA-9675108 R-HSA-9675108 Reactome Name: Nervous system development See in Reactome R-HSA-1280215 R-HSA-1280215 Reactome Name: Cytokine Signaling in Immune system See in Reactome R-HSA-4839726 R-HSA-4839726 Reactome Name: Chromatin organization See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-201681 R-HSA-201681 Reactome Name: TCF dependent signaling in response to WNT See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome	Gene expression (Transcription) Immune System Chromatin organization Signal Transduction Developmental Biology	R-HSA-3215448 ( R-HSA-3214858; R-HSA-3247509 ) R-HSA-3215448 Reaction Name: SWI/SNF chromatin remodelling complex enhances MEP50:PRMT5 methyltransferase activity See in Reactome R-HSA-3322422 ( R-HSA-201722 ) R-HSA-3322422 Reaction Name: Beta-catenin recruits SMARCA4 See in Reactome R-HSA-5205799 ( R-HSA-3214858; R-HSA-3247509 ) R-HSA-5205799 Reaction Name: CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8) See in Reactome R-HSA-5205861 ( R-HSA-3214858; R-HSA-3247509 ) R-HSA-5205861 Reaction Name: COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3) See in Reactome R-HSA-8865605 ( R-HSA-1266695; R-HSA-3247509 ) R-HSA-8865605 Reaction Name: BRWD1 binds SMARCA4 See in Reactome R-HSA-8938217 ( R-HSA-8939243 ) R-HSA-8938217 Reaction Name: RUNX1 binds the SWI/SNF complex See in Reactome R-HSA-9613644 ( R-HSA-9619665 ) R-HSA-9613644 Reaction Name: SOX10-dependent POU3F1 gene expression See in Reactome R-HSA-9613648 ( R-HSA-9619665 ) R-HSA-9613648 Reaction Name: SOX10 dimer binds the POU3F1 promoter See in Reactome R-HSA-9614787 ( R-HSA-9619665 ) R-HSA-9614787 Reaction Name: MPZ gene expression See in Reactome R-HSA-9614790 ( R-HSA-9619665 ) R-HSA-9614790 Reaction Name: EGR2, SOX10 and SMARCA4 bind the MPZ gene See in Reactome
MONDO:0018761	SMARCA4	P51532	3.6.4.-	R-HSA-201722 R-HSA-201722 Reactome Name: Formation of the beta-catenin:TCF transactivating complex See in Reactome R-HSA-8939243 R-HSA-8939243 Reactome Name: RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known See in Reactome R-HSA-3214858 R-HSA-3214858 Reactome Name: RMTs methylate histone arginines See in Reactome R-HSA-1266695 R-HSA-1266695 Reactome Name: Interleukin-7 signaling See in Reactome R-HSA-3247509 R-HSA-3247509 Reactome Name: Chromatin modifying enzymes See in Reactome R-HSA-9619665 R-HSA-9619665 Reactome Name: EGR2 and SOX10-mediated initiation of Schwann cell myelination See in Reactome	R-HSA-195721 R-HSA-195721 Reactome Name: Signaling by WNT See in Reactome R-HSA-449147 R-HSA-449147 Reactome Name: Signaling by Interleukins See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-8878171 R-HSA-8878171 Reactome Name: Transcriptional regulation by RUNX1 See in Reactome R-HSA-9675108 R-HSA-9675108 Reactome Name: Nervous system development See in Reactome R-HSA-1280215 R-HSA-1280215 Reactome Name: Cytokine Signaling in Immune system See in Reactome R-HSA-4839726 R-HSA-4839726 Reactome Name: Chromatin organization See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-201681 R-HSA-201681 Reactome Name: TCF dependent signaling in response to WNT See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome	Gene expression (Transcription) Immune System Chromatin organization Signal Transduction Developmental Biology	R-HSA-3215448 ( R-HSA-3214858; R-HSA-3247509 ) R-HSA-3215448 Reaction Name: SWI/SNF chromatin remodelling complex enhances MEP50:PRMT5 methyltransferase activity See in Reactome R-HSA-3322422 ( R-HSA-201722 ) R-HSA-3322422 Reaction Name: Beta-catenin recruits SMARCA4 See in Reactome R-HSA-5205799 ( R-HSA-3214858; R-HSA-3247509 ) R-HSA-5205799 Reaction Name: CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8) See in Reactome R-HSA-5205861 ( R-HSA-3214858; R-HSA-3247509 ) R-HSA-5205861 Reaction Name: COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3) See in Reactome R-HSA-8865605 ( R-HSA-1266695; R-HSA-3247509 ) R-HSA-8865605 Reaction Name: BRWD1 binds SMARCA4 See in Reactome R-HSA-8938217 ( R-HSA-8939243 ) R-HSA-8938217 Reaction Name: RUNX1 binds the SWI/SNF complex See in Reactome R-HSA-9613644 ( R-HSA-9619665 ) R-HSA-9613644 Reaction Name: SOX10-dependent POU3F1 gene expression See in Reactome R-HSA-9613648 ( R-HSA-9619665 ) R-HSA-9613648 Reaction Name: SOX10 dimer binds the POU3F1 promoter See in Reactome R-HSA-9614787 ( R-HSA-9619665 ) R-HSA-9614787 Reaction Name: MPZ gene expression See in Reactome R-HSA-9614790 ( R-HSA-9619665 ) R-HSA-9614790 Reaction Name: EGR2, SOX10 and SMARCA4 bind the MPZ gene See in Reactome
MONDO:0003795	SMARCA4	P51532	3.6.4.-	R-HSA-201722 R-HSA-201722 Reactome Name: Formation of the beta-catenin:TCF transactivating complex See in Reactome R-HSA-8939243 R-HSA-8939243 Reactome Name: RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known See in Reactome R-HSA-3214858 R-HSA-3214858 Reactome Name: RMTs methylate histone arginines See in Reactome R-HSA-1266695 R-HSA-1266695 Reactome Name: Interleukin-7 signaling See in Reactome R-HSA-3247509 R-HSA-3247509 Reactome Name: Chromatin modifying enzymes See in Reactome R-HSA-9619665 R-HSA-9619665 Reactome Name: EGR2 and SOX10-mediated initiation of Schwann cell myelination See in Reactome	R-HSA-195721 R-HSA-195721 Reactome Name: Signaling by WNT See in Reactome R-HSA-449147 R-HSA-449147 Reactome Name: Signaling by Interleukins See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-8878171 R-HSA-8878171 Reactome Name: Transcriptional regulation by RUNX1 See in Reactome R-HSA-9675108 R-HSA-9675108 Reactome Name: Nervous system development See in Reactome R-HSA-1280215 R-HSA-1280215 Reactome Name: Cytokine Signaling in Immune system See in Reactome R-HSA-4839726 R-HSA-4839726 Reactome Name: Chromatin organization See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-201681 R-HSA-201681 Reactome Name: TCF dependent signaling in response to WNT See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome	Gene expression (Transcription) Immune System Chromatin organization Signal Transduction Developmental Biology	R-HSA-3215448 ( R-HSA-3214858; R-HSA-3247509 ) R-HSA-3215448 Reaction Name: SWI/SNF chromatin remodelling complex enhances MEP50:PRMT5 methyltransferase activity See in Reactome R-HSA-3322422 ( R-HSA-201722 ) R-HSA-3322422 Reaction Name: Beta-catenin recruits SMARCA4 See in Reactome R-HSA-5205799 ( R-HSA-3214858; R-HSA-3247509 ) R-HSA-5205799 Reaction Name: CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8) See in Reactome R-HSA-5205861 ( R-HSA-3214858; R-HSA-3247509 ) R-HSA-5205861 Reaction Name: COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3) See in Reactome R-HSA-8865605 ( R-HSA-1266695; R-HSA-3247509 ) R-HSA-8865605 Reaction Name: BRWD1 binds SMARCA4 See in Reactome R-HSA-8938217 ( R-HSA-8939243 ) R-HSA-8938217 Reaction Name: RUNX1 binds the SWI/SNF complex See in Reactome R-HSA-9613644 ( R-HSA-9619665 ) R-HSA-9613644 Reaction Name: SOX10-dependent POU3F1 gene expression See in Reactome R-HSA-9613648 ( R-HSA-9619665 ) R-HSA-9613648 Reaction Name: SOX10 dimer binds the POU3F1 promoter See in Reactome R-HSA-9614787 ( R-HSA-9619665 ) R-HSA-9614787 Reaction Name: MPZ gene expression See in Reactome R-HSA-9614790 ( R-HSA-9619665 ) R-HSA-9614790 Reaction Name: EGR2, SOX10 and SMARCA4 bind the MPZ gene See in Reactome
MONDO:0013821	SMARCA4	P51532	3.6.4.-	R-HSA-201722 R-HSA-201722 Reactome Name: Formation of the beta-catenin:TCF transactivating complex See in Reactome R-HSA-8939243 R-HSA-8939243 Reactome Name: RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known See in Reactome R-HSA-3214858 R-HSA-3214858 Reactome Name: RMTs methylate histone arginines See in Reactome R-HSA-1266695 R-HSA-1266695 Reactome Name: Interleukin-7 signaling See in Reactome R-HSA-3247509 R-HSA-3247509 Reactome Name: Chromatin modifying enzymes See in Reactome R-HSA-9619665 R-HSA-9619665 Reactome Name: EGR2 and SOX10-mediated initiation of Schwann cell myelination See in Reactome	R-HSA-195721 R-HSA-195721 Reactome Name: Signaling by WNT See in Reactome R-HSA-449147 R-HSA-449147 Reactome Name: Signaling by Interleukins See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-8878171 R-HSA-8878171 Reactome Name: Transcriptional regulation by RUNX1 See in Reactome R-HSA-9675108 R-HSA-9675108 Reactome Name: Nervous system development See in Reactome R-HSA-1280215 R-HSA-1280215 Reactome Name: Cytokine Signaling in Immune system See in Reactome R-HSA-4839726 R-HSA-4839726 Reactome Name: Chromatin organization See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-201681 R-HSA-201681 Reactome Name: TCF dependent signaling in response to WNT See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome	Gene expression (Transcription) Immune System Chromatin organization Signal Transduction Developmental Biology	R-HSA-3215448 ( R-HSA-3214858; R-HSA-3247509 ) R-HSA-3215448 Reaction Name: SWI/SNF chromatin remodelling complex enhances MEP50:PRMT5 methyltransferase activity See in Reactome R-HSA-3322422 ( R-HSA-201722 ) R-HSA-3322422 Reaction Name: Beta-catenin recruits SMARCA4 See in Reactome R-HSA-5205799 ( R-HSA-3214858; R-HSA-3247509 ) R-HSA-5205799 Reaction Name: CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8) See in Reactome R-HSA-5205861 ( R-HSA-3214858; R-HSA-3247509 ) R-HSA-5205861 Reaction Name: COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3) See in Reactome R-HSA-8865605 ( R-HSA-1266695; R-HSA-3247509 ) R-HSA-8865605 Reaction Name: BRWD1 binds SMARCA4 See in Reactome R-HSA-8938217 ( R-HSA-8939243 ) R-HSA-8938217 Reaction Name: RUNX1 binds the SWI/SNF complex See in Reactome R-HSA-9613644 ( R-HSA-9619665 ) R-HSA-9613644 Reaction Name: SOX10-dependent POU3F1 gene expression See in Reactome R-HSA-9613648 ( R-HSA-9619665 ) R-HSA-9613648 Reaction Name: SOX10 dimer binds the POU3F1 promoter See in Reactome R-HSA-9614787 ( R-HSA-9619665 ) R-HSA-9614787 Reaction Name: MPZ gene expression See in Reactome R-HSA-9614790 ( R-HSA-9619665 ) R-HSA-9614790 Reaction Name: EGR2, SOX10 and SMARCA4 bind the MPZ gene See in Reactome