DAR - Bologna Biocomputing Group

Search summary (UniProt accession: P51451)

Number of enzymes:	1
Number of disease:	2
Number of reactomes:	2
Number of reactions:	2

Search results (UniProt accession: P51451)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0013242	BLK	P51451	2.7.10.2	R-HSA-983695 R-HSA-983695 Reactome Name: Antigen activates B Cell Receptor (BCR) leading to generation of second messengers See in Reactome R-HSA-8939245 R-HSA-8939245 Reactome Name: RUNX1 regulates transcription of genes involved in BCR signaling See in Reactome	R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-8878171 R-HSA-8878171 Reactome Name: Transcriptional regulation by RUNX1 See in Reactome R-HSA-983705 R-HSA-983705 Reactome Name: Signaling by the B Cell Receptor (BCR) See in Reactome R-HSA-1280218 R-HSA-1280218 Reactome Name: Adaptive Immune System See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome	Gene expression (Transcription) Immune System	R-HSA-8938987 ( R-HSA-8939245 ) R-HSA-8938987 Reaction Name: BLK gene expression is stimulated by the complex of RUNX1 and ELF1, ELF2 or PAX5 See in Reactome R-HSA-983709 ( R-HSA-983695 ) R-HSA-983709 Reaction Name: LYN, FYN, BLK phosphorylate ITAMs of Ig-alpha (CD79A) and Ig-beta (CD79B) See in Reactome
MONDO:0007915	BLK	P51451	2.7.10.2	R-HSA-983695 R-HSA-983695 Reactome Name: Antigen activates B Cell Receptor (BCR) leading to generation of second messengers See in Reactome R-HSA-8939245 R-HSA-8939245 Reactome Name: RUNX1 regulates transcription of genes involved in BCR signaling See in Reactome	R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-8878171 R-HSA-8878171 Reactome Name: Transcriptional regulation by RUNX1 See in Reactome R-HSA-983705 R-HSA-983705 Reactome Name: Signaling by the B Cell Receptor (BCR) See in Reactome R-HSA-1280218 R-HSA-1280218 Reactome Name: Adaptive Immune System See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome	Gene expression (Transcription) Immune System	R-HSA-8938987 ( R-HSA-8939245 ) R-HSA-8938987 Reaction Name: BLK gene expression is stimulated by the complex of RUNX1 and ELF1, ELF2 or PAX5 See in Reactome R-HSA-983709 ( R-HSA-983695 ) R-HSA-983709 Reaction Name: LYN, FYN, BLK phosphorylate ITAMs of Ig-alpha (CD79A) and Ig-beta (CD79B) See in Reactome