DAR - Bologna Biocomputing Group

Search summary (UniProt accession: P48449)

Number of enzymes:	1
Number of disease:	5
Number of reactomes:	2
Number of reactions:	2

Search results (UniProt accession: P48449)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0030009	LSS	P48449	5.4.99.7	R-HSA-191273 R-HSA-191273 Reactome Name: Cholesterol biosynthesis See in Reactome R-HSA-2426168 R-HSA-2426168 Reactome Name: Activation of gene expression by SREBF (SREBP) See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-1655829 R-HSA-1655829 Reactome Name: Regulation of cholesterol biosynthesis by SREBP (SREBF) See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome	Metabolism	R-HSA-1655828 ( R-HSA-2426168 ) R-HSA-1655828 Reaction Name: Expression of Lanosterol Synthase (LSS) See in Reactome R-HSA-191366 ( R-HSA-191273 ) R-HSA-191366 Reaction Name: Squalene 2,3-epoxide cyclizes, forming lanosterol See in Reactome
MONDO:0032649	LSS	P48449	5.4.99.7	R-HSA-191273 R-HSA-191273 Reactome Name: Cholesterol biosynthesis See in Reactome R-HSA-2426168 R-HSA-2426168 Reactome Name: Activation of gene expression by SREBF (SREBP) See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-1655829 R-HSA-1655829 Reactome Name: Regulation of cholesterol biosynthesis by SREBP (SREBF) See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome	Metabolism	R-HSA-1655828 ( R-HSA-2426168 ) R-HSA-1655828 Reaction Name: Expression of Lanosterol Synthase (LSS) See in Reactome R-HSA-191366 ( R-HSA-191273 ) R-HSA-191366 Reaction Name: Squalene 2,3-epoxide cyclizes, forming lanosterol See in Reactome
MONDO:0018914	LSS	P48449	5.4.99.7	R-HSA-191273 R-HSA-191273 Reactome Name: Cholesterol biosynthesis See in Reactome R-HSA-2426168 R-HSA-2426168 Reactome Name: Activation of gene expression by SREBF (SREBP) See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-1655829 R-HSA-1655829 Reactome Name: Regulation of cholesterol biosynthesis by SREBP (SREBF) See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome	Metabolism	R-HSA-1655828 ( R-HSA-2426168 ) R-HSA-1655828 Reaction Name: Expression of Lanosterol Synthase (LSS) See in Reactome R-HSA-191366 ( R-HSA-191273 ) R-HSA-191366 Reaction Name: Squalene 2,3-epoxide cyclizes, forming lanosterol See in Reactome
MONDO:0021548	LSS	P48449	5.4.99.7	R-HSA-191273 R-HSA-191273 Reactome Name: Cholesterol biosynthesis See in Reactome R-HSA-2426168 R-HSA-2426168 Reactome Name: Activation of gene expression by SREBF (SREBP) See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-1655829 R-HSA-1655829 Reactome Name: Regulation of cholesterol biosynthesis by SREBP (SREBF) See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome	Metabolism	R-HSA-1655828 ( R-HSA-2426168 ) R-HSA-1655828 Reaction Name: Expression of Lanosterol Synthase (LSS) See in Reactome R-HSA-191366 ( R-HSA-191273 ) R-HSA-191366 Reaction Name: Squalene 2,3-epoxide cyclizes, forming lanosterol See in Reactome
MONDO:0014673	LSS	P48449	5.4.99.7	R-HSA-191273 R-HSA-191273 Reactome Name: Cholesterol biosynthesis See in Reactome R-HSA-2426168 R-HSA-2426168 Reactome Name: Activation of gene expression by SREBF (SREBP) See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-1655829 R-HSA-1655829 Reactome Name: Regulation of cholesterol biosynthesis by SREBP (SREBF) See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome	Metabolism	R-HSA-1655828 ( R-HSA-2426168 ) R-HSA-1655828 Reaction Name: Expression of Lanosterol Synthase (LSS) See in Reactome R-HSA-191366 ( R-HSA-191273 ) R-HSA-191366 Reaction Name: Squalene 2,3-epoxide cyclizes, forming lanosterol See in Reactome