DAR - Bologna Biocomputing Group

Search summary (UniProt accession: P43403)

Number of enzymes:	1
Number of disease:	3
Number of reactomes:	3
Number of reactions:	8

Search results (UniProt accession: P43403)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0012161	ZAP70	P43403	2.7.10.2	R-HSA-202433 R-HSA-202433 Reactome Name: Generation of second messenger molecules See in Reactome R-HSA-9013407 R-HSA-9013407 Reactome Name: RHOH GTPase cycle See in Reactome R-HSA-202430 R-HSA-202430 Reactome Name: Translocation of ZAP-70 to Immunological synapse See in Reactome	R-HSA-9012999 R-HSA-9012999 Reactome Name: RHO GTPase cycle See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-194315 R-HSA-194315 Reactome Name: Signaling by Rho GTPases See in Reactome R-HSA-202403 R-HSA-202403 Reactome Name: TCR signaling See in Reactome R-HSA-9716542 R-HSA-9716542 Reactome Name: Signaling by Rho GTPases, Miro GTPases and RHOBTB3 See in Reactome R-HSA-1280218 R-HSA-1280218 Reactome Name: Adaptive Immune System See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Immune System Signal Transduction	R-HSA-202168 ( R-HSA-202430 ) R-HSA-202168 Reaction Name: Phosphorylation of ZAP-70 by Lck See in Reactome R-HSA-202174 ( R-HSA-202430 ) R-HSA-202174 Reaction Name: Activation of ZAP-70 See in Reactome R-HSA-202216 ( R-HSA-202433 ) R-HSA-202216 Reaction Name: Phosphorylation of SLP-76 See in Reactome R-HSA-202245 ( R-HSA-202433 ) R-HSA-202245 Reaction Name: Phosphorylation of TBSMs in LAT See in Reactome R-HSA-202248 ( R-HSA-202433 ) R-HSA-202248 Reaction Name: Phosphorylation of PLC-gamma1 See in Reactome R-HSA-202344 ( R-HSA-202430 ) R-HSA-202344 Reaction Name: Recruitment of ZAP-70 to phosphorylated ITAMs See in Reactome R-HSA-8855381 ( R-HSA-202430 ) R-HSA-8855381 Reaction Name: PTPN22 dephosphorylates ZAP70 See in Reactome R-HSA-9018758 ( R-HSA-9013407 ) R-HSA-9018758 Reaction Name: RHOH binds effectors at the plasma membrane See in Reactome
MONDO:0014861	ZAP70	P43403	2.7.10.2	R-HSA-202433 R-HSA-202433 Reactome Name: Generation of second messenger molecules See in Reactome R-HSA-9013407 R-HSA-9013407 Reactome Name: RHOH GTPase cycle See in Reactome R-HSA-202430 R-HSA-202430 Reactome Name: Translocation of ZAP-70 to Immunological synapse See in Reactome	R-HSA-9012999 R-HSA-9012999 Reactome Name: RHO GTPase cycle See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-194315 R-HSA-194315 Reactome Name: Signaling by Rho GTPases See in Reactome R-HSA-202403 R-HSA-202403 Reactome Name: TCR signaling See in Reactome R-HSA-9716542 R-HSA-9716542 Reactome Name: Signaling by Rho GTPases, Miro GTPases and RHOBTB3 See in Reactome R-HSA-1280218 R-HSA-1280218 Reactome Name: Adaptive Immune System See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Immune System Signal Transduction	R-HSA-202168 ( R-HSA-202430 ) R-HSA-202168 Reaction Name: Phosphorylation of ZAP-70 by Lck See in Reactome R-HSA-202174 ( R-HSA-202430 ) R-HSA-202174 Reaction Name: Activation of ZAP-70 See in Reactome R-HSA-202216 ( R-HSA-202433 ) R-HSA-202216 Reaction Name: Phosphorylation of SLP-76 See in Reactome R-HSA-202245 ( R-HSA-202433 ) R-HSA-202245 Reaction Name: Phosphorylation of TBSMs in LAT See in Reactome R-HSA-202248 ( R-HSA-202433 ) R-HSA-202248 Reaction Name: Phosphorylation of PLC-gamma1 See in Reactome R-HSA-202344 ( R-HSA-202430 ) R-HSA-202344 Reaction Name: Recruitment of ZAP-70 to phosphorylated ITAMs See in Reactome R-HSA-8855381 ( R-HSA-202430 ) R-HSA-8855381 Reaction Name: PTPN22 dephosphorylates ZAP70 See in Reactome R-HSA-9018758 ( R-HSA-9013407 ) R-HSA-9018758 Reaction Name: RHOH binds effectors at the plasma membrane See in Reactome
MONDO:0010023	ZAP70	P43403	2.7.10.2	R-HSA-202433 R-HSA-202433 Reactome Name: Generation of second messenger molecules See in Reactome R-HSA-9013407 R-HSA-9013407 Reactome Name: RHOH GTPase cycle See in Reactome R-HSA-202430 R-HSA-202430 Reactome Name: Translocation of ZAP-70 to Immunological synapse See in Reactome	R-HSA-9012999 R-HSA-9012999 Reactome Name: RHO GTPase cycle See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-194315 R-HSA-194315 Reactome Name: Signaling by Rho GTPases See in Reactome R-HSA-202403 R-HSA-202403 Reactome Name: TCR signaling See in Reactome R-HSA-9716542 R-HSA-9716542 Reactome Name: Signaling by Rho GTPases, Miro GTPases and RHOBTB3 See in Reactome R-HSA-1280218 R-HSA-1280218 Reactome Name: Adaptive Immune System See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Immune System Signal Transduction	R-HSA-202168 ( R-HSA-202430 ) R-HSA-202168 Reaction Name: Phosphorylation of ZAP-70 by Lck See in Reactome R-HSA-202174 ( R-HSA-202430 ) R-HSA-202174 Reaction Name: Activation of ZAP-70 See in Reactome R-HSA-202216 ( R-HSA-202433 ) R-HSA-202216 Reaction Name: Phosphorylation of SLP-76 See in Reactome R-HSA-202245 ( R-HSA-202433 ) R-HSA-202245 Reaction Name: Phosphorylation of TBSMs in LAT See in Reactome R-HSA-202248 ( R-HSA-202433 ) R-HSA-202248 Reaction Name: Phosphorylation of PLC-gamma1 See in Reactome R-HSA-202344 ( R-HSA-202430 ) R-HSA-202344 Reaction Name: Recruitment of ZAP-70 to phosphorylated ITAMs See in Reactome R-HSA-8855381 ( R-HSA-202430 ) R-HSA-8855381 Reaction Name: PTPN22 dephosphorylates ZAP70 See in Reactome R-HSA-9018758 ( R-HSA-9013407 ) R-HSA-9018758 Reaction Name: RHOH binds effectors at the plasma membrane See in Reactome