DAR - Bologna Biocomputing Group

Search summary (UniProt accession: P35916)

Number of enzymes:	1
Number of disease:	4
Number of reactomes:	2
Number of reactions:	2

Search results (UniProt accession: P35916)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0007919	FLT4	P35916	2.7.10.1	R-HSA-195399 R-HSA-195399 Reactome Name: VEGF binds to VEGFR leading to receptor dimerization See in Reactome R-HSA-9013695 R-HSA-9013695 Reactome Name: NOTCH4 Intracellular Domain Regulates Transcription See in Reactome	R-HSA-194138 R-HSA-194138 Reactome Name: Signaling by VEGF See in Reactome R-HSA-194313 R-HSA-194313 Reactome Name: VEGF ligand-receptor interactions See in Reactome R-HSA-157118 R-HSA-157118 Reactome Name: Signaling by NOTCH See in Reactome R-HSA-9006934 R-HSA-9006934 Reactome Name: Signaling by Receptor Tyrosine Kinases See in Reactome R-HSA-9013694 R-HSA-9013694 Reactome Name: Signaling by NOTCH4 See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Signal Transduction	R-HSA-194308 ( R-HSA-195399 ) R-HSA-194308 Reaction Name: VEGF-C,D bind to VEGFR3 leading to receptor dimerization See in Reactome R-HSA-9604471 ( R-HSA-9013695 ) R-HSA-9604471 Reaction Name: FLT4 gene expression is stimulated by NOTCH4 See in Reactome
MONDO:0008542	FLT4	P35916	2.7.10.1	R-HSA-195399 R-HSA-195399 Reactome Name: VEGF binds to VEGFR leading to receptor dimerization See in Reactome R-HSA-9013695 R-HSA-9013695 Reactome Name: NOTCH4 Intracellular Domain Regulates Transcription See in Reactome	R-HSA-194138 R-HSA-194138 Reactome Name: Signaling by VEGF See in Reactome R-HSA-194313 R-HSA-194313 Reactome Name: VEGF ligand-receptor interactions See in Reactome R-HSA-157118 R-HSA-157118 Reactome Name: Signaling by NOTCH See in Reactome R-HSA-9006934 R-HSA-9006934 Reactome Name: Signaling by Receptor Tyrosine Kinases See in Reactome R-HSA-9013694 R-HSA-9013694 Reactome Name: Signaling by NOTCH4 See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Signal Transduction	R-HSA-194308 ( R-HSA-195399 ) R-HSA-194308 Reaction Name: VEGF-C,D bind to VEGFR3 leading to receptor dimerization See in Reactome R-HSA-9604471 ( R-HSA-9013695 ) R-HSA-9604471 Reaction Name: FLT4 gene expression is stimulated by NOTCH4 See in Reactome
MONDO:0032913	FLT4	P35916	2.7.10.1	R-HSA-195399 R-HSA-195399 Reactome Name: VEGF binds to VEGFR leading to receptor dimerization See in Reactome R-HSA-9013695 R-HSA-9013695 Reactome Name: NOTCH4 Intracellular Domain Regulates Transcription See in Reactome	R-HSA-194138 R-HSA-194138 Reactome Name: Signaling by VEGF See in Reactome R-HSA-194313 R-HSA-194313 Reactome Name: VEGF ligand-receptor interactions See in Reactome R-HSA-157118 R-HSA-157118 Reactome Name: Signaling by NOTCH See in Reactome R-HSA-9006934 R-HSA-9006934 Reactome Name: Signaling by Receptor Tyrosine Kinases See in Reactome R-HSA-9013694 R-HSA-9013694 Reactome Name: Signaling by NOTCH4 See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Signal Transduction	R-HSA-194308 ( R-HSA-195399 ) R-HSA-194308 Reaction Name: VEGF-C,D bind to VEGFR3 leading to receptor dimerization See in Reactome R-HSA-9604471 ( R-HSA-9013695 ) R-HSA-9604471 Reaction Name: FLT4 gene expression is stimulated by NOTCH4 See in Reactome
MONDO:0011191	FLT4	P35916	2.7.10.1	R-HSA-195399 R-HSA-195399 Reactome Name: VEGF binds to VEGFR leading to receptor dimerization See in Reactome R-HSA-9013695 R-HSA-9013695 Reactome Name: NOTCH4 Intracellular Domain Regulates Transcription See in Reactome	R-HSA-194138 R-HSA-194138 Reactome Name: Signaling by VEGF See in Reactome R-HSA-194313 R-HSA-194313 Reactome Name: VEGF ligand-receptor interactions See in Reactome R-HSA-157118 R-HSA-157118 Reactome Name: Signaling by NOTCH See in Reactome R-HSA-9006934 R-HSA-9006934 Reactome Name: Signaling by Receptor Tyrosine Kinases See in Reactome R-HSA-9013694 R-HSA-9013694 Reactome Name: Signaling by NOTCH4 See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Signal Transduction	R-HSA-194308 ( R-HSA-195399 ) R-HSA-194308 Reaction Name: VEGF-C,D bind to VEGFR3 leading to receptor dimerization See in Reactome R-HSA-9604471 ( R-HSA-9013695 ) R-HSA-9604471 Reaction Name: FLT4 gene expression is stimulated by NOTCH4 See in Reactome