DAR - Bologna Biocomputing Group

Search summary (UniProt accession: P21675)

Number of enzymes:	1
Number of disease:	3
Number of reactomes:	6
Number of reactions:	18

Search results (UniProt accession: P21675)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0018823	TAF1	P21675	2.7.11.1 2.3.1.48	R-HSA-76042 R-HSA-76042 Reactome Name: RNA Polymerase II Transcription Initiation And Promoter Clearance See in Reactome R-HSA-6804756 R-HSA-6804756 Reactome Name: Regulation of TP53 Activity through Phosphorylation See in Reactome R-HSA-75953 R-HSA-75953 Reactome Name: RNA Polymerase II Transcription Initiation See in Reactome R-HSA-73776 R-HSA-73776 Reactome Name: RNA Polymerase II Promoter Escape See in Reactome R-HSA-73779 R-HSA-73779 Reactome Name: RNA Polymerase II Transcription Pre-Initiation And Promoter Opening See in Reactome R-HSA-674695 R-HSA-674695 Reactome Name: RNA Polymerase II Pre-transcription Events See in Reactome	R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-3700989 R-HSA-3700989 Reactome Name: Transcriptional Regulation by TP53 See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome R-HSA-5633007 R-HSA-5633007 Reactome Name: Regulation of TP53 Activity See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome	Gene expression (Transcription)	R-HSA-109636 ( R-HSA-73779 ) R-HSA-109636 Reaction Name: Recognition and Binding of Core Promoter Elements by TFIID See in Reactome R-HSA-109637 ( R-HSA-73779 ) R-HSA-109637 Reaction Name: Binding of TFIIA and TFIIB to the pol II promoter:TFIID complex See in Reactome R-HSA-109638 ( R-HSA-73779 ) R-HSA-109638 Reaction Name: Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex See in Reactome R-HSA-109639 ( R-HSA-73779 ) R-HSA-109639 Reaction Name: Formation of the closed pre-initiation complex See in Reactome R-HSA-6805399 ( R-HSA-6804756 ) R-HSA-6805399 Reaction Name: TAF1 phosphorylates TP53 See in Reactome R-HSA-73946 ( R-HSA-674695 ) R-HSA-73946 Reaction Name: Abortive initiation after formation of the first phosphodiester bond See in Reactome R-HSA-75095 ( R-HSA-73779 ) R-HSA-75095 Reaction Name: Binding of TFIIE to the growing preinitiation complex See in Reactome R-HSA-75850 ( R-HSA-73776; R-HSA-76042 ) R-HSA-75850 Reaction Name: Addition of the third nucleotide on the nascent transcript See in Reactome R-HSA-75856 ( R-HSA-674695 ) R-HSA-75856 Reaction Name: Abortive Initiation Before Second Transition See in Reactome R-HSA-75861 ( R-HSA-75953; R-HSA-76042 ) R-HSA-75861 Reaction Name: NTP Binds Active Site of RNA Polymerase II See in Reactome R-HSA-75862 ( R-HSA-674695 ) R-HSA-75862 Reaction Name: Fall Back to Closed Pre-initiation Complex See in Reactome R-HSA-75864 ( R-HSA-75953; R-HSA-76042 ) R-HSA-75864 Reaction Name: Newly Formed Phosphodiester Bond Stabilized and PPi Released See in Reactome R-HSA-75866 ( R-HSA-75953; R-HSA-76042 ) R-HSA-75866 Reaction Name: Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP See in Reactome R-HSA-75869 ( R-HSA-73776; R-HSA-76042 ) R-HSA-75869 Reaction Name: Addition of the fourth nucleotide on the Nascent Transcript: Second Transition See in Reactome R-HSA-75873 ( R-HSA-73776; R-HSA-76042 ) R-HSA-75873 Reaction Name: Addition of Nucleotides 5 through 9 on the growing Transcript See in Reactome R-HSA-75949 ( R-HSA-76042 ) R-HSA-75949 Reaction Name: RNA Polymerase II Promoter Opening: First Transition See in Reactome R-HSA-9613494 ( R-HSA-73776; R-HSA-76042 ) R-HSA-9613494 Reaction Name: Unwinding of DNA for the Nascent Transcript: Second Transition See in Reactome R-HSA-9613497 ( R-HSA-73776; R-HSA-76042 ) R-HSA-9613497 Reaction Name: Unwinding DNA for the nascent transcript See in Reactome
MONDO:0010500	TAF1	P21675	2.7.11.1 2.3.1.48	R-HSA-76042 R-HSA-76042 Reactome Name: RNA Polymerase II Transcription Initiation And Promoter Clearance See in Reactome R-HSA-6804756 R-HSA-6804756 Reactome Name: Regulation of TP53 Activity through Phosphorylation See in Reactome R-HSA-75953 R-HSA-75953 Reactome Name: RNA Polymerase II Transcription Initiation See in Reactome R-HSA-73776 R-HSA-73776 Reactome Name: RNA Polymerase II Promoter Escape See in Reactome R-HSA-73779 R-HSA-73779 Reactome Name: RNA Polymerase II Transcription Pre-Initiation And Promoter Opening See in Reactome R-HSA-674695 R-HSA-674695 Reactome Name: RNA Polymerase II Pre-transcription Events See in Reactome	R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-3700989 R-HSA-3700989 Reactome Name: Transcriptional Regulation by TP53 See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome R-HSA-5633007 R-HSA-5633007 Reactome Name: Regulation of TP53 Activity See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome	Gene expression (Transcription)	R-HSA-109636 ( R-HSA-73779 ) R-HSA-109636 Reaction Name: Recognition and Binding of Core Promoter Elements by TFIID See in Reactome R-HSA-109637 ( R-HSA-73779 ) R-HSA-109637 Reaction Name: Binding of TFIIA and TFIIB to the pol II promoter:TFIID complex See in Reactome R-HSA-109638 ( R-HSA-73779 ) R-HSA-109638 Reaction Name: Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex See in Reactome R-HSA-109639 ( R-HSA-73779 ) R-HSA-109639 Reaction Name: Formation of the closed pre-initiation complex See in Reactome R-HSA-6805399 ( R-HSA-6804756 ) R-HSA-6805399 Reaction Name: TAF1 phosphorylates TP53 See in Reactome R-HSA-73946 ( R-HSA-674695 ) R-HSA-73946 Reaction Name: Abortive initiation after formation of the first phosphodiester bond See in Reactome R-HSA-75095 ( R-HSA-73779 ) R-HSA-75095 Reaction Name: Binding of TFIIE to the growing preinitiation complex See in Reactome R-HSA-75850 ( R-HSA-73776; R-HSA-76042 ) R-HSA-75850 Reaction Name: Addition of the third nucleotide on the nascent transcript See in Reactome R-HSA-75856 ( R-HSA-674695 ) R-HSA-75856 Reaction Name: Abortive Initiation Before Second Transition See in Reactome R-HSA-75861 ( R-HSA-75953; R-HSA-76042 ) R-HSA-75861 Reaction Name: NTP Binds Active Site of RNA Polymerase II See in Reactome R-HSA-75862 ( R-HSA-674695 ) R-HSA-75862 Reaction Name: Fall Back to Closed Pre-initiation Complex See in Reactome R-HSA-75864 ( R-HSA-75953; R-HSA-76042 ) R-HSA-75864 Reaction Name: Newly Formed Phosphodiester Bond Stabilized and PPi Released See in Reactome R-HSA-75866 ( R-HSA-75953; R-HSA-76042 ) R-HSA-75866 Reaction Name: Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP See in Reactome R-HSA-75869 ( R-HSA-73776; R-HSA-76042 ) R-HSA-75869 Reaction Name: Addition of the fourth nucleotide on the Nascent Transcript: Second Transition See in Reactome R-HSA-75873 ( R-HSA-73776; R-HSA-76042 ) R-HSA-75873 Reaction Name: Addition of Nucleotides 5 through 9 on the growing Transcript See in Reactome R-HSA-75949 ( R-HSA-76042 ) R-HSA-75949 Reaction Name: RNA Polymerase II Promoter Opening: First Transition See in Reactome R-HSA-9613494 ( R-HSA-73776; R-HSA-76042 ) R-HSA-9613494 Reaction Name: Unwinding of DNA for the Nascent Transcript: Second Transition See in Reactome R-HSA-9613497 ( R-HSA-73776; R-HSA-76042 ) R-HSA-9613497 Reaction Name: Unwinding DNA for the nascent transcript See in Reactome
MONDO:0010747	TAF1	P21675	2.7.11.1 2.3.1.48	R-HSA-76042 R-HSA-76042 Reactome Name: RNA Polymerase II Transcription Initiation And Promoter Clearance See in Reactome R-HSA-6804756 R-HSA-6804756 Reactome Name: Regulation of TP53 Activity through Phosphorylation See in Reactome R-HSA-75953 R-HSA-75953 Reactome Name: RNA Polymerase II Transcription Initiation See in Reactome R-HSA-73776 R-HSA-73776 Reactome Name: RNA Polymerase II Promoter Escape See in Reactome R-HSA-73779 R-HSA-73779 Reactome Name: RNA Polymerase II Transcription Pre-Initiation And Promoter Opening See in Reactome R-HSA-674695 R-HSA-674695 Reactome Name: RNA Polymerase II Pre-transcription Events See in Reactome	R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-3700989 R-HSA-3700989 Reactome Name: Transcriptional Regulation by TP53 See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome R-HSA-5633007 R-HSA-5633007 Reactome Name: Regulation of TP53 Activity See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome	Gene expression (Transcription)	R-HSA-109636 ( R-HSA-73779 ) R-HSA-109636 Reaction Name: Recognition and Binding of Core Promoter Elements by TFIID See in Reactome R-HSA-109637 ( R-HSA-73779 ) R-HSA-109637 Reaction Name: Binding of TFIIA and TFIIB to the pol II promoter:TFIID complex See in Reactome R-HSA-109638 ( R-HSA-73779 ) R-HSA-109638 Reaction Name: Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex See in Reactome R-HSA-109639 ( R-HSA-73779 ) R-HSA-109639 Reaction Name: Formation of the closed pre-initiation complex See in Reactome R-HSA-6805399 ( R-HSA-6804756 ) R-HSA-6805399 Reaction Name: TAF1 phosphorylates TP53 See in Reactome R-HSA-73946 ( R-HSA-674695 ) R-HSA-73946 Reaction Name: Abortive initiation after formation of the first phosphodiester bond See in Reactome R-HSA-75095 ( R-HSA-73779 ) R-HSA-75095 Reaction Name: Binding of TFIIE to the growing preinitiation complex See in Reactome R-HSA-75850 ( R-HSA-73776; R-HSA-76042 ) R-HSA-75850 Reaction Name: Addition of the third nucleotide on the nascent transcript See in Reactome R-HSA-75856 ( R-HSA-674695 ) R-HSA-75856 Reaction Name: Abortive Initiation Before Second Transition See in Reactome R-HSA-75861 ( R-HSA-75953; R-HSA-76042 ) R-HSA-75861 Reaction Name: NTP Binds Active Site of RNA Polymerase II See in Reactome R-HSA-75862 ( R-HSA-674695 ) R-HSA-75862 Reaction Name: Fall Back to Closed Pre-initiation Complex See in Reactome R-HSA-75864 ( R-HSA-75953; R-HSA-76042 ) R-HSA-75864 Reaction Name: Newly Formed Phosphodiester Bond Stabilized and PPi Released See in Reactome R-HSA-75866 ( R-HSA-75953; R-HSA-76042 ) R-HSA-75866 Reaction Name: Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP See in Reactome R-HSA-75869 ( R-HSA-73776; R-HSA-76042 ) R-HSA-75869 Reaction Name: Addition of the fourth nucleotide on the Nascent Transcript: Second Transition See in Reactome R-HSA-75873 ( R-HSA-73776; R-HSA-76042 ) R-HSA-75873 Reaction Name: Addition of Nucleotides 5 through 9 on the growing Transcript See in Reactome R-HSA-75949 ( R-HSA-76042 ) R-HSA-75949 Reaction Name: RNA Polymerase II Promoter Opening: First Transition See in Reactome R-HSA-9613494 ( R-HSA-73776; R-HSA-76042 ) R-HSA-9613494 Reaction Name: Unwinding of DNA for the Nascent Transcript: Second Transition See in Reactome R-HSA-9613497 ( R-HSA-73776; R-HSA-76042 ) R-HSA-9613497 Reaction Name: Unwinding DNA for the nascent transcript See in Reactome