DAR - Bologna Biocomputing Group

Search summary (UniProt accession: P20839)

Number of enzymes:	1
Number of disease:	2
Number of reactomes:	2
Number of reactions:	5

Search results (UniProt accession: P20839)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0013454	IMPDH1	P20839	1.1.1.205	R-HSA-6798695 R-HSA-6798695 Reactome Name: Neutrophil degranulation See in Reactome R-HSA-73817 R-HSA-73817 Reactome Name: Purine ribonucleoside monophosphate biosynthesis See in Reactome	R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-15869 R-HSA-15869 Reactome Name: Metabolism of nucleotides See in Reactome R-HSA-8956320 R-HSA-8956320 Reactome Name: Nucleotide biosynthesis See in Reactome	Metabolism Immune System	R-HSA-6798748 ( R-HSA-6798695 ) R-HSA-6798748 Reaction Name: Exocytosis of secretory granule lumen proteins See in Reactome R-HSA-6798751 ( R-HSA-6798695 ) R-HSA-6798751 Reaction Name: Exocytosis of azurophil granule lumen proteins See in Reactome R-HSA-6800434 ( R-HSA-6798695 ) R-HSA-6800434 Reaction Name: Exocytosis of ficolin-rich granule lumen proteins See in Reactome R-HSA-73794 ( R-HSA-73817 ) R-HSA-73794 Reaction Name: IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] See in Reactome R-HSA-9678749 ( R-HSA-73817 ) R-HSA-9678749 Reaction Name: IMPDH tetramers binds IMPDH inhibitors See in Reactome
MONDO:0008379	IMPDH1	P20839	1.1.1.205	R-HSA-6798695 R-HSA-6798695 Reactome Name: Neutrophil degranulation See in Reactome R-HSA-73817 R-HSA-73817 Reactome Name: Purine ribonucleoside monophosphate biosynthesis See in Reactome	R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-15869 R-HSA-15869 Reactome Name: Metabolism of nucleotides See in Reactome R-HSA-8956320 R-HSA-8956320 Reactome Name: Nucleotide biosynthesis See in Reactome	Metabolism Immune System	R-HSA-6798748 ( R-HSA-6798695 ) R-HSA-6798748 Reaction Name: Exocytosis of secretory granule lumen proteins See in Reactome R-HSA-6798751 ( R-HSA-6798695 ) R-HSA-6798751 Reaction Name: Exocytosis of azurophil granule lumen proteins See in Reactome R-HSA-6800434 ( R-HSA-6798695 ) R-HSA-6800434 Reaction Name: Exocytosis of ficolin-rich granule lumen proteins See in Reactome R-HSA-73794 ( R-HSA-73817 ) R-HSA-73794 Reaction Name: IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] See in Reactome R-HSA-9678749 ( R-HSA-73817 ) R-HSA-9678749 Reaction Name: IMPDH tetramers binds IMPDH inhibitors See in Reactome