DAR - Bologna Biocomputing Group

Search summary (UniProt accession: P18054)

Number of enzymes:	1
Number of disease:	2
Number of reactomes:	6
Number of reactions:	9

Search results (UniProt accession: P18054)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0005575	ALOX12	P18054	1.13.11.- 1.13.11.33 3.3.2.- 1.13.11.31	R-HSA-2142712 R-HSA-2142712 Reactome Name: Synthesis of 12-eicosatetraenoic acid derivatives See in Reactome R-HSA-2142700 R-HSA-2142700 Reactome Name: Synthesis of Lipoxins (LX) See in Reactome R-HSA-9025106 R-HSA-9025106 Reactome Name: Biosynthesis of DPAn-6 SPMs See in Reactome R-HSA-9018677 R-HSA-9018677 Reactome Name: Biosynthesis of DHA-derived SPMs See in Reactome R-HSA-9026290 R-HSA-9026290 Reactome Name: Biosynthesis of DPAn-3-derived maresins See in Reactome R-HSA-2142696 R-HSA-2142696 Reactome Name: Synthesis of Hepoxilins (HX) and Trioxilins (TrX) See in Reactome	R-HSA-9025094 R-HSA-9025094 Reactome Name: Biosynthesis of DPAn-3 SPMs See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8978868 R-HSA-8978868 Reactome Name: Fatty acid metabolism See in Reactome R-HSA-2142753 R-HSA-2142753 Reactome Name: Arachidonic acid metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-9018683 R-HSA-9018683 Reactome Name: Biosynthesis of DPA-derived SPMs See in Reactome R-HSA-9018678 R-HSA-9018678 Reactome Name: Biosynthesis of specialized proresolving mediators (SPMs) See in Reactome	Metabolism	R-HSA-2161775 ( R-HSA-2142700 ) R-HSA-2161775 Reaction Name: ALOX12 oxidises LTA4 to LXA4/B4 See in Reactome R-HSA-2161794 ( R-HSA-2142696 ) R-HSA-2161794 Reaction Name: Arachidonic acid is converted to HXA3/B3 by ALOX12 See in Reactome R-HSA-2161948 ( R-HSA-2142712 ) R-HSA-2161948 Reaction Name: Arachidonic acid is converted to 12-oxoETE by ALOX12 See in Reactome R-HSA-2161964 ( R-HSA-2142712 ) R-HSA-2161964 Reaction Name: Arachidonic acid is oxidised to 12S-HpETE by ALOX12/15 See in Reactome R-HSA-9020274 ( R-HSA-9018677 ) R-HSA-9020274 Reaction Name: ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA See in Reactome R-HSA-9024983 ( R-HSA-9018677 ) R-HSA-9024983 Reaction Name: ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA See in Reactome R-HSA-9025957 ( R-HSA-9025106 ) R-HSA-9025957 Reaction Name: ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 See in Reactome R-HSA-9026006 ( R-HSA-9026290 ) R-HSA-9026006 Reaction Name: ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 See in Reactome R-HSA-9026007 ( R-HSA-9026290 ) R-HSA-9026007 Reaction Name: ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 See in Reactome
MONDO:0007576	ALOX12	P18054	1.13.11.- 1.13.11.33 3.3.2.- 1.13.11.31	R-HSA-2142712 R-HSA-2142712 Reactome Name: Synthesis of 12-eicosatetraenoic acid derivatives See in Reactome R-HSA-2142700 R-HSA-2142700 Reactome Name: Synthesis of Lipoxins (LX) See in Reactome R-HSA-9025106 R-HSA-9025106 Reactome Name: Biosynthesis of DPAn-6 SPMs See in Reactome R-HSA-9018677 R-HSA-9018677 Reactome Name: Biosynthesis of DHA-derived SPMs See in Reactome R-HSA-9026290 R-HSA-9026290 Reactome Name: Biosynthesis of DPAn-3-derived maresins See in Reactome R-HSA-2142696 R-HSA-2142696 Reactome Name: Synthesis of Hepoxilins (HX) and Trioxilins (TrX) See in Reactome	R-HSA-9025094 R-HSA-9025094 Reactome Name: Biosynthesis of DPAn-3 SPMs See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8978868 R-HSA-8978868 Reactome Name: Fatty acid metabolism See in Reactome R-HSA-2142753 R-HSA-2142753 Reactome Name: Arachidonic acid metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-9018683 R-HSA-9018683 Reactome Name: Biosynthesis of DPA-derived SPMs See in Reactome R-HSA-9018678 R-HSA-9018678 Reactome Name: Biosynthesis of specialized proresolving mediators (SPMs) See in Reactome	Metabolism	R-HSA-2161775 ( R-HSA-2142700 ) R-HSA-2161775 Reaction Name: ALOX12 oxidises LTA4 to LXA4/B4 See in Reactome R-HSA-2161794 ( R-HSA-2142696 ) R-HSA-2161794 Reaction Name: Arachidonic acid is converted to HXA3/B3 by ALOX12 See in Reactome R-HSA-2161948 ( R-HSA-2142712 ) R-HSA-2161948 Reaction Name: Arachidonic acid is converted to 12-oxoETE by ALOX12 See in Reactome R-HSA-2161964 ( R-HSA-2142712 ) R-HSA-2161964 Reaction Name: Arachidonic acid is oxidised to 12S-HpETE by ALOX12/15 See in Reactome R-HSA-9020274 ( R-HSA-9018677 ) R-HSA-9020274 Reaction Name: ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA See in Reactome R-HSA-9024983 ( R-HSA-9018677 ) R-HSA-9024983 Reaction Name: ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA See in Reactome R-HSA-9025957 ( R-HSA-9025106 ) R-HSA-9025957 Reaction Name: ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 See in Reactome R-HSA-9026006 ( R-HSA-9026290 ) R-HSA-9026006 Reaction Name: ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 See in Reactome R-HSA-9026007 ( R-HSA-9026290 ) R-HSA-9026007 Reaction Name: ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 See in Reactome