DAR - Bologna Biocomputing Group

Search summary (UniProt accession: P15586)

Number of enzymes:	1
Number of disease:	1
Number of reactomes:	3
Number of reactions:	7

Search results (UniProt accession: P15586)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0009658	GNS	P15586	3.1.6.14	R-HSA-2022857 R-HSA-2022857 Reactome Name: Keratan sulfate degradation See in Reactome R-HSA-432720 R-HSA-432720 Reactome Name: Lysosome Vesicle Biogenesis See in Reactome R-HSA-6798695 R-HSA-6798695 Reactome Name: Neutrophil degranulation See in Reactome	R-HSA-71387 R-HSA-71387 Reactome Name: Metabolism of carbohydrates See in Reactome R-HSA-1638074 R-HSA-1638074 Reactome Name: Keratan sulfate/keratin metabolism See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-199991 R-HSA-199991 Reactome Name: Membrane Trafficking See in Reactome R-HSA-199992 R-HSA-199992 Reactome Name: trans-Golgi Network Vesicle Budding See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-1630316 R-HSA-1630316 Reactome Name: Glycosaminoglycan metabolism See in Reactome R-HSA-5653656 R-HSA-5653656 Reactome Name: Vesicle-mediated transport See in Reactome	Immune System Metabolism Vesicle-mediated transport	R-HSA-1638032 ( R-HSA-2022857 ) R-HSA-1638032 Reaction Name: N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate See in Reactome R-HSA-432688 ( R-HSA-432720 ) R-HSA-432688 Reaction Name: trans-Golgi Network Derived Lysosomal Vesicle Uncoating See in Reactome R-HSA-432706 ( R-HSA-432720 ) R-HSA-432706 Reaction Name: trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly See in Reactome R-HSA-432707 ( R-HSA-432720 ) R-HSA-432707 Reaction Name: trans-Golgi Network Lysosomal Vesicle Scission See in Reactome R-HSA-432712 ( R-HSA-432720 ) R-HSA-432712 Reaction Name: Vamp And trans-Golgi Network AP-1 Binding Coupled With Cargo Capture On Lysosome Vesicle Destined Golgi Membrane See in Reactome R-HSA-6798751 ( R-HSA-6798695 ) R-HSA-6798751 Reaction Name: Exocytosis of azurophil granule lumen proteins See in Reactome R-HSA-6800434 ( R-HSA-6798695 ) R-HSA-6800434 Reaction Name: Exocytosis of ficolin-rich granule lumen proteins See in Reactome