DAR - Bologna Biocomputing Group

Search summary (UniProt accession: P12821)

Number of enzymes:	1
Number of disease:	4
Number of reactomes:	1
Number of reactions:	4

Search results (UniProt accession: P12821)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0013792	ACE	P12821	3.2.1.- 3.4.15.1	R-HSA-2022377 R-HSA-2022377 Reactome Name: Metabolism of Angiotensinogen to Angiotensins See in Reactome	R-HSA-2980736 R-HSA-2980736 Reactome Name: Peptide hormone metabolism See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome	Metabolism of proteins	R-HSA-2022398 ( R-HSA-2022377 ) R-HSA-2022398 Reaction Name: ACE hydrolyzes Angiotensin-(1-9) to Angiotensin-(1-7) See in Reactome R-HSA-2022405 ( R-HSA-2022377 ) R-HSA-2022405 Reaction Name: ACE hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) See in Reactome R-HSA-2065355 ( R-HSA-2022377 ) R-HSA-2065355 Reaction Name: Secreted ACE hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) See in Reactome R-HSA-9614933 ( R-HSA-2022377 ) R-HSA-9614933 Reaction Name: ACEIs bind ACE See in Reactome
MONDO:0012963	ACE	P12821	3.2.1.- 3.4.15.1	R-HSA-2022377 R-HSA-2022377 Reactome Name: Metabolism of Angiotensinogen to Angiotensins See in Reactome	R-HSA-2980736 R-HSA-2980736 Reactome Name: Peptide hormone metabolism See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome	Metabolism of proteins	R-HSA-2022398 ( R-HSA-2022377 ) R-HSA-2022398 Reaction Name: ACE hydrolyzes Angiotensin-(1-9) to Angiotensin-(1-7) See in Reactome R-HSA-2022405 ( R-HSA-2022377 ) R-HSA-2022405 Reaction Name: ACE hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) See in Reactome R-HSA-2065355 ( R-HSA-2022377 ) R-HSA-2065355 Reaction Name: Secreted ACE hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) See in Reactome R-HSA-9614933 ( R-HSA-2022377 ) R-HSA-9614933 Reaction Name: ACEIs bind ACE See in Reactome
MONDO:0009970	ACE	P12821	3.2.1.- 3.4.15.1	R-HSA-2022377 R-HSA-2022377 Reactome Name: Metabolism of Angiotensinogen to Angiotensins See in Reactome	R-HSA-2980736 R-HSA-2980736 Reactome Name: Peptide hormone metabolism See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome	Metabolism of proteins	R-HSA-2022398 ( R-HSA-2022377 ) R-HSA-2022398 Reaction Name: ACE hydrolyzes Angiotensin-(1-9) to Angiotensin-(1-7) See in Reactome R-HSA-2022405 ( R-HSA-2022377 ) R-HSA-2022405 Reaction Name: ACE hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) See in Reactome R-HSA-2065355 ( R-HSA-2022377 ) R-HSA-2065355 Reaction Name: Secreted ACE hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) See in Reactome R-HSA-9614933 ( R-HSA-2022377 ) R-HSA-9614933 Reaction Name: ACEIs bind ACE See in Reactome
MONDO:0019638	ACE	P12821	3.2.1.- 3.4.15.1	R-HSA-2022377 R-HSA-2022377 Reactome Name: Metabolism of Angiotensinogen to Angiotensins See in Reactome	R-HSA-2980736 R-HSA-2980736 Reactome Name: Peptide hormone metabolism See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome	Metabolism of proteins	R-HSA-2022398 ( R-HSA-2022377 ) R-HSA-2022398 Reaction Name: ACE hydrolyzes Angiotensin-(1-9) to Angiotensin-(1-7) See in Reactome R-HSA-2022405 ( R-HSA-2022377 ) R-HSA-2022405 Reaction Name: ACE hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) See in Reactome R-HSA-2065355 ( R-HSA-2022377 ) R-HSA-2065355 Reaction Name: Secreted ACE hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) See in Reactome R-HSA-9614933 ( R-HSA-2022377 ) R-HSA-9614933 Reaction Name: ACEIs bind ACE See in Reactome