DAR - Bologna Biocomputing Group

Search summary (UniProt accession: P11177)

Number of enzymes:	1
Number of disease:	1
Number of reactomes:	4
Number of reactions:	4

Search results (UniProt accession: P11177)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0013580	PDHB	P11177	1.2.4.1	R-HSA-204174 R-HSA-204174 Reactome Name: Regulation of pyruvate dehydrogenase (PDH) complex See in Reactome R-HSA-389661 R-HSA-389661 Reactome Name: Glyoxylate metabolism and glycine degradation See in Reactome R-HSA-70268 R-HSA-70268 Reactome Name: Pyruvate metabolism See in Reactome R-HSA-5362517 R-HSA-5362517 Reactome Name: Signaling by Retinoic Acid See in Reactome	R-HSA-71406 R-HSA-71406 Reactome Name: Pyruvate metabolism and Citric Acid (TCA) cycle See in Reactome R-HSA-71291 R-HSA-71291 Reactome Name: Metabolism of amino acids and derivatives See in Reactome R-HSA-9006931 R-HSA-9006931 Reactome Name: Signaling by Nuclear Receptors See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-1428517 R-HSA-1428517 Reactome Name: The citric acid (TCA) cycle and respiratory electron transport See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Metabolism Signal Transduction	R-HSA-203946 ( R-HSA-204174; R-HSA-5362517; R-HSA-70268 ) R-HSA-203946 Reaction Name: PDK isoforms phosphorylate lipo-PDH See in Reactome R-HSA-204169 ( R-HSA-204174; R-HSA-70268 ) R-HSA-204169 Reaction Name: PDP dephosphorylates p-lipo-PDH See in Reactome R-HSA-6792572 ( R-HSA-389661 ) R-HSA-6792572 Reaction Name: LIPT1 transfers lipoyl group from lipoyl-GCSH to DHs See in Reactome R-HSA-71397 ( R-HSA-70268 ) R-HSA-71397 Reaction Name: lipo-PDH decarboxylates PYR to Ac-CoA See in Reactome