DAR - Bologna Biocomputing Group

Search summary (UniProt accession: P11161)

Number of enzymes:	1
Number of disease:	3
Number of reactomes:	4
Number of reactions:	36

Search results (UniProt accession: P11161)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0011527	EGR2	P11161	2.3.2.-	R-HSA-9031628 R-HSA-9031628 Reactome Name: NGF-stimulated transcription See in Reactome R-HSA-381340 R-HSA-381340 Reactome Name: Transcriptional regulation of white adipocyte differentiation See in Reactome R-HSA-5617472 R-HSA-5617472 Reactome Name: Activation of anterior HOX genes in hindbrain development during early embryogenesis See in Reactome R-HSA-9619665 R-HSA-9619665 Reactome Name: EGR2 and SOX10-mediated initiation of Schwann cell myelination See in Reactome	R-HSA-187037 R-HSA-187037 Reactome Name: Signaling by NTRK1 (TRKA) See in Reactome R-HSA-166520 R-HSA-166520 Reactome Name: Signaling by NTRKs See in Reactome R-HSA-5619507 R-HSA-5619507 Reactome Name: Activation of HOX genes during differentiation See in Reactome R-HSA-9675108 R-HSA-9675108 Reactome Name: Nervous system development See in Reactome R-HSA-9006934 R-HSA-9006934 Reactome Name: Signaling by Receptor Tyrosine Kinases See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-198725 R-HSA-198725 Reactome Name: Nuclear Events (kinase and transcription factor activation) See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Developmental Biology Signal Transduction	R-HSA-381337 ( R-HSA-381340 ) R-HSA-381337 Reaction Name: Expression of CEBPB in adipogenesis See in Reactome R-HSA-5617454 ( R-HSA-5617472 ) R-HSA-5617454 Reaction Name: HOXB1 gene is transcribed See in Reactome R-HSA-5617483 ( R-HSA-5617472 ) R-HSA-5617483 Reaction Name: HOXA2 gene is transcribed See in Reactome R-HSA-5617484 ( R-HSA-5617472 ) R-HSA-5617484 Reaction Name: EGR2 (KROX20) activates HOXA2 expression See in Reactome R-HSA-5617486 ( R-HSA-5617472 ) R-HSA-5617486 Reaction Name: HOXB2 gene is transcribed See in Reactome R-HSA-5617492 ( R-HSA-5617472 ) R-HSA-5617492 Reaction Name: EGR2 (KROX20) activates HOXB2 expression See in Reactome R-HSA-5617661 ( R-HSA-5617472 ) R-HSA-5617661 Reaction Name: MAFB:JUN and EGR2 activate HOXB3 expression See in Reactome R-HSA-5617672 ( R-HSA-5617472 ) R-HSA-5617672 Reaction Name: HOXB3 gene is transcribed See in Reactome R-HSA-9031616 ( R-HSA-9031628 ) R-HSA-9031616 Reaction Name: EGR binds ARC gene See in Reactome R-HSA-9031624 ( R-HSA-9031628 ) R-HSA-9031624 Reaction Name: ARC gene expression See in Reactome R-HSA-9612073 ( R-HSA-9031628 ) R-HSA-9612073 Reaction Name: NGF- and MAPK-dependent EGR1, EGR2 and EGR4 expression See in Reactome R-HSA-9612483 ( R-HSA-9031628 ) R-HSA-9612483 Reaction Name: EGR1,2,3 bind the NAB2 promoter See in Reactome R-HSA-9612493 ( R-HSA-9031628 ) R-HSA-9612493 Reaction Name: EGR-dependent NAB2 gene expression See in Reactome R-HSA-9612534 ( R-HSA-9031628 ) R-HSA-9612534 Reaction Name: Expression of ID2 and ID4 is repressed by EGR2:NAB See in Reactome R-HSA-9613210 ( R-HSA-9031628 ) R-HSA-9613210 Reaction Name: EGR1, EGR2 bind the RRAD promoter See in Reactome R-HSA-9613213 ( R-HSA-9031628 ) R-HSA-9613213 Reaction Name: NAB2 and CHD4 bind and repress EGR-mediated RRAD gene expression See in Reactome R-HSA-9613219 ( R-HSA-9031628 ) R-HSA-9613219 Reaction Name: RRAD gene expression See in Reactome R-HSA-9613476 ( R-HSA-9031628 ) R-HSA-9613476 Reaction Name: EGR2:NAB2 and CHD4 bind the ID2 and ID4 promoter regions See in Reactome R-HSA-9613760 ( R-HSA-9619665 ) R-HSA-9613760 Reaction Name: EGR2 gene expression See in Reactome R-HSA-9614773 ( R-HSA-9619665 ) R-HSA-9614773 Reaction Name: MBP gene expression See in Reactome R-HSA-9614778 ( R-HSA-9619665 ) R-HSA-9614778 Reaction Name: MAG gene expression See in Reactome R-HSA-9614787 ( R-HSA-9619665 ) R-HSA-9614787 Reaction Name: MPZ gene expression See in Reactome R-HSA-9614790 ( R-HSA-9619665 ) R-HSA-9614790 Reaction Name: EGR2, SOX10 and SMARCA4 bind the MPZ gene See in Reactome R-HSA-9615626 ( R-HSA-9619665 ) R-HSA-9615626 Reaction Name: PMP22 gene expression See in Reactome R-HSA-9615638 ( R-HSA-9619665 ) R-HSA-9615638 Reaction Name: EGR2 and SOX10 bind the MBP gene See in Reactome R-HSA-9616116 ( R-HSA-9619665 ) R-HSA-9616116 Reaction Name: EGR2 and SOX10 bind the MAG gene See in Reactome R-HSA-9618559 ( R-HSA-9619665 ) R-HSA-9618559 Reaction Name: EGR2, SOX10 and TEAD1 bind enhancers in the PMP22 gene See in Reactome R-HSA-9618725 ( R-HSA-9619665 ) R-HSA-9618725 Reaction Name: SOX10, EGR2 and NAB proteins bind the GJB1 promoter See in Reactome R-HSA-9619657 ( R-HSA-9619665 ) R-HSA-9619657 Reaction Name: EGR2 and SOX10 bind the PRX gene See in Reactome R-HSA-9619667 ( R-HSA-9619665 ) R-HSA-9619667 Reaction Name: PRX gene expression See in Reactome R-HSA-9621399 ( R-HSA-9619665 ) R-HSA-9621399 Reaction Name: SCD5 gene expression See in Reactome R-HSA-9621400 ( R-HSA-9619665 ) R-HSA-9621400 Reaction Name: EGR2 and SREBF2 dimer bind SCD5 gene See in Reactome R-HSA-9621404 ( R-HSA-9619665 ) R-HSA-9621404 Reaction Name: CYP51A1 gene expression See in Reactome R-HSA-9621406 ( R-HSA-9619665 ) R-HSA-9621406 Reaction Name: EGR2 and SREBF2 dimer bind CYP51A1 gene See in Reactome R-HSA-9621410 ( R-HSA-9619665 ) R-HSA-9621410 Reaction Name: HMGCR gene expression See in Reactome R-HSA-9621411 ( R-HSA-9619665 ) R-HSA-9621411 Reaction Name: EGR2 and SREBF2(1-484) dimer bind HMGCR gene See in Reactome
MONDO:0007790	EGR2	P11161	2.3.2.-	R-HSA-9031628 R-HSA-9031628 Reactome Name: NGF-stimulated transcription See in Reactome R-HSA-381340 R-HSA-381340 Reactome Name: Transcriptional regulation of white adipocyte differentiation See in Reactome R-HSA-5617472 R-HSA-5617472 Reactome Name: Activation of anterior HOX genes in hindbrain development during early embryogenesis See in Reactome R-HSA-9619665 R-HSA-9619665 Reactome Name: EGR2 and SOX10-mediated initiation of Schwann cell myelination See in Reactome	R-HSA-187037 R-HSA-187037 Reactome Name: Signaling by NTRK1 (TRKA) See in Reactome R-HSA-166520 R-HSA-166520 Reactome Name: Signaling by NTRKs See in Reactome R-HSA-5619507 R-HSA-5619507 Reactome Name: Activation of HOX genes during differentiation See in Reactome R-HSA-9675108 R-HSA-9675108 Reactome Name: Nervous system development See in Reactome R-HSA-9006934 R-HSA-9006934 Reactome Name: Signaling by Receptor Tyrosine Kinases See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-198725 R-HSA-198725 Reactome Name: Nuclear Events (kinase and transcription factor activation) See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Developmental Biology Signal Transduction	R-HSA-381337 ( R-HSA-381340 ) R-HSA-381337 Reaction Name: Expression of CEBPB in adipogenesis See in Reactome R-HSA-5617454 ( R-HSA-5617472 ) R-HSA-5617454 Reaction Name: HOXB1 gene is transcribed See in Reactome R-HSA-5617483 ( R-HSA-5617472 ) R-HSA-5617483 Reaction Name: HOXA2 gene is transcribed See in Reactome R-HSA-5617484 ( R-HSA-5617472 ) R-HSA-5617484 Reaction Name: EGR2 (KROX20) activates HOXA2 expression See in Reactome R-HSA-5617486 ( R-HSA-5617472 ) R-HSA-5617486 Reaction Name: HOXB2 gene is transcribed See in Reactome R-HSA-5617492 ( R-HSA-5617472 ) R-HSA-5617492 Reaction Name: EGR2 (KROX20) activates HOXB2 expression See in Reactome R-HSA-5617661 ( R-HSA-5617472 ) R-HSA-5617661 Reaction Name: MAFB:JUN and EGR2 activate HOXB3 expression See in Reactome R-HSA-5617672 ( R-HSA-5617472 ) R-HSA-5617672 Reaction Name: HOXB3 gene is transcribed See in Reactome R-HSA-9031616 ( R-HSA-9031628 ) R-HSA-9031616 Reaction Name: EGR binds ARC gene See in Reactome R-HSA-9031624 ( R-HSA-9031628 ) R-HSA-9031624 Reaction Name: ARC gene expression See in Reactome R-HSA-9612073 ( R-HSA-9031628 ) R-HSA-9612073 Reaction Name: NGF- and MAPK-dependent EGR1, EGR2 and EGR4 expression See in Reactome R-HSA-9612483 ( R-HSA-9031628 ) R-HSA-9612483 Reaction Name: EGR1,2,3 bind the NAB2 promoter See in Reactome R-HSA-9612493 ( R-HSA-9031628 ) R-HSA-9612493 Reaction Name: EGR-dependent NAB2 gene expression See in Reactome R-HSA-9612534 ( R-HSA-9031628 ) R-HSA-9612534 Reaction Name: Expression of ID2 and ID4 is repressed by EGR2:NAB See in Reactome R-HSA-9613210 ( R-HSA-9031628 ) R-HSA-9613210 Reaction Name: EGR1, EGR2 bind the RRAD promoter See in Reactome R-HSA-9613213 ( R-HSA-9031628 ) R-HSA-9613213 Reaction Name: NAB2 and CHD4 bind and repress EGR-mediated RRAD gene expression See in Reactome R-HSA-9613219 ( R-HSA-9031628 ) R-HSA-9613219 Reaction Name: RRAD gene expression See in Reactome R-HSA-9613476 ( R-HSA-9031628 ) R-HSA-9613476 Reaction Name: EGR2:NAB2 and CHD4 bind the ID2 and ID4 promoter regions See in Reactome R-HSA-9613760 ( R-HSA-9619665 ) R-HSA-9613760 Reaction Name: EGR2 gene expression See in Reactome R-HSA-9614773 ( R-HSA-9619665 ) R-HSA-9614773 Reaction Name: MBP gene expression See in Reactome R-HSA-9614778 ( R-HSA-9619665 ) R-HSA-9614778 Reaction Name: MAG gene expression See in Reactome R-HSA-9614787 ( R-HSA-9619665 ) R-HSA-9614787 Reaction Name: MPZ gene expression See in Reactome R-HSA-9614790 ( R-HSA-9619665 ) R-HSA-9614790 Reaction Name: EGR2, SOX10 and SMARCA4 bind the MPZ gene See in Reactome R-HSA-9615626 ( R-HSA-9619665 ) R-HSA-9615626 Reaction Name: PMP22 gene expression See in Reactome R-HSA-9615638 ( R-HSA-9619665 ) R-HSA-9615638 Reaction Name: EGR2 and SOX10 bind the MBP gene See in Reactome R-HSA-9616116 ( R-HSA-9619665 ) R-HSA-9616116 Reaction Name: EGR2 and SOX10 bind the MAG gene See in Reactome R-HSA-9618559 ( R-HSA-9619665 ) R-HSA-9618559 Reaction Name: EGR2, SOX10 and TEAD1 bind enhancers in the PMP22 gene See in Reactome R-HSA-9618725 ( R-HSA-9619665 ) R-HSA-9618725 Reaction Name: SOX10, EGR2 and NAB proteins bind the GJB1 promoter See in Reactome R-HSA-9619657 ( R-HSA-9619665 ) R-HSA-9619657 Reaction Name: EGR2 and SOX10 bind the PRX gene See in Reactome R-HSA-9619667 ( R-HSA-9619665 ) R-HSA-9619667 Reaction Name: PRX gene expression See in Reactome R-HSA-9621399 ( R-HSA-9619665 ) R-HSA-9621399 Reaction Name: SCD5 gene expression See in Reactome R-HSA-9621400 ( R-HSA-9619665 ) R-HSA-9621400 Reaction Name: EGR2 and SREBF2 dimer bind SCD5 gene See in Reactome R-HSA-9621404 ( R-HSA-9619665 ) R-HSA-9621404 Reaction Name: CYP51A1 gene expression See in Reactome R-HSA-9621406 ( R-HSA-9619665 ) R-HSA-9621406 Reaction Name: EGR2 and SREBF2 dimer bind CYP51A1 gene See in Reactome R-HSA-9621410 ( R-HSA-9619665 ) R-HSA-9621410 Reaction Name: HMGCR gene expression See in Reactome R-HSA-9621411 ( R-HSA-9619665 ) R-HSA-9621411 Reaction Name: EGR2 and SREBF2(1-484) dimer bind HMGCR gene See in Reactome
MONDO:0011890	EGR2	P11161	2.3.2.-	R-HSA-9031628 R-HSA-9031628 Reactome Name: NGF-stimulated transcription See in Reactome R-HSA-381340 R-HSA-381340 Reactome Name: Transcriptional regulation of white adipocyte differentiation See in Reactome R-HSA-5617472 R-HSA-5617472 Reactome Name: Activation of anterior HOX genes in hindbrain development during early embryogenesis See in Reactome R-HSA-9619665 R-HSA-9619665 Reactome Name: EGR2 and SOX10-mediated initiation of Schwann cell myelination See in Reactome	R-HSA-187037 R-HSA-187037 Reactome Name: Signaling by NTRK1 (TRKA) See in Reactome R-HSA-166520 R-HSA-166520 Reactome Name: Signaling by NTRKs See in Reactome R-HSA-5619507 R-HSA-5619507 Reactome Name: Activation of HOX genes during differentiation See in Reactome R-HSA-9675108 R-HSA-9675108 Reactome Name: Nervous system development See in Reactome R-HSA-9006934 R-HSA-9006934 Reactome Name: Signaling by Receptor Tyrosine Kinases See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-198725 R-HSA-198725 Reactome Name: Nuclear Events (kinase and transcription factor activation) See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Developmental Biology Signal Transduction	R-HSA-381337 ( R-HSA-381340 ) R-HSA-381337 Reaction Name: Expression of CEBPB in adipogenesis See in Reactome R-HSA-5617454 ( R-HSA-5617472 ) R-HSA-5617454 Reaction Name: HOXB1 gene is transcribed See in Reactome R-HSA-5617483 ( R-HSA-5617472 ) R-HSA-5617483 Reaction Name: HOXA2 gene is transcribed See in Reactome R-HSA-5617484 ( R-HSA-5617472 ) R-HSA-5617484 Reaction Name: EGR2 (KROX20) activates HOXA2 expression See in Reactome R-HSA-5617486 ( R-HSA-5617472 ) R-HSA-5617486 Reaction Name: HOXB2 gene is transcribed See in Reactome R-HSA-5617492 ( R-HSA-5617472 ) R-HSA-5617492 Reaction Name: EGR2 (KROX20) activates HOXB2 expression See in Reactome R-HSA-5617661 ( R-HSA-5617472 ) R-HSA-5617661 Reaction Name: MAFB:JUN and EGR2 activate HOXB3 expression See in Reactome R-HSA-5617672 ( R-HSA-5617472 ) R-HSA-5617672 Reaction Name: HOXB3 gene is transcribed See in Reactome R-HSA-9031616 ( R-HSA-9031628 ) R-HSA-9031616 Reaction Name: EGR binds ARC gene See in Reactome R-HSA-9031624 ( R-HSA-9031628 ) R-HSA-9031624 Reaction Name: ARC gene expression See in Reactome R-HSA-9612073 ( R-HSA-9031628 ) R-HSA-9612073 Reaction Name: NGF- and MAPK-dependent EGR1, EGR2 and EGR4 expression See in Reactome R-HSA-9612483 ( R-HSA-9031628 ) R-HSA-9612483 Reaction Name: EGR1,2,3 bind the NAB2 promoter See in Reactome R-HSA-9612493 ( R-HSA-9031628 ) R-HSA-9612493 Reaction Name: EGR-dependent NAB2 gene expression See in Reactome R-HSA-9612534 ( R-HSA-9031628 ) R-HSA-9612534 Reaction Name: Expression of ID2 and ID4 is repressed by EGR2:NAB See in Reactome R-HSA-9613210 ( R-HSA-9031628 ) R-HSA-9613210 Reaction Name: EGR1, EGR2 bind the RRAD promoter See in Reactome R-HSA-9613213 ( R-HSA-9031628 ) R-HSA-9613213 Reaction Name: NAB2 and CHD4 bind and repress EGR-mediated RRAD gene expression See in Reactome R-HSA-9613219 ( R-HSA-9031628 ) R-HSA-9613219 Reaction Name: RRAD gene expression See in Reactome R-HSA-9613476 ( R-HSA-9031628 ) R-HSA-9613476 Reaction Name: EGR2:NAB2 and CHD4 bind the ID2 and ID4 promoter regions See in Reactome R-HSA-9613760 ( R-HSA-9619665 ) R-HSA-9613760 Reaction Name: EGR2 gene expression See in Reactome R-HSA-9614773 ( R-HSA-9619665 ) R-HSA-9614773 Reaction Name: MBP gene expression See in Reactome R-HSA-9614778 ( R-HSA-9619665 ) R-HSA-9614778 Reaction Name: MAG gene expression See in Reactome R-HSA-9614787 ( R-HSA-9619665 ) R-HSA-9614787 Reaction Name: MPZ gene expression See in Reactome R-HSA-9614790 ( R-HSA-9619665 ) R-HSA-9614790 Reaction Name: EGR2, SOX10 and SMARCA4 bind the MPZ gene See in Reactome R-HSA-9615626 ( R-HSA-9619665 ) R-HSA-9615626 Reaction Name: PMP22 gene expression See in Reactome R-HSA-9615638 ( R-HSA-9619665 ) R-HSA-9615638 Reaction Name: EGR2 and SOX10 bind the MBP gene See in Reactome R-HSA-9616116 ( R-HSA-9619665 ) R-HSA-9616116 Reaction Name: EGR2 and SOX10 bind the MAG gene See in Reactome R-HSA-9618559 ( R-HSA-9619665 ) R-HSA-9618559 Reaction Name: EGR2, SOX10 and TEAD1 bind enhancers in the PMP22 gene See in Reactome R-HSA-9618725 ( R-HSA-9619665 ) R-HSA-9618725 Reaction Name: SOX10, EGR2 and NAB proteins bind the GJB1 promoter See in Reactome R-HSA-9619657 ( R-HSA-9619665 ) R-HSA-9619657 Reaction Name: EGR2 and SOX10 bind the PRX gene See in Reactome R-HSA-9619667 ( R-HSA-9619665 ) R-HSA-9619667 Reaction Name: PRX gene expression See in Reactome R-HSA-9621399 ( R-HSA-9619665 ) R-HSA-9621399 Reaction Name: SCD5 gene expression See in Reactome R-HSA-9621400 ( R-HSA-9619665 ) R-HSA-9621400 Reaction Name: EGR2 and SREBF2 dimer bind SCD5 gene See in Reactome R-HSA-9621404 ( R-HSA-9619665 ) R-HSA-9621404 Reaction Name: CYP51A1 gene expression See in Reactome R-HSA-9621406 ( R-HSA-9619665 ) R-HSA-9621406 Reaction Name: EGR2 and SREBF2 dimer bind CYP51A1 gene See in Reactome R-HSA-9621410 ( R-HSA-9619665 ) R-HSA-9621410 Reaction Name: HMGCR gene expression See in Reactome R-HSA-9621411 ( R-HSA-9619665 ) R-HSA-9621411 Reaction Name: EGR2 and SREBF2(1-484) dimer bind HMGCR gene See in Reactome