DAR - Bologna Biocomputing Group

Search summary (UniProt accession: P08575)

Number of enzymes:	1
Number of disease:	3
Number of reactomes:	3
Number of reactions:	4

Search results (UniProt accession: P08575)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0012163	PTPRC	P08575	3.1.3.48	R-HSA-6798695 R-HSA-6798695 Reactome Name: Neutrophil degranulation See in Reactome R-HSA-416700 R-HSA-416700 Reactome Name: Other semaphorin interactions See in Reactome R-HSA-202427 R-HSA-202427 Reactome Name: Phosphorylation of CD3 and TCR zeta chains See in Reactome	R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-9675108 R-HSA-9675108 Reactome Name: Nervous system development See in Reactome R-HSA-202403 R-HSA-202403 Reactome Name: TCR signaling See in Reactome R-HSA-373755 R-HSA-373755 Reactome Name: Semaphorin interactions See in Reactome R-HSA-422475 R-HSA-422475 Reactome Name: Axon guidance See in Reactome R-HSA-1280218 R-HSA-1280218 Reactome Name: Adaptive Immune System See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome	Immune System Developmental Biology	R-HSA-202214 ( R-HSA-202427 ) R-HSA-202214 Reaction Name: Dephosphorylation of Lck-pY505 by CD45 See in Reactome R-HSA-202233 ( R-HSA-202427 ) R-HSA-202233 Reaction Name: Inactivation of Lck by Csk See in Reactome R-HSA-373746 ( R-HSA-416700 ) R-HSA-373746 Reaction Name: SEMA4D interacts with CD45 See in Reactome R-HSA-6798743 ( R-HSA-6798695 ) R-HSA-6798743 Reaction Name: Exocytosis of secretory granule membrane proteins See in Reactome
MONDO:0021571	PTPRC	P08575	3.1.3.48	R-HSA-6798695 R-HSA-6798695 Reactome Name: Neutrophil degranulation See in Reactome R-HSA-416700 R-HSA-416700 Reactome Name: Other semaphorin interactions See in Reactome R-HSA-202427 R-HSA-202427 Reactome Name: Phosphorylation of CD3 and TCR zeta chains See in Reactome	R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-9675108 R-HSA-9675108 Reactome Name: Nervous system development See in Reactome R-HSA-202403 R-HSA-202403 Reactome Name: TCR signaling See in Reactome R-HSA-373755 R-HSA-373755 Reactome Name: Semaphorin interactions See in Reactome R-HSA-422475 R-HSA-422475 Reactome Name: Axon guidance See in Reactome R-HSA-1280218 R-HSA-1280218 Reactome Name: Adaptive Immune System See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome	Immune System Developmental Biology	R-HSA-202214 ( R-HSA-202427 ) R-HSA-202214 Reaction Name: Dephosphorylation of Lck-pY505 by CD45 See in Reactome R-HSA-202233 ( R-HSA-202427 ) R-HSA-202233 Reaction Name: Inactivation of Lck by Csk See in Reactome R-HSA-373746 ( R-HSA-416700 ) R-HSA-373746 Reaction Name: SEMA4D interacts with CD45 See in Reactome R-HSA-6798743 ( R-HSA-6798695 ) R-HSA-6798743 Reaction Name: Exocytosis of secretory granule membrane proteins See in Reactome
MONDO:0015702	PTPRC	P08575	3.1.3.48	R-HSA-6798695 R-HSA-6798695 Reactome Name: Neutrophil degranulation See in Reactome R-HSA-416700 R-HSA-416700 Reactome Name: Other semaphorin interactions See in Reactome R-HSA-202427 R-HSA-202427 Reactome Name: Phosphorylation of CD3 and TCR zeta chains See in Reactome	R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-9675108 R-HSA-9675108 Reactome Name: Nervous system development See in Reactome R-HSA-202403 R-HSA-202403 Reactome Name: TCR signaling See in Reactome R-HSA-373755 R-HSA-373755 Reactome Name: Semaphorin interactions See in Reactome R-HSA-422475 R-HSA-422475 Reactome Name: Axon guidance See in Reactome R-HSA-1280218 R-HSA-1280218 Reactome Name: Adaptive Immune System See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome	Immune System Developmental Biology	R-HSA-202214 ( R-HSA-202427 ) R-HSA-202214 Reaction Name: Dephosphorylation of Lck-pY505 by CD45 See in Reactome R-HSA-202233 ( R-HSA-202427 ) R-HSA-202233 Reaction Name: Inactivation of Lck by Csk See in Reactome R-HSA-373746 ( R-HSA-416700 ) R-HSA-373746 Reaction Name: SEMA4D interacts with CD45 See in Reactome R-HSA-6798743 ( R-HSA-6798695 ) R-HSA-6798743 Reaction Name: Exocytosis of secretory granule membrane proteins See in Reactome