DAR - Bologna Biocomputing Group

Search summary (UniProt accession: P03915)

Number of enzymes:	1
Number of disease:	4
Number of reactomes:	2
Number of reactions:	4

Search results (UniProt accession: P03915)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0010790	MT-ND5	P03915	7.1.1.2	R-HSA-6799198 R-HSA-6799198 Reactome Name: Complex I biogenesis See in Reactome R-HSA-611105 R-HSA-611105 Reactome Name: Respiratory electron transport See in Reactome	R-HSA-1428517 R-HSA-1428517 Reactome Name: The citric acid (TCA) cycle and respiratory electron transport See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-163200 R-HSA-163200 Reactome Name: Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. See in Reactome	Metabolism	R-HSA-163217 ( R-HSA-611105 ) R-HSA-163217 Reaction Name: Complex I oxidises NADH to NAD+, reduces CoQ to QH2 See in Reactome R-HSA-6799179 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799179 Reaction Name: Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex See in Reactome R-HSA-6799196 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799196 Reaction Name: The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I See in Reactome R-HSA-6799197 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799197 Reaction Name: ND4, ND5 bind the 550kDa complex to form the 815kDa complex See in Reactome
MONDO:0010788	MT-ND5	P03915	7.1.1.2	R-HSA-6799198 R-HSA-6799198 Reactome Name: Complex I biogenesis See in Reactome R-HSA-611105 R-HSA-611105 Reactome Name: Respiratory electron transport See in Reactome	R-HSA-1428517 R-HSA-1428517 Reactome Name: The citric acid (TCA) cycle and respiratory electron transport See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-163200 R-HSA-163200 Reactome Name: Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. See in Reactome	Metabolism	R-HSA-163217 ( R-HSA-611105 ) R-HSA-163217 Reaction Name: Complex I oxidises NADH to NAD+, reduces CoQ to QH2 See in Reactome R-HSA-6799179 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799179 Reaction Name: Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex See in Reactome R-HSA-6799196 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799196 Reaction Name: The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I See in Reactome R-HSA-6799197 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799197 Reaction Name: ND4, ND5 bind the 550kDa complex to form the 815kDa complex See in Reactome
MONDO:0010789	MT-ND5	P03915	7.1.1.2	R-HSA-6799198 R-HSA-6799198 Reactome Name: Complex I biogenesis See in Reactome R-HSA-611105 R-HSA-611105 Reactome Name: Respiratory electron transport See in Reactome	R-HSA-1428517 R-HSA-1428517 Reactome Name: The citric acid (TCA) cycle and respiratory electron transport See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-163200 R-HSA-163200 Reactome Name: Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. See in Reactome	Metabolism	R-HSA-163217 ( R-HSA-611105 ) R-HSA-163217 Reaction Name: Complex I oxidises NADH to NAD+, reduces CoQ to QH2 See in Reactome R-HSA-6799179 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799179 Reaction Name: Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex See in Reactome R-HSA-6799196 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799196 Reaction Name: The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I See in Reactome R-HSA-6799197 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799197 Reaction Name: ND4, ND5 bind the 550kDa complex to form the 815kDa complex See in Reactome
MONDO:0016814	MT-ND5	P03915	7.1.1.2	R-HSA-6799198 R-HSA-6799198 Reactome Name: Complex I biogenesis See in Reactome R-HSA-611105 R-HSA-611105 Reactome Name: Respiratory electron transport See in Reactome	R-HSA-1428517 R-HSA-1428517 Reactome Name: The citric acid (TCA) cycle and respiratory electron transport See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-163200 R-HSA-163200 Reactome Name: Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. See in Reactome	Metabolism	R-HSA-163217 ( R-HSA-611105 ) R-HSA-163217 Reaction Name: Complex I oxidises NADH to NAD+, reduces CoQ to QH2 See in Reactome R-HSA-6799179 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799179 Reaction Name: Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex See in Reactome R-HSA-6799196 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799196 Reaction Name: The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I See in Reactome R-HSA-6799197 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799197 Reaction Name: ND4, ND5 bind the 550kDa complex to form the 815kDa complex See in Reactome