DAR - Bologna Biocomputing Group

Search summary (UniProt accession: P00750)

Number of enzymes:	1
Number of disease:	2
Number of reactomes:	2
Number of reactions:	9

Search results (UniProt accession: P00750)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0012872	PLAT	P00750	3.4.21.68	R-HSA-186797 R-HSA-186797 Reactome Name: Signaling by PDGF See in Reactome R-HSA-75205 R-HSA-75205 Reactome Name: Dissolution of Fibrin Clot See in Reactome	R-HSA-9006934 R-HSA-9006934 Reactome Name: Signaling by Receptor Tyrosine Kinases See in Reactome R-HSA-109582 R-HSA-109582 Reactome Name: Hemostasis See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Hemostasis Signal Transduction	R-HSA-158744 ( R-HSA-75205 ) R-HSA-158744 Reaction Name: crosslinked fibrin multimer:tissue plasminogen activator (two-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain) + plasmin See in Reactome R-HSA-158747 ( R-HSA-75205 ) R-HSA-158747 Reaction Name: crosslinked fibrin multimer:tissue plasminogen activator (one-chain) -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain) See in Reactome R-HSA-158750 ( R-HSA-75205 ) R-HSA-158750 Reaction Name: crosslinked fibrin multimer:tissue plasminogen activator (one-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain) + plasmin See in Reactome R-HSA-158756 ( R-HSA-75205 ) R-HSA-158756 Reaction Name: crosslinked fibrin multimer:tissue plasminogen activator (two-chain) + plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain):plasminogen See in Reactome R-HSA-158781 ( R-HSA-75205 ) R-HSA-158781 Reaction Name: crosslinked fibrin multimer + tissue plasminogen activator (one-chain) -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain) See in Reactome R-HSA-158784 ( R-HSA-75205 ) R-HSA-158784 Reaction Name: crosslinked fibrin multimer:tissue plasminogen activator (one-chain) + plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain):plasminogen See in Reactome R-HSA-158795 ( R-HSA-75205 ) R-HSA-158795 Reaction Name: fibrin multimer, crosslinked:tissue plasminogen activator (one-chain) + plasminogen activator inhibitor 1 -> fibrin multimer, crosslinked:tissue plasminogen activator (one-chain):plasminogen activator inhibitor 1 See in Reactome R-HSA-158800 ( R-HSA-75205 ) R-HSA-158800 Reaction Name: fibrin multimer, crosslinked:tissue plasminogen activator (two-chain) + plasminogen activator inhibitor 1 -> fibrin multimer, crosslinked:tissue plasminogen activator (two-chain):plasminogen activator inhibitor 1 See in Reactome R-HSA-382061 ( R-HSA-186797 ) R-HSA-382061 Reaction Name: Extracellular processing of novel PDGFs See in Reactome
MONDO:0018810	PLAT	P00750	3.4.21.68	R-HSA-186797 R-HSA-186797 Reactome Name: Signaling by PDGF See in Reactome R-HSA-75205 R-HSA-75205 Reactome Name: Dissolution of Fibrin Clot See in Reactome	R-HSA-9006934 R-HSA-9006934 Reactome Name: Signaling by Receptor Tyrosine Kinases See in Reactome R-HSA-109582 R-HSA-109582 Reactome Name: Hemostasis See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Hemostasis Signal Transduction	R-HSA-158744 ( R-HSA-75205 ) R-HSA-158744 Reaction Name: crosslinked fibrin multimer:tissue plasminogen activator (two-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain) + plasmin See in Reactome R-HSA-158747 ( R-HSA-75205 ) R-HSA-158747 Reaction Name: crosslinked fibrin multimer:tissue plasminogen activator (one-chain) -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain) See in Reactome R-HSA-158750 ( R-HSA-75205 ) R-HSA-158750 Reaction Name: crosslinked fibrin multimer:tissue plasminogen activator (one-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain) + plasmin See in Reactome R-HSA-158756 ( R-HSA-75205 ) R-HSA-158756 Reaction Name: crosslinked fibrin multimer:tissue plasminogen activator (two-chain) + plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain):plasminogen See in Reactome R-HSA-158781 ( R-HSA-75205 ) R-HSA-158781 Reaction Name: crosslinked fibrin multimer + tissue plasminogen activator (one-chain) -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain) See in Reactome R-HSA-158784 ( R-HSA-75205 ) R-HSA-158784 Reaction Name: crosslinked fibrin multimer:tissue plasminogen activator (one-chain) + plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain):plasminogen See in Reactome R-HSA-158795 ( R-HSA-75205 ) R-HSA-158795 Reaction Name: fibrin multimer, crosslinked:tissue plasminogen activator (one-chain) + plasminogen activator inhibitor 1 -> fibrin multimer, crosslinked:tissue plasminogen activator (one-chain):plasminogen activator inhibitor 1 See in Reactome R-HSA-158800 ( R-HSA-75205 ) R-HSA-158800 Reaction Name: fibrin multimer, crosslinked:tissue plasminogen activator (two-chain) + plasminogen activator inhibitor 1 -> fibrin multimer, crosslinked:tissue plasminogen activator (two-chain):plasminogen activator inhibitor 1 See in Reactome R-HSA-382061 ( R-HSA-186797 ) R-HSA-382061 Reaction Name: Extracellular processing of novel PDGFs See in Reactome