DAR - Bologna Biocomputing Group

Search summary (UniProt accession: P00749)

Number of enzymes:	1
Number of disease:	1
Number of reactomes:	2
Number of reactions:	8

Search results (UniProt accession: P00749)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0011136	PLAU	P00749	3.4.21.73	R-HSA-6798695 R-HSA-6798695 Reactome Name: Neutrophil degranulation See in Reactome R-HSA-75205 R-HSA-75205 Reactome Name: Dissolution of Fibrin Clot See in Reactome	R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-109582 R-HSA-109582 Reactome Name: Hemostasis See in Reactome	Immune System Hemostasis	R-HSA-158925 ( R-HSA-75205 ) R-HSA-158925 Reaction Name: plasminogen:histidine-rich glycoprotein -> plasmin + histidine-rich glycoprotein (uPA [two-chain] catalyst) See in Reactome R-HSA-158942 ( R-HSA-75205 ) R-HSA-158942 Reaction Name: urokinase plasminogen activator (one-chain):uPAR -> urokinase plasminogen activator (two-chain):uPAR See in Reactome R-HSA-158959 ( R-HSA-75205 ) R-HSA-158959 Reaction Name: urokinase plasminogen activator + urokinase plasminogen activator receptor (uPAR) -> urokinase plasminogen activator:uPAR See in Reactome R-HSA-158982 ( R-HSA-75205 ) R-HSA-158982 Reaction Name: plasminogen:histidine-rich glycoprotein -> plasmin + histidine-rich glycoprotein (uPA [one-chain] catalyst) See in Reactome R-HSA-159001 ( R-HSA-75205 ) R-HSA-159001 Reaction Name: urokinase plasminogen activator (two-chain):uPAR + plasminogen activator inhibitor 2 (PAI-2) -> PAI-2:urokinase plasminogen activator (two-chain):uPAR See in Reactome R-HSA-159005 ( R-HSA-75205 ) R-HSA-159005 Reaction Name: urokinase plasminogen activator (two-chain):uPAR + plasminogen activator inhibitor 1 (PAI-1) -> PAI-1:urokinase plasminogen activator (two-chain):uPAR See in Reactome R-HSA-6798747 ( R-HSA-6798695 ) R-HSA-6798747 Reaction Name: Exocytosis of tertiary granule membrane proteins See in Reactome R-HSA-6799350 ( R-HSA-6798695 ) R-HSA-6799350 Reaction Name: Exocytosis of specific granule membrane proteins See in Reactome