DAR - Bologna Biocomputing Group

Search summary (UniProt accession: P00746)

Number of enzymes:	1
Number of disease:	1
Number of reactomes:	3
Number of reactions:	5

Search results (UniProt accession: P00746)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0013487	CFD	P00746	3.4.21.46	R-HSA-6798695 R-HSA-6798695 Reactome Name: Neutrophil degranulation See in Reactome R-HSA-114608 R-HSA-114608 Reactome Name: Platelet degranulation See in Reactome R-HSA-173736 R-HSA-173736 Reactome Name: Alternative complement activation See in Reactome	R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-76002 R-HSA-76002 Reactome Name: Platelet activation, signaling and aggregation See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-76005 R-HSA-76005 Reactome Name: Response to elevated platelet cytosolic Ca2+ See in Reactome R-HSA-166658 R-HSA-166658 Reactome Name: Complement cascade See in Reactome R-HSA-166663 R-HSA-166663 Reactome Name: Initial triggering of complement See in Reactome R-HSA-109582 R-HSA-109582 Reactome Name: Hemostasis See in Reactome	Immune System Hemostasis	R-HSA-173745 ( R-HSA-173736 ) R-HSA-173745 Reaction Name: Factor D cleaves C3(H2O)-bound Factor B See in Reactome R-HSA-183122 ( R-HSA-173736 ) R-HSA-183122 Reaction Name: Factor D cleaves C3b-bound Factor B See in Reactome R-HSA-481007 ( R-HSA-114608 ) R-HSA-481007 Reaction Name: Exocytosis of platelet alpha granule contents See in Reactome R-HSA-6798748 ( R-HSA-6798695 ) R-HSA-6798748 Reaction Name: Exocytosis of secretory granule lumen proteins See in Reactome R-HSA-6800434 ( R-HSA-6798695 ) R-HSA-6800434 Reaction Name: Exocytosis of ficolin-rich granule lumen proteins See in Reactome