DAR - Bologna Biocomputing Group

Search summary (UniProt accession: P00505)

Number of enzymes:	1
Number of disease:	1
Number of reactomes:	5
Number of reactions:	4

Search results (UniProt accession: P00505)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0032880	GOT2	P00505	2.6.1.7 2.6.1.1	R-HSA-389661 R-HSA-389661 Reactome Name: Glyoxylate metabolism and glycine degradation See in Reactome R-HSA-8964539 R-HSA-8964539 Reactome Name: Glutamate and glutamine metabolism See in Reactome R-HSA-1614558 R-HSA-1614558 Reactome Name: Degradation of cysteine and homocysteine See in Reactome R-HSA-8963693 R-HSA-8963693 Reactome Name: Aspartate and asparagine metabolism See in Reactome R-HSA-70263 R-HSA-70263 Reactome Name: Gluconeogenesis See in Reactome	R-HSA-71291 R-HSA-71291 Reactome Name: Metabolism of amino acids and derivatives See in Reactome R-HSA-1614635 R-HSA-1614635 Reactome Name: Sulfur amino acid metabolism See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-70326 R-HSA-70326 Reactome Name: Glucose metabolism See in Reactome R-HSA-71387 R-HSA-71387 Reactome Name: Metabolism of carbohydrates See in Reactome	Metabolism	R-HSA-6784393 ( R-HSA-389661 ) R-HSA-6784393 Reaction Name: PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) See in Reactome R-HSA-70596 ( R-HSA-8963693 ) R-HSA-70596 Reaction Name: GOT2 dimer deaminates L-Asp See in Reactome R-HSA-70613 ( R-HSA-70263; R-HSA-8964539 ) R-HSA-70613 Reaction Name: oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2] See in Reactome R-HSA-9012597 ( R-HSA-1614558 ) R-HSA-9012597 Reaction Name: GOT2 dimer transfers amino group from L-Cys to 2OG to form 3MPYR and Glu See in Reactome