DAR - Bologna Biocomputing Group

Search summary (UniProt accession: P00390)

Number of enzymes:	1
Number of disease:	1
Number of reactomes:	4
Number of reactions:	4

Search results (UniProt accession: P00390)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0019531	GSR	P00390	1.8.1.7	R-HSA-499943 R-HSA-499943 Reactome Name: Interconversion of nucleotide di- and triphosphates See in Reactome R-HSA-3299685 R-HSA-3299685 Reactome Name: Detoxification of Reactive Oxygen Species See in Reactome R-HSA-5628897 R-HSA-5628897 Reactome Name: TP53 Regulates Metabolic Genes See in Reactome R-HSA-2408550 R-HSA-2408550 Reactome Name: Metabolism of ingested H2SeO4 and H2SeO3 into H2Se See in Reactome	R-HSA-3700989 R-HSA-3700989 Reactome Name: Transcriptional Regulation by TP53 See in Reactome R-HSA-8953897 R-HSA-8953897 Reactome Name: Cellular responses to stimuli See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-71291 R-HSA-71291 Reactome Name: Metabolism of amino acids and derivatives See in Reactome R-HSA-2262752 R-HSA-2262752 Reactome Name: Cellular responses to stress See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-9711123 R-HSA-9711123 Reactome Name: Cellular response to chemical stress See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-15869 R-HSA-15869 Reactome Name: Metabolism of nucleotides See in Reactome R-HSA-2408522 R-HSA-2408522 Reactome Name: Selenoamino acid metabolism See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome	Cellular responses to stimuli Metabolism Gene expression (Transcription)	R-HSA-2408542 ( R-HSA-2408550 ) R-HSA-2408542 Reaction Name: GSSeSG is reduced to GSSeH and GSH by GSR See in Reactome R-HSA-3323079 ( R-HSA-3299685 ) R-HSA-3323079 Reaction Name: GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ See in Reactome R-HSA-71682 ( R-HSA-3299685; R-HSA-499943; R-HSA-5628897 ) R-HSA-71682 Reaction Name: glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ See in Reactome R-HSA-9761843 () R-HSA-9761843 Reaction Name: NFE2L2-dependent GSR gene expression See in Reactome