DAR - Bologna Biocomputing Group

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0007154	MAP4K4	O95819	2.7.11.1	R-HSA-2559580 R-HSA-2559580 Reactome Name: Oxidative Stress Induced Senescence See in Reactome	R-HSA-8953897 R-HSA-8953897 Reactome Name: Cellular responses to stimuli See in Reactome R-HSA-2262752 R-HSA-2262752 Reactome Name: Cellular responses to stress See in Reactome R-HSA-2559583 R-HSA-2559583 Reactome Name: Cellular Senescence See in Reactome	Cellular responses to stimuli	R-HSA-3225851 ( R-HSA-2559580 ) R-HSA-3225851 Reaction Name: ROS oxidize thioredoxin and activate MAP3K5 See in Reactome R-HSA-3225867 ( R-HSA-2559580 ) R-HSA-3225867 Reaction Name: Expression of MINK1/TNIK is positively regulated by ROS See in Reactome