DAR - Bologna Biocomputing Group

Search summary (UniProt accession: O75881)

Number of enzymes:	1
Number of disease:	2
Number of reactomes:	4
Number of reactions:	3

Search results (UniProt accession: O75881)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0010047	CYP7B1	O75881	1.14.14.26 1.14.14.29	R-HSA-211976 R-HSA-211976 Reactome Name: Endogenous sterols See in Reactome R-HSA-193807 R-HSA-193807 Reactome Name: Synthesis of bile acids and bile salts via 27-hydroxycholesterol See in Reactome R-HSA-193368 R-HSA-193368 Reactome Name: Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol See in Reactome R-HSA-192105 R-HSA-192105 Reactome Name: Synthesis of bile acids and bile salts See in Reactome	R-HSA-194068 R-HSA-194068 Reactome Name: Bile acid and bile salt metabolism See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-211897 R-HSA-211897 Reactome Name: Cytochrome P450 - arranged by substrate type See in Reactome R-HSA-211945 R-HSA-211945 Reactome Name: Phase I - Functionalization of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome	Metabolism	R-HSA-191972 ( R-HSA-192105; R-HSA-193807 ) R-HSA-191972 Reaction Name: 27-hydroxycholesterol is 7alpha-hydroxylated See in Reactome R-HSA-192051 ( R-HSA-192105; R-HSA-193368; R-HSA-211976 ) R-HSA-192051 Reaction Name: CYP7A1 7-hydroxylates CHOL See in Reactome R-HSA-192065 ( R-HSA-192105; R-HSA-211976 ) R-HSA-192065 Reaction Name: CYP7B1 7-hydroxylates 25OH-CHOL See in Reactome
MONDO:0013439	CYP7B1	O75881	1.14.14.26 1.14.14.29	R-HSA-211976 R-HSA-211976 Reactome Name: Endogenous sterols See in Reactome R-HSA-193807 R-HSA-193807 Reactome Name: Synthesis of bile acids and bile salts via 27-hydroxycholesterol See in Reactome R-HSA-193368 R-HSA-193368 Reactome Name: Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol See in Reactome R-HSA-192105 R-HSA-192105 Reactome Name: Synthesis of bile acids and bile salts See in Reactome	R-HSA-194068 R-HSA-194068 Reactome Name: Bile acid and bile salt metabolism See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-211897 R-HSA-211897 Reactome Name: Cytochrome P450 - arranged by substrate type See in Reactome R-HSA-211945 R-HSA-211945 Reactome Name: Phase I - Functionalization of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome	Metabolism	R-HSA-191972 ( R-HSA-192105; R-HSA-193807 ) R-HSA-191972 Reaction Name: 27-hydroxycholesterol is 7alpha-hydroxylated See in Reactome R-HSA-192051 ( R-HSA-192105; R-HSA-193368; R-HSA-211976 ) R-HSA-192051 Reaction Name: CYP7A1 7-hydroxylates CHOL See in Reactome R-HSA-192065 ( R-HSA-192105; R-HSA-211976 ) R-HSA-192065 Reaction Name: CYP7B1 7-hydroxylates 25OH-CHOL See in Reactome