DAR - Bologna Biocomputing Group

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0011816	SC5D	O75845	1.14.19.20	R-HSA-6807062 R-HSA-6807062 Reactome Name: Cholesterol biosynthesis via lathosterol See in Reactome R-HSA-2426168 R-HSA-2426168 Reactome Name: Activation of gene expression by SREBF (SREBP) See in Reactome R-HSA-6807047 R-HSA-6807047 Reactome Name: Cholesterol biosynthesis via desmosterol See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-1655829 R-HSA-1655829 Reactome Name: Regulation of cholesterol biosynthesis by SREBP (SREBF) See in Reactome R-HSA-191273 R-HSA-191273 Reactome Name: Cholesterol biosynthesis See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome	Metabolism	R-HSA-1655852 ( R-HSA-2426168 ) R-HSA-1655852 Reaction Name: Expression of Lathosterol Oxidase (SC5D, SC5DL) See in Reactome R-HSA-195664 ( R-HSA-6807047 ) R-HSA-195664 Reaction Name: Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol See in Reactome R-HSA-6807053 ( R-HSA-6807062 ) R-HSA-6807053 Reaction Name: SC5D desaturates LTHSOL to 7-dehydroCHOL See in Reactome