DAR - Bologna Biocomputing Group

Search summary (UniProt accession: O60733)

Number of enzymes:	1
Number of disease:	7
Number of reactomes:	5
Number of reactions:	5

Search results (UniProt accession: O60733)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0001149	PLA2G6	O60733	3.1.1.4 3.1.1.5 3.1.2.2	R-HSA-1482798 R-HSA-1482798 Reactome Name: Acyl chain remodeling of CL See in Reactome R-HSA-1482839 R-HSA-1482839 Reactome Name: Acyl chain remodelling of PE See in Reactome R-HSA-6811436 R-HSA-6811436 Reactome Name: COPI-independent Golgi-to-ER retrograde traffic See in Reactome R-HSA-2029485 R-HSA-2029485 Reactome Name: Role of phospholipids in phagocytosis See in Reactome R-HSA-1482788 R-HSA-1482788 Reactome Name: Acyl chain remodelling of PC See in Reactome	R-HSA-2029480 R-HSA-2029480 Reactome Name: Fcgamma receptor (FCGR) dependent phagocytosis See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-8856688 R-HSA-8856688 Reactome Name: Golgi-to-ER retrograde transport See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-1483257 R-HSA-1483257 Reactome Name: Phospholipid metabolism See in Reactome R-HSA-6811442 R-HSA-6811442 Reactome Name: Intra-Golgi and retrograde Golgi-to-ER traffic See in Reactome R-HSA-199991 R-HSA-199991 Reactome Name: Membrane Trafficking See in Reactome R-HSA-1483206 R-HSA-1483206 Reactome Name: Glycerophospholipid biosynthesis See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-5653656 R-HSA-5653656 Reactome Name: Vesicle-mediated transport See in Reactome	Immune System Metabolism Vesicle-mediated transport	R-HSA-1482778 ( R-HSA-1482798 ) R-HSA-1482778 Reaction Name: CL is hydrolyzed to MLCL by PLA2G6 (IM) See in Reactome R-HSA-1482856 ( R-HSA-1482788 ) R-HSA-1482856 Reaction Name: PC is hydrolyzed to 1-acyl LPC by PLA2[5] See in Reactome R-HSA-1482884 ( R-HSA-1482839 ) R-HSA-1482884 Reaction Name: PE is hydrolyzed to 1-acyl LPE by PLA2[2] See in Reactome R-HSA-2029475 ( R-HSA-2029485 ) R-HSA-2029475 Reaction Name: Production of AA by iPLA2 upon FCGR activation See in Reactome R-HSA-8848484 ( R-HSA-6811436 ) R-HSA-8848484 Reaction Name: PLA2s hydrolyze phospholipids at the Golgi membrane See in Reactome
MONDO:0013060	PLA2G6	O60733	3.1.1.4 3.1.1.5 3.1.2.2	R-HSA-1482798 R-HSA-1482798 Reactome Name: Acyl chain remodeling of CL See in Reactome R-HSA-1482839 R-HSA-1482839 Reactome Name: Acyl chain remodelling of PE See in Reactome R-HSA-6811436 R-HSA-6811436 Reactome Name: COPI-independent Golgi-to-ER retrograde traffic See in Reactome R-HSA-2029485 R-HSA-2029485 Reactome Name: Role of phospholipids in phagocytosis See in Reactome R-HSA-1482788 R-HSA-1482788 Reactome Name: Acyl chain remodelling of PC See in Reactome	R-HSA-2029480 R-HSA-2029480 Reactome Name: Fcgamma receptor (FCGR) dependent phagocytosis See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-8856688 R-HSA-8856688 Reactome Name: Golgi-to-ER retrograde transport See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-1483257 R-HSA-1483257 Reactome Name: Phospholipid metabolism See in Reactome R-HSA-6811442 R-HSA-6811442 Reactome Name: Intra-Golgi and retrograde Golgi-to-ER traffic See in Reactome R-HSA-199991 R-HSA-199991 Reactome Name: Membrane Trafficking See in Reactome R-HSA-1483206 R-HSA-1483206 Reactome Name: Glycerophospholipid biosynthesis See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-5653656 R-HSA-5653656 Reactome Name: Vesicle-mediated transport See in Reactome	Immune System Metabolism Vesicle-mediated transport	R-HSA-1482778 ( R-HSA-1482798 ) R-HSA-1482778 Reaction Name: CL is hydrolyzed to MLCL by PLA2G6 (IM) See in Reactome R-HSA-1482856 ( R-HSA-1482788 ) R-HSA-1482856 Reaction Name: PC is hydrolyzed to 1-acyl LPC by PLA2[5] See in Reactome R-HSA-1482884 ( R-HSA-1482839 ) R-HSA-1482884 Reaction Name: PE is hydrolyzed to 1-acyl LPE by PLA2[2] See in Reactome R-HSA-2029475 ( R-HSA-2029485 ) R-HSA-2029475 Reaction Name: Production of AA by iPLA2 upon FCGR activation See in Reactome R-HSA-8848484 ( R-HSA-6811436 ) R-HSA-8848484 Reaction Name: PLA2s hydrolyze phospholipids at the Golgi membrane See in Reactome
MONDO:0024457	PLA2G6	O60733	3.1.1.4 3.1.1.5 3.1.2.2	R-HSA-1482798 R-HSA-1482798 Reactome Name: Acyl chain remodeling of CL See in Reactome R-HSA-1482839 R-HSA-1482839 Reactome Name: Acyl chain remodelling of PE See in Reactome R-HSA-6811436 R-HSA-6811436 Reactome Name: COPI-independent Golgi-to-ER retrograde traffic See in Reactome R-HSA-2029485 R-HSA-2029485 Reactome Name: Role of phospholipids in phagocytosis See in Reactome R-HSA-1482788 R-HSA-1482788 Reactome Name: Acyl chain remodelling of PC See in Reactome	R-HSA-2029480 R-HSA-2029480 Reactome Name: Fcgamma receptor (FCGR) dependent phagocytosis See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-8856688 R-HSA-8856688 Reactome Name: Golgi-to-ER retrograde transport See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-1483257 R-HSA-1483257 Reactome Name: Phospholipid metabolism See in Reactome R-HSA-6811442 R-HSA-6811442 Reactome Name: Intra-Golgi and retrograde Golgi-to-ER traffic See in Reactome R-HSA-199991 R-HSA-199991 Reactome Name: Membrane Trafficking See in Reactome R-HSA-1483206 R-HSA-1483206 Reactome Name: Glycerophospholipid biosynthesis See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-5653656 R-HSA-5653656 Reactome Name: Vesicle-mediated transport See in Reactome	Immune System Metabolism Vesicle-mediated transport	R-HSA-1482778 ( R-HSA-1482798 ) R-HSA-1482778 Reaction Name: CL is hydrolyzed to MLCL by PLA2G6 (IM) See in Reactome R-HSA-1482856 ( R-HSA-1482788 ) R-HSA-1482856 Reaction Name: PC is hydrolyzed to 1-acyl LPC by PLA2[5] See in Reactome R-HSA-1482884 ( R-HSA-1482839 ) R-HSA-1482884 Reaction Name: PE is hydrolyzed to 1-acyl LPE by PLA2[2] See in Reactome R-HSA-2029475 ( R-HSA-2029485 ) R-HSA-2029475 Reaction Name: Production of AA by iPLA2 upon FCGR activation See in Reactome R-HSA-8848484 ( R-HSA-6811436 ) R-HSA-8848484 Reaction Name: PLA2s hydrolyze phospholipids at the Golgi membrane See in Reactome
MONDO:0000437	PLA2G6	O60733	3.1.1.4 3.1.1.5 3.1.2.2	R-HSA-1482798 R-HSA-1482798 Reactome Name: Acyl chain remodeling of CL See in Reactome R-HSA-1482839 R-HSA-1482839 Reactome Name: Acyl chain remodelling of PE See in Reactome R-HSA-6811436 R-HSA-6811436 Reactome Name: COPI-independent Golgi-to-ER retrograde traffic See in Reactome R-HSA-2029485 R-HSA-2029485 Reactome Name: Role of phospholipids in phagocytosis See in Reactome R-HSA-1482788 R-HSA-1482788 Reactome Name: Acyl chain remodelling of PC See in Reactome	R-HSA-2029480 R-HSA-2029480 Reactome Name: Fcgamma receptor (FCGR) dependent phagocytosis See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-8856688 R-HSA-8856688 Reactome Name: Golgi-to-ER retrograde transport See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-1483257 R-HSA-1483257 Reactome Name: Phospholipid metabolism See in Reactome R-HSA-6811442 R-HSA-6811442 Reactome Name: Intra-Golgi and retrograde Golgi-to-ER traffic See in Reactome R-HSA-199991 R-HSA-199991 Reactome Name: Membrane Trafficking See in Reactome R-HSA-1483206 R-HSA-1483206 Reactome Name: Glycerophospholipid biosynthesis See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-5653656 R-HSA-5653656 Reactome Name: Vesicle-mediated transport See in Reactome	Immune System Metabolism Vesicle-mediated transport	R-HSA-1482778 ( R-HSA-1482798 ) R-HSA-1482778 Reaction Name: CL is hydrolyzed to MLCL by PLA2G6 (IM) See in Reactome R-HSA-1482856 ( R-HSA-1482788 ) R-HSA-1482856 Reaction Name: PC is hydrolyzed to 1-acyl LPC by PLA2[5] See in Reactome R-HSA-1482884 ( R-HSA-1482839 ) R-HSA-1482884 Reaction Name: PE is hydrolyzed to 1-acyl LPE by PLA2[2] See in Reactome R-HSA-2029475 ( R-HSA-2029485 ) R-HSA-2029475 Reaction Name: Production of AA by iPLA2 upon FCGR activation See in Reactome R-HSA-8848484 ( R-HSA-6811436 ) R-HSA-8848484 Reaction Name: PLA2s hydrolyze phospholipids at the Golgi membrane See in Reactome
MONDO:0008939	PLA2G6	O60733	3.1.1.4 3.1.1.5 3.1.2.2	R-HSA-1482798 R-HSA-1482798 Reactome Name: Acyl chain remodeling of CL See in Reactome R-HSA-1482839 R-HSA-1482839 Reactome Name: Acyl chain remodelling of PE See in Reactome R-HSA-6811436 R-HSA-6811436 Reactome Name: COPI-independent Golgi-to-ER retrograde traffic See in Reactome R-HSA-2029485 R-HSA-2029485 Reactome Name: Role of phospholipids in phagocytosis See in Reactome R-HSA-1482788 R-HSA-1482788 Reactome Name: Acyl chain remodelling of PC See in Reactome	R-HSA-2029480 R-HSA-2029480 Reactome Name: Fcgamma receptor (FCGR) dependent phagocytosis See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-8856688 R-HSA-8856688 Reactome Name: Golgi-to-ER retrograde transport See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-1483257 R-HSA-1483257 Reactome Name: Phospholipid metabolism See in Reactome R-HSA-6811442 R-HSA-6811442 Reactome Name: Intra-Golgi and retrograde Golgi-to-ER traffic See in Reactome R-HSA-199991 R-HSA-199991 Reactome Name: Membrane Trafficking See in Reactome R-HSA-1483206 R-HSA-1483206 Reactome Name: Glycerophospholipid biosynthesis See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-5653656 R-HSA-5653656 Reactome Name: Vesicle-mediated transport See in Reactome	Immune System Metabolism Vesicle-mediated transport	R-HSA-1482778 ( R-HSA-1482798 ) R-HSA-1482778 Reaction Name: CL is hydrolyzed to MLCL by PLA2G6 (IM) See in Reactome R-HSA-1482856 ( R-HSA-1482788 ) R-HSA-1482856 Reaction Name: PC is hydrolyzed to 1-acyl LPC by PLA2[5] See in Reactome R-HSA-1482884 ( R-HSA-1482839 ) R-HSA-1482884 Reaction Name: PE is hydrolyzed to 1-acyl LPE by PLA2[2] See in Reactome R-HSA-2029475 ( R-HSA-2029485 ) R-HSA-2029475 Reaction Name: Production of AA by iPLA2 upon FCGR activation See in Reactome R-HSA-8848484 ( R-HSA-6811436 ) R-HSA-8848484 Reaction Name: PLA2s hydrolyze phospholipids at the Golgi membrane See in Reactome
MONDO:0012444	PLA2G6	O60733	3.1.1.4 3.1.1.5 3.1.2.2	R-HSA-1482798 R-HSA-1482798 Reactome Name: Acyl chain remodeling of CL See in Reactome R-HSA-1482839 R-HSA-1482839 Reactome Name: Acyl chain remodelling of PE See in Reactome R-HSA-6811436 R-HSA-6811436 Reactome Name: COPI-independent Golgi-to-ER retrograde traffic See in Reactome R-HSA-2029485 R-HSA-2029485 Reactome Name: Role of phospholipids in phagocytosis See in Reactome R-HSA-1482788 R-HSA-1482788 Reactome Name: Acyl chain remodelling of PC See in Reactome	R-HSA-2029480 R-HSA-2029480 Reactome Name: Fcgamma receptor (FCGR) dependent phagocytosis See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-8856688 R-HSA-8856688 Reactome Name: Golgi-to-ER retrograde transport See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-1483257 R-HSA-1483257 Reactome Name: Phospholipid metabolism See in Reactome R-HSA-6811442 R-HSA-6811442 Reactome Name: Intra-Golgi and retrograde Golgi-to-ER traffic See in Reactome R-HSA-199991 R-HSA-199991 Reactome Name: Membrane Trafficking See in Reactome R-HSA-1483206 R-HSA-1483206 Reactome Name: Glycerophospholipid biosynthesis See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-5653656 R-HSA-5653656 Reactome Name: Vesicle-mediated transport See in Reactome	Immune System Metabolism Vesicle-mediated transport	R-HSA-1482778 ( R-HSA-1482798 ) R-HSA-1482778 Reaction Name: CL is hydrolyzed to MLCL by PLA2G6 (IM) See in Reactome R-HSA-1482856 ( R-HSA-1482788 ) R-HSA-1482856 Reaction Name: PC is hydrolyzed to 1-acyl LPC by PLA2[5] See in Reactome R-HSA-1482884 ( R-HSA-1482839 ) R-HSA-1482884 Reaction Name: PE is hydrolyzed to 1-acyl LPE by PLA2[2] See in Reactome R-HSA-2029475 ( R-HSA-2029485 ) R-HSA-2029475 Reaction Name: Production of AA by iPLA2 upon FCGR activation See in Reactome R-HSA-8848484 ( R-HSA-6811436 ) R-HSA-8848484 Reaction Name: PLA2s hydrolyze phospholipids at the Golgi membrane See in Reactome
MONDO:0016392	PLA2G6	O60733	3.1.1.4 3.1.1.5 3.1.2.2	R-HSA-1482798 R-HSA-1482798 Reactome Name: Acyl chain remodeling of CL See in Reactome R-HSA-1482839 R-HSA-1482839 Reactome Name: Acyl chain remodelling of PE See in Reactome R-HSA-6811436 R-HSA-6811436 Reactome Name: COPI-independent Golgi-to-ER retrograde traffic See in Reactome R-HSA-2029485 R-HSA-2029485 Reactome Name: Role of phospholipids in phagocytosis See in Reactome R-HSA-1482788 R-HSA-1482788 Reactome Name: Acyl chain remodelling of PC See in Reactome	R-HSA-2029480 R-HSA-2029480 Reactome Name: Fcgamma receptor (FCGR) dependent phagocytosis See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-8856688 R-HSA-8856688 Reactome Name: Golgi-to-ER retrograde transport See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-1483257 R-HSA-1483257 Reactome Name: Phospholipid metabolism See in Reactome R-HSA-6811442 R-HSA-6811442 Reactome Name: Intra-Golgi and retrograde Golgi-to-ER traffic See in Reactome R-HSA-199991 R-HSA-199991 Reactome Name: Membrane Trafficking See in Reactome R-HSA-1483206 R-HSA-1483206 Reactome Name: Glycerophospholipid biosynthesis See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-5653656 R-HSA-5653656 Reactome Name: Vesicle-mediated transport See in Reactome	Immune System Metabolism Vesicle-mediated transport	R-HSA-1482778 ( R-HSA-1482798 ) R-HSA-1482778 Reaction Name: CL is hydrolyzed to MLCL by PLA2G6 (IM) See in Reactome R-HSA-1482856 ( R-HSA-1482788 ) R-HSA-1482856 Reaction Name: PC is hydrolyzed to 1-acyl LPC by PLA2[5] See in Reactome R-HSA-1482884 ( R-HSA-1482839 ) R-HSA-1482884 Reaction Name: PE is hydrolyzed to 1-acyl LPE by PLA2[2] See in Reactome R-HSA-2029475 ( R-HSA-2029485 ) R-HSA-2029475 Reaction Name: Production of AA by iPLA2 upon FCGR activation See in Reactome R-HSA-8848484 ( R-HSA-6811436 ) R-HSA-8848484 Reaction Name: PLA2s hydrolyze phospholipids at the Golgi membrane See in Reactome