DAR - Bologna Biocomputing Group

Search summary (UniProt accession: O60673)

Number of enzymes:	1
Number of disease:	2
Number of reactomes:	3
Number of reactions:	9

Search results (UniProt accession: O60673)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0002032	REV3L	O60673	2.7.7.7	R-HSA-5656121 R-HSA-5656121 Reactome Name: Translesion synthesis by POLI See in Reactome R-HSA-5655862 R-HSA-5655862 Reactome Name: Translesion synthesis by POLK See in Reactome R-HSA-110312 R-HSA-110312 Reactome Name: Translesion synthesis by REV1 See in Reactome	R-HSA-73894 R-HSA-73894 Reactome Name: DNA Repair See in Reactome R-HSA-73893 R-HSA-73893 Reactome Name: DNA Damage Bypass See in Reactome R-HSA-110313 R-HSA-110313 Reactome Name: Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template See in Reactome	DNA Repair	R-HSA-110311 ( R-HSA-110312 ) R-HSA-110311 Reaction Name: POLZ extends translesion synthesis See in Reactome R-HSA-110322 ( R-HSA-110312 ) R-HSA-110322 Reaction Name: Formation of Pol zeta complex See in Reactome R-HSA-5652151 ( R-HSA-110312 ) R-HSA-5652151 Reaction Name: REV1 recruits POLZ to (AP:Cyt)-DNA Template See in Reactome R-HSA-5655835 ( R-HSA-5655862 ) R-HSA-5655835 Reaction Name: POLK forms a quaternary complex with REV1 and POLZ on damaged DNA template See in Reactome R-HSA-5655892 ( R-HSA-5655862 ) R-HSA-5655892 Reaction Name: POLK incorporates dNMP opposite to damaged DNA base See in Reactome R-HSA-5655965 ( R-HSA-5655862 ) R-HSA-5655965 Reaction Name: POLK and POLZ cooperate in elongation of mispaired primer termini See in Reactome R-HSA-5656105 ( R-HSA-5656121 ) R-HSA-5656105 Reaction Name: POLI simultaneously binds REV1 and monoUb:K164-PCNA at damaged DNA See in Reactome R-HSA-5656148 ( R-HSA-5656121 ) R-HSA-5656148 Reaction Name: POLI incorporates dNMP opposite to damaged DNA base See in Reactome R-HSA-5656158 ( R-HSA-5656121 ) R-HSA-5656158 Reaction Name: POLZ elongates POLI-incorporated dNMP See in Reactome
MONDO:0008006	REV3L	O60673	2.7.7.7	R-HSA-5656121 R-HSA-5656121 Reactome Name: Translesion synthesis by POLI See in Reactome R-HSA-5655862 R-HSA-5655862 Reactome Name: Translesion synthesis by POLK See in Reactome R-HSA-110312 R-HSA-110312 Reactome Name: Translesion synthesis by REV1 See in Reactome	R-HSA-73894 R-HSA-73894 Reactome Name: DNA Repair See in Reactome R-HSA-73893 R-HSA-73893 Reactome Name: DNA Damage Bypass See in Reactome R-HSA-110313 R-HSA-110313 Reactome Name: Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template See in Reactome	DNA Repair	R-HSA-110311 ( R-HSA-110312 ) R-HSA-110311 Reaction Name: POLZ extends translesion synthesis See in Reactome R-HSA-110322 ( R-HSA-110312 ) R-HSA-110322 Reaction Name: Formation of Pol zeta complex See in Reactome R-HSA-5652151 ( R-HSA-110312 ) R-HSA-5652151 Reaction Name: REV1 recruits POLZ to (AP:Cyt)-DNA Template See in Reactome R-HSA-5655835 ( R-HSA-5655862 ) R-HSA-5655835 Reaction Name: POLK forms a quaternary complex with REV1 and POLZ on damaged DNA template See in Reactome R-HSA-5655892 ( R-HSA-5655862 ) R-HSA-5655892 Reaction Name: POLK incorporates dNMP opposite to damaged DNA base See in Reactome R-HSA-5655965 ( R-HSA-5655862 ) R-HSA-5655965 Reaction Name: POLK and POLZ cooperate in elongation of mispaired primer termini See in Reactome R-HSA-5656105 ( R-HSA-5656121 ) R-HSA-5656105 Reaction Name: POLI simultaneously binds REV1 and monoUb:K164-PCNA at damaged DNA See in Reactome R-HSA-5656148 ( R-HSA-5656121 ) R-HSA-5656148 Reaction Name: POLI incorporates dNMP opposite to damaged DNA base See in Reactome R-HSA-5656158 ( R-HSA-5656121 ) R-HSA-5656158 Reaction Name: POLZ elongates POLI-incorporated dNMP See in Reactome