DAR - Bologna Biocomputing Group

Search summary (UniProt accession: O60488)

Number of enzymes:	1
Number of disease:	2
Number of reactomes:	2
Number of reactions:	2

Search results (UniProt accession: O60488)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0010263	ACSL4	O60488	6.2.1.15 6.2.1.3	R-HSA-75876 R-HSA-75876 Reactome Name: Synthesis of very long-chain fatty acyl-CoAs See in Reactome R-HSA-434313 R-HSA-434313 Reactome Name: Intracellular metabolism of fatty acids regulates insulin secretion See in Reactome	R-HSA-422356 R-HSA-422356 Reactome Name: Regulation of insulin secretion See in Reactome R-HSA-400451 R-HSA-400451 Reactome Name: Free fatty acids regulate insulin secretion See in Reactome R-HSA-75105 R-HSA-75105 Reactome Name: Fatty acyl-CoA biosynthesis See in Reactome R-HSA-163685 R-HSA-163685 Reactome Name: Integration of energy metabolism See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8978868 R-HSA-8978868 Reactome Name: Fatty acid metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome	Metabolism	R-HSA-434382 ( R-HSA-434313 ) R-HSA-434382 Reaction Name: ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell See in Reactome R-HSA-548843 ( R-HSA-75876 ) R-HSA-548843 Reaction Name: ACSL3,4 ligate CoA to AA to form AA-CoA See in Reactome
MONDO:0010313	ACSL4	O60488	6.2.1.15 6.2.1.3	R-HSA-75876 R-HSA-75876 Reactome Name: Synthesis of very long-chain fatty acyl-CoAs See in Reactome R-HSA-434313 R-HSA-434313 Reactome Name: Intracellular metabolism of fatty acids regulates insulin secretion See in Reactome	R-HSA-422356 R-HSA-422356 Reactome Name: Regulation of insulin secretion See in Reactome R-HSA-400451 R-HSA-400451 Reactome Name: Free fatty acids regulate insulin secretion See in Reactome R-HSA-75105 R-HSA-75105 Reactome Name: Fatty acyl-CoA biosynthesis See in Reactome R-HSA-163685 R-HSA-163685 Reactome Name: Integration of energy metabolism See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8978868 R-HSA-8978868 Reactome Name: Fatty acid metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome	Metabolism	R-HSA-434382 ( R-HSA-434313 ) R-HSA-434382 Reaction Name: ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell See in Reactome R-HSA-548843 ( R-HSA-75876 ) R-HSA-548843 Reaction Name: ACSL3,4 ligate CoA to AA to form AA-CoA See in Reactome