DAR - Bologna Biocomputing Group

Search summary (UniProt accession: O00443)

Number of enzymes:	1
Number of disease:	1
Number of reactomes:	6
Number of reactions:	13

Search results (UniProt accession: O00443)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0034145	PIK3C2A	O00443	2.7.1.137 2.7.1.154 2.7.1.153	R-HSA-1660499 R-HSA-1660499 Reactome Name: Synthesis of PIPs at the plasma membrane See in Reactome R-HSA-1660514 R-HSA-1660514 Reactome Name: Synthesis of PIPs at the Golgi membrane See in Reactome R-HSA-1660516 R-HSA-1660516 Reactome Name: Synthesis of PIPs at the early endosome membrane See in Reactome R-HSA-1660517 R-HSA-1660517 Reactome Name: Synthesis of PIPs at the late endosome membrane See in Reactome R-HSA-8856828 R-HSA-8856828 Reactome Name: Clathrin-mediated endocytosis See in Reactome R-HSA-432722 R-HSA-432722 Reactome Name: Golgi Associated Vesicle Biogenesis See in Reactome	R-HSA-1483257 R-HSA-1483257 Reactome Name: Phospholipid metabolism See in Reactome R-HSA-1483255 R-HSA-1483255 Reactome Name: PI Metabolism See in Reactome R-HSA-199991 R-HSA-199991 Reactome Name: Membrane Trafficking See in Reactome R-HSA-199992 R-HSA-199992 Reactome Name: trans-Golgi Network Vesicle Budding See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-5653656 R-HSA-5653656 Reactome Name: Vesicle-mediated transport See in Reactome	Metabolism Vesicle-mediated transport	R-HSA-1675928 ( R-HSA-1660514 ) R-HSA-1675928 Reaction Name: PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane See in Reactome R-HSA-1675939 ( R-HSA-1660516 ) R-HSA-1675939 Reaction Name: PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane See in Reactome R-HSA-1675961 ( R-HSA-1660514 ) R-HSA-1675961 Reaction Name: PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane See in Reactome R-HSA-1676024 ( R-HSA-1660517 ) R-HSA-1676024 Reaction Name: PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane See in Reactome R-HSA-1676109 ( R-HSA-1660499 ) R-HSA-1676109 Reaction Name: PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane See in Reactome R-HSA-1676206 ( R-HSA-1660516 ) R-HSA-1676206 Reaction Name: PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane See in Reactome R-HSA-421831 ( R-HSA-432722 ) R-HSA-421831 Reaction Name: trans-Golgi Network Coat Assembly See in Reactome R-HSA-421833 ( R-HSA-432722 ) R-HSA-421833 Reaction Name: Vamp And trans-Golgi Network AP-1 Binding Coupled With Cargo Capture See in Reactome R-HSA-421835 ( R-HSA-432722 ) R-HSA-421835 Reaction Name: trans-Golgi Network Vesicle Scission See in Reactome R-HSA-421836 ( R-HSA-432722 ) R-HSA-421836 Reaction Name: trans-Golgi Network Derived Vesicle Uncoating See in Reactome R-HSA-8867754 ( R-HSA-8856828 ) R-HSA-8867754 Reaction Name: F- and N- BAR domain proteins bind the clathrin-coated pit See in Reactome R-HSA-8868071 ( R-HSA-8856828 ) R-HSA-8868071 Reaction Name: Clathrin recruits PIK3C2A See in Reactome R-HSA-8868072 ( R-HSA-8856828 ) R-HSA-8868072 Reaction Name: Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 See in Reactome