DAR - Bologna Biocomputing Group

Search summary (UniProt accession: O00187)

Number of enzymes:	1
Number of disease:	1
Number of reactomes:	3
Number of reactions:	8

Search results (UniProt accession: O00187)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0013423	MASP2	O00187	3.4.21.104	R-HSA-2855086 R-HSA-2855086 Reactome Name: Ficolins bind to repetitive carbohydrate structures on the target cell surface See in Reactome R-HSA-166663 R-HSA-166663 Reactome Name: Initial triggering of complement See in Reactome R-HSA-166662 R-HSA-166662 Reactome Name: Lectin pathway of complement activation See in Reactome	R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-166786 R-HSA-166786 Reactome Name: Creation of C4 and C2 activators See in Reactome R-HSA-166658 R-HSA-166658 Reactome Name: Complement cascade See in Reactome	Immune System	R-HSA-166721 ( R-HSA-166662; R-HSA-166663 ) R-HSA-166721 Reaction Name: MBL binds to repetitive carbohydrate structures on the surfaces of viruses, bacteria, fungi, and protozoa See in Reactome R-HSA-166726 ( R-HSA-166662; R-HSA-166663 ) R-HSA-166726 Reaction Name: Activation of MASPs See in Reactome R-HSA-166753 ( R-HSA-166663 ) R-HSA-166753 Reaction Name: Conversion of C4 into C4a and C4b See in Reactome R-HSA-166792 ( R-HSA-166663 ) R-HSA-166792 Reaction Name: Conversion of C2 into C2a and C2b See in Reactome R-HSA-2855054 ( R-HSA-166662; R-HSA-166663; R-HSA-2855086 ) R-HSA-2855054 Reaction Name: Ficolin-2 binds to molecular patterns on the target cell surface See in Reactome R-HSA-2855077 ( R-HSA-166662; R-HSA-166663; R-HSA-2855086 ) R-HSA-2855077 Reaction Name: Ficolin-3 binds to molecular patterns on the target cell surface See in Reactome R-HSA-2855125 ( R-HSA-166662; R-HSA-166663; R-HSA-2855086 ) R-HSA-2855125 Reaction Name: Ficolin-1 binds to molecular patterns on the target cell surface See in Reactome R-HSA-8852509 ( R-HSA-166662; R-HSA-166663 ) R-HSA-8852509 Reaction Name: CL-LK binds carbohydrates on target cell surface See in Reactome