DAR - Bologna Biocomputing Group

Search summary (UniProt accession: O00141)

Number of enzymes:	1
Number of disease:	2
Number of reactomes:	4
Number of reactions:	7

Search results (UniProt accession: O00141)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0019438	SGK1	O00141	2.7.11.1	R-HSA-6804757 R-HSA-6804757 Reactome Name: Regulation of TP53 Degradation See in Reactome R-HSA-8986944 R-HSA-8986944 Reactome Name: Transcriptional Regulation by MECP2 See in Reactome R-HSA-9031628 R-HSA-9031628 Reactome Name: NGF-stimulated transcription See in Reactome R-HSA-2672351 R-HSA-2672351 Reactome Name: Stimuli-sensing channels See in Reactome	R-HSA-3700989 R-HSA-3700989 Reactome Name: Transcriptional Regulation by TP53 See in Reactome R-HSA-5633007 R-HSA-5633007 Reactome Name: Regulation of TP53 Activity See in Reactome R-HSA-166520 R-HSA-166520 Reactome Name: Signaling by NTRKs See in Reactome R-HSA-6806003 R-HSA-6806003 Reactome Name: Regulation of TP53 Expression and Degradation See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-983712 R-HSA-983712 Reactome Name: Ion channel transport See in Reactome R-HSA-382551 R-HSA-382551 Reactome Name: Transport of small molecules See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-9006934 R-HSA-9006934 Reactome Name: Signaling by Receptor Tyrosine Kinases See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-198725 R-HSA-198725 Reactome Name: Nuclear Events (kinase and transcription factor activation) See in Reactome R-HSA-187037 R-HSA-187037 Reactome Name: Signaling by NTRK1 (TRKA) See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome	Gene expression (Transcription) Transport of small molecules Signal Transduction	R-HSA-2682349 ( R-HSA-2672351 ) R-HSA-2682349 Reaction Name: RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels See in Reactome R-HSA-6795290 ( R-HSA-6804757 ) R-HSA-6795290 Reaction Name: TORC2 complex phosphorylates SGK1 See in Reactome R-HSA-6795460 ( R-HSA-6804757 ) R-HSA-6795460 Reaction Name: SGK1 phosphorylates MDM2 See in Reactome R-HSA-6795473 ( R-HSA-6804757 ) R-HSA-6795473 Reaction Name: PDPK1 phosphorylates SGK1 See in Reactome R-HSA-9022764 ( R-HSA-8986944 ) R-HSA-9022764 Reaction Name: SGK1 gene expression is inhibited by MECP2 See in Reactome R-HSA-9612501 ( R-HSA-9031628 ) R-HSA-9612501 Reaction Name: SGK phosphorylates CREB1 See in Reactome R-HSA-9612509 ( R-HSA-9031628 ) R-HSA-9612509 Reaction Name: SGK phosphorylates SRF See in Reactome
MONDO:0009693	SGK1	O00141	2.7.11.1	R-HSA-6804757 R-HSA-6804757 Reactome Name: Regulation of TP53 Degradation See in Reactome R-HSA-8986944 R-HSA-8986944 Reactome Name: Transcriptional Regulation by MECP2 See in Reactome R-HSA-9031628 R-HSA-9031628 Reactome Name: NGF-stimulated transcription See in Reactome R-HSA-2672351 R-HSA-2672351 Reactome Name: Stimuli-sensing channels See in Reactome	R-HSA-3700989 R-HSA-3700989 Reactome Name: Transcriptional Regulation by TP53 See in Reactome R-HSA-5633007 R-HSA-5633007 Reactome Name: Regulation of TP53 Activity See in Reactome R-HSA-166520 R-HSA-166520 Reactome Name: Signaling by NTRKs See in Reactome R-HSA-6806003 R-HSA-6806003 Reactome Name: Regulation of TP53 Expression and Degradation See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-983712 R-HSA-983712 Reactome Name: Ion channel transport See in Reactome R-HSA-382551 R-HSA-382551 Reactome Name: Transport of small molecules See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-9006934 R-HSA-9006934 Reactome Name: Signaling by Receptor Tyrosine Kinases See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-198725 R-HSA-198725 Reactome Name: Nuclear Events (kinase and transcription factor activation) See in Reactome R-HSA-187037 R-HSA-187037 Reactome Name: Signaling by NTRK1 (TRKA) See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome	Gene expression (Transcription) Transport of small molecules Signal Transduction	R-HSA-2682349 ( R-HSA-2672351 ) R-HSA-2682349 Reaction Name: RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels See in Reactome R-HSA-6795290 ( R-HSA-6804757 ) R-HSA-6795290 Reaction Name: TORC2 complex phosphorylates SGK1 See in Reactome R-HSA-6795460 ( R-HSA-6804757 ) R-HSA-6795460 Reaction Name: SGK1 phosphorylates MDM2 See in Reactome R-HSA-6795473 ( R-HSA-6804757 ) R-HSA-6795473 Reaction Name: PDPK1 phosphorylates SGK1 See in Reactome R-HSA-9022764 ( R-HSA-8986944 ) R-HSA-9022764 Reaction Name: SGK1 gene expression is inhibited by MECP2 See in Reactome R-HSA-9612501 ( R-HSA-9031628 ) R-HSA-9612501 Reaction Name: SGK phosphorylates CREB1 See in Reactome R-HSA-9612509 ( R-HSA-9031628 ) R-HSA-9612509 Reaction Name: SGK phosphorylates SRF See in Reactome