DAR - Bologna Biocomputing Group

Search results (EC number: 7.1.1.2)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0005148	MT-ND1	P03886	7.1.1.2	R-HSA-6799198 R-HSA-6799198 Reactome Name: Complex I biogenesis See in Reactome R-HSA-611105 R-HSA-611105 Reactome Name: Respiratory electron transport See in Reactome	R-HSA-1428517 R-HSA-1428517 Reactome Name: The citric acid (TCA) cycle and respiratory electron transport See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-163200 R-HSA-163200 Reactome Name: Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. See in Reactome	Metabolism	R-HSA-163217 ( R-HSA-611105 ) R-HSA-163217 Reaction Name: Complex I oxidises NADH to NAD+, reduces CoQ to QH2 See in Reactome R-HSA-6799179 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799179 Reaction Name: Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex See in Reactome R-HSA-6799191 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799191 Reaction Name: Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex See in Reactome R-HSA-6799196 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799196 Reaction Name: The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I See in Reactome R-HSA-6799197 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799197 Reaction Name: ND4, ND5 bind the 550kDa complex to form the 815kDa complex See in Reactome R-HSA-6799202 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799202 Reaction Name: The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex See in Reactome
MONDO:0010772	MT-ND4	P03905	7.1.1.2	R-HSA-6799198 R-HSA-6799198 Reactome Name: Complex I biogenesis See in Reactome R-HSA-611105 R-HSA-611105 Reactome Name: Respiratory electron transport See in Reactome	R-HSA-1428517 R-HSA-1428517 Reactome Name: The citric acid (TCA) cycle and respiratory electron transport See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-163200 R-HSA-163200 Reactome Name: Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. See in Reactome	Metabolism	R-HSA-163217 ( R-HSA-611105 ) R-HSA-163217 Reaction Name: Complex I oxidises NADH to NAD+, reduces CoQ to QH2 See in Reactome R-HSA-6799179 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799179 Reaction Name: Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex See in Reactome R-HSA-6799196 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799196 Reaction Name: The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I See in Reactome R-HSA-6799197 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799197 Reaction Name: ND4, ND5 bind the 550kDa complex to form the 815kDa complex See in Reactome
MONDO:0010772	MT-ND6	P03923	7.1.1.2	R-HSA-6799198 R-HSA-6799198 Reactome Name: Complex I biogenesis See in Reactome R-HSA-611105 R-HSA-611105 Reactome Name: Respiratory electron transport See in Reactome	R-HSA-1428517 R-HSA-1428517 Reactome Name: The citric acid (TCA) cycle and respiratory electron transport See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-163200 R-HSA-163200 Reactome Name: Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. See in Reactome	Metabolism	R-HSA-163217 ( R-HSA-611105 ) R-HSA-163217 Reaction Name: Complex I oxidises NADH to NAD+, reduces CoQ to QH2 See in Reactome R-HSA-6799179 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799179 Reaction Name: Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex See in Reactome R-HSA-6799196 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799196 Reaction Name: The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I See in Reactome R-HSA-6799197 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799197 Reaction Name: ND4, ND5 bind the 550kDa complex to form the 815kDa complex See in Reactome R-HSA-6799199 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799199 Reaction Name: COA1:MT-ND2, TMEM186:MT-ND3, MT-ND6, NDUFB6 bind the MCIA complex to form a 370kDa subcomplex See in Reactome R-HSA-6799202 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799202 Reaction Name: The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex See in Reactome
MONDO:0010783	MT-ND1	P03886	7.1.1.2	R-HSA-6799198 R-HSA-6799198 Reactome Name: Complex I biogenesis See in Reactome R-HSA-611105 R-HSA-611105 Reactome Name: Respiratory electron transport See in Reactome	R-HSA-1428517 R-HSA-1428517 Reactome Name: The citric acid (TCA) cycle and respiratory electron transport See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-163200 R-HSA-163200 Reactome Name: Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. See in Reactome	Metabolism	R-HSA-163217 ( R-HSA-611105 ) R-HSA-163217 Reaction Name: Complex I oxidises NADH to NAD+, reduces CoQ to QH2 See in Reactome R-HSA-6799179 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799179 Reaction Name: Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex See in Reactome R-HSA-6799191 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799191 Reaction Name: Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex See in Reactome R-HSA-6799196 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799196 Reaction Name: The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I See in Reactome R-HSA-6799197 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799197 Reaction Name: ND4, ND5 bind the 550kDa complex to form the 815kDa complex See in Reactome R-HSA-6799202 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799202 Reaction Name: The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex See in Reactome
MONDO:0010783	MT-ND2	P03891	7.1.1.2	R-HSA-6799198 R-HSA-6799198 Reactome Name: Complex I biogenesis See in Reactome R-HSA-611105 R-HSA-611105 Reactome Name: Respiratory electron transport See in Reactome	R-HSA-1428517 R-HSA-1428517 Reactome Name: The citric acid (TCA) cycle and respiratory electron transport See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-163200 R-HSA-163200 Reactome Name: Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. See in Reactome	Metabolism	R-HSA-163217 ( R-HSA-611105 ) R-HSA-163217 Reaction Name: Complex I oxidises NADH to NAD+, reduces CoQ to QH2 See in Reactome R-HSA-6799179 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799179 Reaction Name: Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex See in Reactome R-HSA-6799196 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799196 Reaction Name: The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I See in Reactome R-HSA-6799197 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799197 Reaction Name: ND4, ND5 bind the 550kDa complex to form the 815kDa complex See in Reactome R-HSA-6799199 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799199 Reaction Name: COA1:MT-ND2, TMEM186:MT-ND3, MT-ND6, NDUFB6 bind the MCIA complex to form a 370kDa subcomplex See in Reactome R-HSA-6799202 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799202 Reaction Name: The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex See in Reactome
MONDO:0010788	NDUFS2	O75306	7.1.1.2	R-HSA-6799198 R-HSA-6799198 Reactome Name: Complex I biogenesis See in Reactome R-HSA-611105 R-HSA-611105 Reactome Name: Respiratory electron transport See in Reactome	R-HSA-1428517 R-HSA-1428517 Reactome Name: The citric acid (TCA) cycle and respiratory electron transport See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-163200 R-HSA-163200 Reactome Name: Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. See in Reactome	Metabolism	R-HSA-163217 ( R-HSA-611105 ) R-HSA-163217 Reaction Name: Complex I oxidises NADH to NAD+, reduces CoQ to QH2 See in Reactome R-HSA-6788523 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6788523 Reaction Name: NUBPL transfers 4Fe-4S to Complex I subunits See in Reactome R-HSA-6799178 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799178 Reaction Name: Intermediate 1 binds HP subcomplex to form Intermediate 2 See in Reactome R-HSA-6799179 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799179 Reaction Name: Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex See in Reactome R-HSA-6799191 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799191 Reaction Name: Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex See in Reactome R-HSA-6799196 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799196 Reaction Name: The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I See in Reactome R-HSA-6799197 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799197 Reaction Name: ND4, ND5 bind the 550kDa complex to form the 815kDa complex See in Reactome R-HSA-6799202 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799202 Reaction Name: The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex See in Reactome R-HSA-6799203 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799203 Reaction Name: IP subcomplex binds NDUFAF3, NDUFAF4, TIMMDC1 to form Intermediate 1 See in Reactome R-HSA-6800868 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6800868 Reaction Name: NDUF subunits bind to form the IP subcomplex See in Reactome
MONDO:0010788	MT-ND1	P03886	7.1.1.2	R-HSA-6799198 R-HSA-6799198 Reactome Name: Complex I biogenesis See in Reactome R-HSA-611105 R-HSA-611105 Reactome Name: Respiratory electron transport See in Reactome	R-HSA-1428517 R-HSA-1428517 Reactome Name: The citric acid (TCA) cycle and respiratory electron transport See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-163200 R-HSA-163200 Reactome Name: Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. See in Reactome	Metabolism	R-HSA-163217 ( R-HSA-611105 ) R-HSA-163217 Reaction Name: Complex I oxidises NADH to NAD+, reduces CoQ to QH2 See in Reactome R-HSA-6799179 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799179 Reaction Name: Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex See in Reactome R-HSA-6799191 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799191 Reaction Name: Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex See in Reactome R-HSA-6799196 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799196 Reaction Name: The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I See in Reactome R-HSA-6799197 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799197 Reaction Name: ND4, ND5 bind the 550kDa complex to form the 815kDa complex See in Reactome R-HSA-6799202 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799202 Reaction Name: The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex See in Reactome
MONDO:0010788	MT-ND2	P03891	7.1.1.2	R-HSA-6799198 R-HSA-6799198 Reactome Name: Complex I biogenesis See in Reactome R-HSA-611105 R-HSA-611105 Reactome Name: Respiratory electron transport See in Reactome	R-HSA-1428517 R-HSA-1428517 Reactome Name: The citric acid (TCA) cycle and respiratory electron transport See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-163200 R-HSA-163200 Reactome Name: Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. See in Reactome	Metabolism	R-HSA-163217 ( R-HSA-611105 ) R-HSA-163217 Reaction Name: Complex I oxidises NADH to NAD+, reduces CoQ to QH2 See in Reactome R-HSA-6799179 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799179 Reaction Name: Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex See in Reactome R-HSA-6799196 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799196 Reaction Name: The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I See in Reactome R-HSA-6799197 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799197 Reaction Name: ND4, ND5 bind the 550kDa complex to form the 815kDa complex See in Reactome R-HSA-6799199 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799199 Reaction Name: COA1:MT-ND2, TMEM186:MT-ND3, MT-ND6, NDUFB6 bind the MCIA complex to form a 370kDa subcomplex See in Reactome R-HSA-6799202 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799202 Reaction Name: The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex See in Reactome
MONDO:0010788	MT-ND4L	P03901	7.1.1.2
MONDO:0010788	MT-ND5	P03915	7.1.1.2	R-HSA-6799198 R-HSA-6799198 Reactome Name: Complex I biogenesis See in Reactome R-HSA-611105 R-HSA-611105 Reactome Name: Respiratory electron transport See in Reactome	R-HSA-1428517 R-HSA-1428517 Reactome Name: The citric acid (TCA) cycle and respiratory electron transport See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-163200 R-HSA-163200 Reactome Name: Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. See in Reactome	Metabolism	R-HSA-163217 ( R-HSA-611105 ) R-HSA-163217 Reaction Name: Complex I oxidises NADH to NAD+, reduces CoQ to QH2 See in Reactome R-HSA-6799179 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799179 Reaction Name: Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex See in Reactome R-HSA-6799196 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799196 Reaction Name: The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I See in Reactome R-HSA-6799197 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799197 Reaction Name: ND4, ND5 bind the 550kDa complex to form the 815kDa complex See in Reactome
MONDO:0010789	MT-ND1	P03886	7.1.1.2	R-HSA-6799198 R-HSA-6799198 Reactome Name: Complex I biogenesis See in Reactome R-HSA-611105 R-HSA-611105 Reactome Name: Respiratory electron transport See in Reactome	R-HSA-1428517 R-HSA-1428517 Reactome Name: The citric acid (TCA) cycle and respiratory electron transport See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-163200 R-HSA-163200 Reactome Name: Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. See in Reactome	Metabolism	R-HSA-163217 ( R-HSA-611105 ) R-HSA-163217 Reaction Name: Complex I oxidises NADH to NAD+, reduces CoQ to QH2 See in Reactome R-HSA-6799179 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799179 Reaction Name: Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex See in Reactome R-HSA-6799191 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799191 Reaction Name: Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex See in Reactome R-HSA-6799196 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799196 Reaction Name: The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I See in Reactome R-HSA-6799197 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799197 Reaction Name: ND4, ND5 bind the 550kDa complex to form the 815kDa complex See in Reactome R-HSA-6799202 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799202 Reaction Name: The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex See in Reactome
MONDO:0010789	MT-ND4	P03905	7.1.1.2	R-HSA-6799198 R-HSA-6799198 Reactome Name: Complex I biogenesis See in Reactome R-HSA-611105 R-HSA-611105 Reactome Name: Respiratory electron transport See in Reactome	R-HSA-1428517 R-HSA-1428517 Reactome Name: The citric acid (TCA) cycle and respiratory electron transport See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-163200 R-HSA-163200 Reactome Name: Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. See in Reactome	Metabolism	R-HSA-163217 ( R-HSA-611105 ) R-HSA-163217 Reaction Name: Complex I oxidises NADH to NAD+, reduces CoQ to QH2 See in Reactome R-HSA-6799179 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799179 Reaction Name: Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex See in Reactome R-HSA-6799196 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799196 Reaction Name: The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I See in Reactome R-HSA-6799197 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799197 Reaction Name: ND4, ND5 bind the 550kDa complex to form the 815kDa complex See in Reactome
MONDO:0010789	MT-ND5	P03915	7.1.1.2	R-HSA-6799198 R-HSA-6799198 Reactome Name: Complex I biogenesis See in Reactome R-HSA-611105 R-HSA-611105 Reactome Name: Respiratory electron transport See in Reactome	R-HSA-1428517 R-HSA-1428517 Reactome Name: The citric acid (TCA) cycle and respiratory electron transport See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-163200 R-HSA-163200 Reactome Name: Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. See in Reactome	Metabolism	R-HSA-163217 ( R-HSA-611105 ) R-HSA-163217 Reaction Name: Complex I oxidises NADH to NAD+, reduces CoQ to QH2 See in Reactome R-HSA-6799179 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799179 Reaction Name: Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex See in Reactome R-HSA-6799196 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799196 Reaction Name: The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I See in Reactome R-HSA-6799197 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799197 Reaction Name: ND4, ND5 bind the 550kDa complex to form the 815kDa complex See in Reactome
MONDO:0010789	MT-ND6	P03923	7.1.1.2	R-HSA-6799198 R-HSA-6799198 Reactome Name: Complex I biogenesis See in Reactome R-HSA-611105 R-HSA-611105 Reactome Name: Respiratory electron transport See in Reactome	R-HSA-1428517 R-HSA-1428517 Reactome Name: The citric acid (TCA) cycle and respiratory electron transport See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-163200 R-HSA-163200 Reactome Name: Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. See in Reactome	Metabolism	R-HSA-163217 ( R-HSA-611105 ) R-HSA-163217 Reaction Name: Complex I oxidises NADH to NAD+, reduces CoQ to QH2 See in Reactome R-HSA-6799179 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799179 Reaction Name: Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex See in Reactome R-HSA-6799196 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799196 Reaction Name: The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I See in Reactome R-HSA-6799197 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799197 Reaction Name: ND4, ND5 bind the 550kDa complex to form the 815kDa complex See in Reactome R-HSA-6799199 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799199 Reaction Name: COA1:MT-ND2, TMEM186:MT-ND3, MT-ND6, NDUFB6 bind the MCIA complex to form a 370kDa subcomplex See in Reactome R-HSA-6799202 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799202 Reaction Name: The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex See in Reactome
MONDO:0010790	MT-ND5	P03915	7.1.1.2	R-HSA-6799198 R-HSA-6799198 Reactome Name: Complex I biogenesis See in Reactome R-HSA-611105 R-HSA-611105 Reactome Name: Respiratory electron transport See in Reactome	R-HSA-1428517 R-HSA-1428517 Reactome Name: The citric acid (TCA) cycle and respiratory electron transport See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-163200 R-HSA-163200 Reactome Name: Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. See in Reactome	Metabolism	R-HSA-163217 ( R-HSA-611105 ) R-HSA-163217 Reaction Name: Complex I oxidises NADH to NAD+, reduces CoQ to QH2 See in Reactome R-HSA-6799179 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799179 Reaction Name: Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex See in Reactome R-HSA-6799196 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799196 Reaction Name: The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I See in Reactome R-HSA-6799197 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799197 Reaction Name: ND4, ND5 bind the 550kDa complex to form the 815kDa complex See in Reactome
MONDO:0016814	MT-ND1	P03886	7.1.1.2	R-HSA-6799198 R-HSA-6799198 Reactome Name: Complex I biogenesis See in Reactome R-HSA-611105 R-HSA-611105 Reactome Name: Respiratory electron transport See in Reactome	R-HSA-1428517 R-HSA-1428517 Reactome Name: The citric acid (TCA) cycle and respiratory electron transport See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-163200 R-HSA-163200 Reactome Name: Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. See in Reactome	Metabolism	R-HSA-163217 ( R-HSA-611105 ) R-HSA-163217 Reaction Name: Complex I oxidises NADH to NAD+, reduces CoQ to QH2 See in Reactome R-HSA-6799179 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799179 Reaction Name: Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex See in Reactome R-HSA-6799191 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799191 Reaction Name: Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex See in Reactome R-HSA-6799196 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799196 Reaction Name: The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I See in Reactome R-HSA-6799197 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799197 Reaction Name: ND4, ND5 bind the 550kDa complex to form the 815kDa complex See in Reactome R-HSA-6799202 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799202 Reaction Name: The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex See in Reactome
MONDO:0016814	MT-ND2	P03891	7.1.1.2	R-HSA-6799198 R-HSA-6799198 Reactome Name: Complex I biogenesis See in Reactome R-HSA-611105 R-HSA-611105 Reactome Name: Respiratory electron transport See in Reactome	R-HSA-1428517 R-HSA-1428517 Reactome Name: The citric acid (TCA) cycle and respiratory electron transport See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-163200 R-HSA-163200 Reactome Name: Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. See in Reactome	Metabolism	R-HSA-163217 ( R-HSA-611105 ) R-HSA-163217 Reaction Name: Complex I oxidises NADH to NAD+, reduces CoQ to QH2 See in Reactome R-HSA-6799179 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799179 Reaction Name: Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex See in Reactome R-HSA-6799196 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799196 Reaction Name: The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I See in Reactome R-HSA-6799197 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799197 Reaction Name: ND4, ND5 bind the 550kDa complex to form the 815kDa complex See in Reactome R-HSA-6799199 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799199 Reaction Name: COA1:MT-ND2, TMEM186:MT-ND3, MT-ND6, NDUFB6 bind the MCIA complex to form a 370kDa subcomplex See in Reactome R-HSA-6799202 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799202 Reaction Name: The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex See in Reactome
MONDO:0016814	MT-ND3	P03897	7.1.1.2	R-HSA-6799198 R-HSA-6799198 Reactome Name: Complex I biogenesis See in Reactome R-HSA-611105 R-HSA-611105 Reactome Name: Respiratory electron transport See in Reactome	R-HSA-1428517 R-HSA-1428517 Reactome Name: The citric acid (TCA) cycle and respiratory electron transport See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-163200 R-HSA-163200 Reactome Name: Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. See in Reactome	Metabolism	R-HSA-163217 ( R-HSA-611105 ) R-HSA-163217 Reaction Name: Complex I oxidises NADH to NAD+, reduces CoQ to QH2 See in Reactome R-HSA-6799179 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799179 Reaction Name: Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex See in Reactome R-HSA-6799196 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799196 Reaction Name: The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I See in Reactome R-HSA-6799197 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799197 Reaction Name: ND4, ND5 bind the 550kDa complex to form the 815kDa complex See in Reactome R-HSA-6799199 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799199 Reaction Name: COA1:MT-ND2, TMEM186:MT-ND3, MT-ND6, NDUFB6 bind the MCIA complex to form a 370kDa subcomplex See in Reactome R-HSA-6799202 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799202 Reaction Name: The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex See in Reactome
MONDO:0016814	MT-ND4	P03905	7.1.1.2	R-HSA-6799198 R-HSA-6799198 Reactome Name: Complex I biogenesis See in Reactome R-HSA-611105 R-HSA-611105 Reactome Name: Respiratory electron transport See in Reactome	R-HSA-1428517 R-HSA-1428517 Reactome Name: The citric acid (TCA) cycle and respiratory electron transport See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-163200 R-HSA-163200 Reactome Name: Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. See in Reactome	Metabolism	R-HSA-163217 ( R-HSA-611105 ) R-HSA-163217 Reaction Name: Complex I oxidises NADH to NAD+, reduces CoQ to QH2 See in Reactome R-HSA-6799179 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799179 Reaction Name: Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex See in Reactome R-HSA-6799196 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799196 Reaction Name: The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I See in Reactome R-HSA-6799197 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799197 Reaction Name: ND4, ND5 bind the 550kDa complex to form the 815kDa complex See in Reactome
MONDO:0016814	MT-ND5	P03915	7.1.1.2	R-HSA-6799198 R-HSA-6799198 Reactome Name: Complex I biogenesis See in Reactome R-HSA-611105 R-HSA-611105 Reactome Name: Respiratory electron transport See in Reactome	R-HSA-1428517 R-HSA-1428517 Reactome Name: The citric acid (TCA) cycle and respiratory electron transport See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-163200 R-HSA-163200 Reactome Name: Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. See in Reactome	Metabolism	R-HSA-163217 ( R-HSA-611105 ) R-HSA-163217 Reaction Name: Complex I oxidises NADH to NAD+, reduces CoQ to QH2 See in Reactome R-HSA-6799179 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799179 Reaction Name: Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex See in Reactome R-HSA-6799196 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799196 Reaction Name: The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I See in Reactome R-HSA-6799197 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799197 Reaction Name: ND4, ND5 bind the 550kDa complex to form the 815kDa complex See in Reactome
MONDO:0016814	MT-ND6	P03923	7.1.1.2	R-HSA-6799198 R-HSA-6799198 Reactome Name: Complex I biogenesis See in Reactome R-HSA-611105 R-HSA-611105 Reactome Name: Respiratory electron transport See in Reactome	R-HSA-1428517 R-HSA-1428517 Reactome Name: The citric acid (TCA) cycle and respiratory electron transport See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-163200 R-HSA-163200 Reactome Name: Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. See in Reactome	Metabolism	R-HSA-163217 ( R-HSA-611105 ) R-HSA-163217 Reaction Name: Complex I oxidises NADH to NAD+, reduces CoQ to QH2 See in Reactome R-HSA-6799179 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799179 Reaction Name: Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex See in Reactome R-HSA-6799196 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799196 Reaction Name: The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I See in Reactome R-HSA-6799197 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799197 Reaction Name: ND4, ND5 bind the 550kDa complex to form the 815kDa complex See in Reactome R-HSA-6799199 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799199 Reaction Name: COA1:MT-ND2, TMEM186:MT-ND3, MT-ND6, NDUFB6 bind the MCIA complex to form a 370kDa subcomplex See in Reactome R-HSA-6799202 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799202 Reaction Name: The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex See in Reactome
MONDO:0016815	NDUFS8	O00217	7.1.1.2	R-HSA-6799198 R-HSA-6799198 Reactome Name: Complex I biogenesis See in Reactome R-HSA-611105 R-HSA-611105 Reactome Name: Respiratory electron transport See in Reactome	R-HSA-1428517 R-HSA-1428517 Reactome Name: The citric acid (TCA) cycle and respiratory electron transport See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-163200 R-HSA-163200 Reactome Name: Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. See in Reactome	Metabolism	R-HSA-163217 ( R-HSA-611105 ) R-HSA-163217 Reaction Name: Complex I oxidises NADH to NAD+, reduces CoQ to QH2 See in Reactome R-HSA-6788523 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6788523 Reaction Name: NUBPL transfers 4Fe-4S to Complex I subunits See in Reactome R-HSA-6799178 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799178 Reaction Name: Intermediate 1 binds HP subcomplex to form Intermediate 2 See in Reactome R-HSA-6799179 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799179 Reaction Name: Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex See in Reactome R-HSA-6799191 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799191 Reaction Name: Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex See in Reactome R-HSA-6799196 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799196 Reaction Name: The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I See in Reactome R-HSA-6799197 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799197 Reaction Name: ND4, ND5 bind the 550kDa complex to form the 815kDa complex See in Reactome R-HSA-6799202 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799202 Reaction Name: The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex See in Reactome R-HSA-6799203 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799203 Reaction Name: IP subcomplex binds NDUFAF3, NDUFAF4, TIMMDC1 to form Intermediate 1 See in Reactome R-HSA-6800868 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6800868 Reaction Name: NDUF subunits bind to form the IP subcomplex See in Reactome
MONDO:0016815	NDUFS7	O75251	7.1.1.2	R-HSA-6799198 R-HSA-6799198 Reactome Name: Complex I biogenesis See in Reactome R-HSA-611105 R-HSA-611105 Reactome Name: Respiratory electron transport See in Reactome	R-HSA-1428517 R-HSA-1428517 Reactome Name: The citric acid (TCA) cycle and respiratory electron transport See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-163200 R-HSA-163200 Reactome Name: Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. See in Reactome	Metabolism	R-HSA-163217 ( R-HSA-611105 ) R-HSA-163217 Reaction Name: Complex I oxidises NADH to NAD+, reduces CoQ to QH2 See in Reactome R-HSA-6788523 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6788523 Reaction Name: NUBPL transfers 4Fe-4S to Complex I subunits See in Reactome R-HSA-6799178 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799178 Reaction Name: Intermediate 1 binds HP subcomplex to form Intermediate 2 See in Reactome R-HSA-6799179 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799179 Reaction Name: Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex See in Reactome R-HSA-6799191 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799191 Reaction Name: Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex See in Reactome R-HSA-6799196 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799196 Reaction Name: The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I See in Reactome R-HSA-6799197 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799197 Reaction Name: ND4, ND5 bind the 550kDa complex to form the 815kDa complex See in Reactome R-HSA-6799202 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799202 Reaction Name: The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex See in Reactome R-HSA-6799203 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799203 Reaction Name: IP subcomplex binds NDUFAF3, NDUFAF4, TIMMDC1 to form Intermediate 1 See in Reactome R-HSA-6800868 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6800868 Reaction Name: NDUF subunits bind to form the IP subcomplex See in Reactome
MONDO:0016815	NDUFS2	O75306	7.1.1.2	R-HSA-6799198 R-HSA-6799198 Reactome Name: Complex I biogenesis See in Reactome R-HSA-611105 R-HSA-611105 Reactome Name: Respiratory electron transport See in Reactome	R-HSA-1428517 R-HSA-1428517 Reactome Name: The citric acid (TCA) cycle and respiratory electron transport See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-163200 R-HSA-163200 Reactome Name: Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. See in Reactome	Metabolism	R-HSA-163217 ( R-HSA-611105 ) R-HSA-163217 Reaction Name: Complex I oxidises NADH to NAD+, reduces CoQ to QH2 See in Reactome R-HSA-6788523 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6788523 Reaction Name: NUBPL transfers 4Fe-4S to Complex I subunits See in Reactome R-HSA-6799178 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799178 Reaction Name: Intermediate 1 binds HP subcomplex to form Intermediate 2 See in Reactome R-HSA-6799179 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799179 Reaction Name: Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex See in Reactome R-HSA-6799191 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799191 Reaction Name: Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex See in Reactome R-HSA-6799196 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799196 Reaction Name: The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I See in Reactome R-HSA-6799197 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799197 Reaction Name: ND4, ND5 bind the 550kDa complex to form the 815kDa complex See in Reactome R-HSA-6799202 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799202 Reaction Name: The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex See in Reactome R-HSA-6799203 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799203 Reaction Name: IP subcomplex binds NDUFAF3, NDUFAF4, TIMMDC1 to form Intermediate 1 See in Reactome R-HSA-6800868 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6800868 Reaction Name: NDUF subunits bind to form the IP subcomplex See in Reactome
MONDO:0016815	NDUFS3	O75489	7.1.1.2	R-HSA-6799198 R-HSA-6799198 Reactome Name: Complex I biogenesis See in Reactome R-HSA-611105 R-HSA-611105 Reactome Name: Respiratory electron transport See in Reactome R-HSA-9013408 R-HSA-9013408 Reactome Name: RHOG GTPase cycle See in Reactome	R-HSA-163200 R-HSA-163200 Reactome Name: Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. See in Reactome R-HSA-9012999 R-HSA-9012999 Reactome Name: RHO GTPase cycle See in Reactome R-HSA-1428517 R-HSA-1428517 Reactome Name: The citric acid (TCA) cycle and respiratory electron transport See in Reactome R-HSA-194315 R-HSA-194315 Reactome Name: Signaling by Rho GTPases See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-9716542 R-HSA-9716542 Reactome Name: Signaling by Rho GTPases, Miro GTPases and RHOBTB3 See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Metabolism Signal Transduction	R-HSA-163217 ( R-HSA-611105 ) R-HSA-163217 Reaction Name: Complex I oxidises NADH to NAD+, reduces CoQ to QH2 See in Reactome R-HSA-6799178 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799178 Reaction Name: Intermediate 1 binds HP subcomplex to form Intermediate 2 See in Reactome R-HSA-6799179 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799179 Reaction Name: Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex See in Reactome R-HSA-6799191 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799191 Reaction Name: Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex See in Reactome R-HSA-6799196 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799196 Reaction Name: The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I See in Reactome R-HSA-6799197 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799197 Reaction Name: ND4, ND5 bind the 550kDa complex to form the 815kDa complex See in Reactome R-HSA-6799202 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799202 Reaction Name: The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex See in Reactome R-HSA-6799203 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799203 Reaction Name: IP subcomplex binds NDUFAF3, NDUFAF4, TIMMDC1 to form Intermediate 1 See in Reactome R-HSA-6800868 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6800868 Reaction Name: NDUF subunits bind to form the IP subcomplex See in Reactome R-HSA-9014449 ( R-HSA-9013408 ) R-HSA-9014449 Reaction Name: RHOG binds effectors at the plasma membrane See in Reactome
MONDO:0016815	NDUFV2	P19404	7.1.1.2	R-HSA-6799198 R-HSA-6799198 Reactome Name: Complex I biogenesis See in Reactome R-HSA-611105 R-HSA-611105 Reactome Name: Respiratory electron transport See in Reactome	R-HSA-1428517 R-HSA-1428517 Reactome Name: The citric acid (TCA) cycle and respiratory electron transport See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-163200 R-HSA-163200 Reactome Name: Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. See in Reactome	Metabolism	R-HSA-163217 ( R-HSA-611105 ) R-HSA-163217 Reaction Name: Complex I oxidises NADH to NAD+, reduces CoQ to QH2 See in Reactome R-HSA-6788556 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6788556 Reaction Name: NUBPL transfers 4Fe-4S to NDUFV1, V2 See in Reactome R-HSA-6799179 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799179 Reaction Name: Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex See in Reactome R-HSA-6799196 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799196 Reaction Name: The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I See in Reactome R-HSA-6800870 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6800870 Reaction Name: NDUF subunits bind to form the FP subcomplex See in Reactome
MONDO:0016815	NDUFS1	P28331	7.1.1.2	R-HSA-6799198 R-HSA-6799198 Reactome Name: Complex I biogenesis See in Reactome R-HSA-611105 R-HSA-611105 Reactome Name: Respiratory electron transport See in Reactome	R-HSA-1428517 R-HSA-1428517 Reactome Name: The citric acid (TCA) cycle and respiratory electron transport See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-163200 R-HSA-163200 Reactome Name: Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. See in Reactome	Metabolism	R-HSA-163217 ( R-HSA-611105 ) R-HSA-163217 Reaction Name: Complex I oxidises NADH to NAD+, reduces CoQ to QH2 See in Reactome R-HSA-6788523 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6788523 Reaction Name: NUBPL transfers 4Fe-4S to Complex I subunits See in Reactome R-HSA-6799179 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799179 Reaction Name: Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex See in Reactome R-HSA-6799196 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799196 Reaction Name: The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I See in Reactome R-HSA-6800870 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6800870 Reaction Name: NDUF subunits bind to form the FP subcomplex See in Reactome
MONDO:0016815	NDUFV1	P49821	7.1.1.2	R-HSA-6799198 R-HSA-6799198 Reactome Name: Complex I biogenesis See in Reactome R-HSA-611105 R-HSA-611105 Reactome Name: Respiratory electron transport See in Reactome	R-HSA-1428517 R-HSA-1428517 Reactome Name: The citric acid (TCA) cycle and respiratory electron transport See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-163200 R-HSA-163200 Reactome Name: Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. See in Reactome	Metabolism	R-HSA-163217 ( R-HSA-611105 ) R-HSA-163217 Reaction Name: Complex I oxidises NADH to NAD+, reduces CoQ to QH2 See in Reactome R-HSA-6788556 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6788556 Reaction Name: NUBPL transfers 4Fe-4S to NDUFV1, V2 See in Reactome R-HSA-6799179 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799179 Reaction Name: Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex See in Reactome R-HSA-6799196 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799196 Reaction Name: The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I See in Reactome R-HSA-6800870 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6800870 Reaction Name: NDUF subunits bind to form the FP subcomplex See in Reactome
MONDO:0019083	NDUFS2	O75306	7.1.1.2	R-HSA-6799198 R-HSA-6799198 Reactome Name: Complex I biogenesis See in Reactome R-HSA-611105 R-HSA-611105 Reactome Name: Respiratory electron transport See in Reactome	R-HSA-1428517 R-HSA-1428517 Reactome Name: The citric acid (TCA) cycle and respiratory electron transport See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-163200 R-HSA-163200 Reactome Name: Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. See in Reactome	Metabolism	R-HSA-163217 ( R-HSA-611105 ) R-HSA-163217 Reaction Name: Complex I oxidises NADH to NAD+, reduces CoQ to QH2 See in Reactome R-HSA-6788523 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6788523 Reaction Name: NUBPL transfers 4Fe-4S to Complex I subunits See in Reactome R-HSA-6799178 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799178 Reaction Name: Intermediate 1 binds HP subcomplex to form Intermediate 2 See in Reactome R-HSA-6799179 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799179 Reaction Name: Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex See in Reactome R-HSA-6799191 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799191 Reaction Name: Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex See in Reactome R-HSA-6799196 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799196 Reaction Name: The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I See in Reactome R-HSA-6799197 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799197 Reaction Name: ND4, ND5 bind the 550kDa complex to form the 815kDa complex See in Reactome R-HSA-6799202 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799202 Reaction Name: The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex See in Reactome R-HSA-6799203 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799203 Reaction Name: IP subcomplex binds NDUFAF3, NDUFAF4, TIMMDC1 to form Intermediate 1 See in Reactome R-HSA-6800868 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6800868 Reaction Name: NDUF subunits bind to form the IP subcomplex See in Reactome
MONDO:0020478	MT-ND3	P03897	7.1.1.2	R-HSA-6799198 R-HSA-6799198 Reactome Name: Complex I biogenesis See in Reactome R-HSA-611105 R-HSA-611105 Reactome Name: Respiratory electron transport See in Reactome	R-HSA-1428517 R-HSA-1428517 Reactome Name: The citric acid (TCA) cycle and respiratory electron transport See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-163200 R-HSA-163200 Reactome Name: Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. See in Reactome	Metabolism	R-HSA-163217 ( R-HSA-611105 ) R-HSA-163217 Reaction Name: Complex I oxidises NADH to NAD+, reduces CoQ to QH2 See in Reactome R-HSA-6799179 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799179 Reaction Name: Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex See in Reactome R-HSA-6799196 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799196 Reaction Name: The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I See in Reactome R-HSA-6799197 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799197 Reaction Name: ND4, ND5 bind the 550kDa complex to form the 815kDa complex See in Reactome R-HSA-6799199 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799199 Reaction Name: COA1:MT-ND2, TMEM186:MT-ND3, MT-ND6, NDUFB6 bind the MCIA complex to form a 370kDa subcomplex See in Reactome R-HSA-6799202 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799202 Reaction Name: The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex See in Reactome
MONDO:0027068	MT-ND3	P03897	7.1.1.2	R-HSA-6799198 R-HSA-6799198 Reactome Name: Complex I biogenesis See in Reactome R-HSA-611105 R-HSA-611105 Reactome Name: Respiratory electron transport See in Reactome	R-HSA-1428517 R-HSA-1428517 Reactome Name: The citric acid (TCA) cycle and respiratory electron transport See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-163200 R-HSA-163200 Reactome Name: Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. See in Reactome	Metabolism	R-HSA-163217 ( R-HSA-611105 ) R-HSA-163217 Reaction Name: Complex I oxidises NADH to NAD+, reduces CoQ to QH2 See in Reactome R-HSA-6799179 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799179 Reaction Name: Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex See in Reactome R-HSA-6799196 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799196 Reaction Name: The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I See in Reactome R-HSA-6799197 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799197 Reaction Name: ND4, ND5 bind the 550kDa complex to form the 815kDa complex See in Reactome R-HSA-6799199 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799199 Reaction Name: COA1:MT-ND2, TMEM186:MT-ND3, MT-ND6, NDUFB6 bind the MCIA complex to form a 370kDa subcomplex See in Reactome R-HSA-6799202 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799202 Reaction Name: The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex See in Reactome
MONDO:0032606	NDUFS8	O00217	7.1.1.2	R-HSA-6799198 R-HSA-6799198 Reactome Name: Complex I biogenesis See in Reactome R-HSA-611105 R-HSA-611105 Reactome Name: Respiratory electron transport See in Reactome	R-HSA-1428517 R-HSA-1428517 Reactome Name: The citric acid (TCA) cycle and respiratory electron transport See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-163200 R-HSA-163200 Reactome Name: Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. See in Reactome	Metabolism	R-HSA-163217 ( R-HSA-611105 ) R-HSA-163217 Reaction Name: Complex I oxidises NADH to NAD+, reduces CoQ to QH2 See in Reactome R-HSA-6788523 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6788523 Reaction Name: NUBPL transfers 4Fe-4S to Complex I subunits See in Reactome R-HSA-6799178 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799178 Reaction Name: Intermediate 1 binds HP subcomplex to form Intermediate 2 See in Reactome R-HSA-6799179 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799179 Reaction Name: Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex See in Reactome R-HSA-6799191 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799191 Reaction Name: Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex See in Reactome R-HSA-6799196 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799196 Reaction Name: The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I See in Reactome R-HSA-6799197 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799197 Reaction Name: ND4, ND5 bind the 550kDa complex to form the 815kDa complex See in Reactome R-HSA-6799202 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799202 Reaction Name: The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex See in Reactome R-HSA-6799203 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799203 Reaction Name: IP subcomplex binds NDUFAF3, NDUFAF4, TIMMDC1 to form Intermediate 1 See in Reactome R-HSA-6800868 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6800868 Reaction Name: NDUF subunits bind to form the IP subcomplex See in Reactome
MONDO:0032608	NDUFS7	O75251	7.1.1.2	R-HSA-6799198 R-HSA-6799198 Reactome Name: Complex I biogenesis See in Reactome R-HSA-611105 R-HSA-611105 Reactome Name: Respiratory electron transport See in Reactome	R-HSA-1428517 R-HSA-1428517 Reactome Name: The citric acid (TCA) cycle and respiratory electron transport See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-163200 R-HSA-163200 Reactome Name: Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. See in Reactome	Metabolism	R-HSA-163217 ( R-HSA-611105 ) R-HSA-163217 Reaction Name: Complex I oxidises NADH to NAD+, reduces CoQ to QH2 See in Reactome R-HSA-6788523 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6788523 Reaction Name: NUBPL transfers 4Fe-4S to Complex I subunits See in Reactome R-HSA-6799178 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799178 Reaction Name: Intermediate 1 binds HP subcomplex to form Intermediate 2 See in Reactome R-HSA-6799179 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799179 Reaction Name: Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex See in Reactome R-HSA-6799191 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799191 Reaction Name: Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex See in Reactome R-HSA-6799196 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799196 Reaction Name: The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I See in Reactome R-HSA-6799197 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799197 Reaction Name: ND4, ND5 bind the 550kDa complex to form the 815kDa complex See in Reactome R-HSA-6799202 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799202 Reaction Name: The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex See in Reactome R-HSA-6799203 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799203 Reaction Name: IP subcomplex binds NDUFAF3, NDUFAF4, TIMMDC1 to form Intermediate 1 See in Reactome R-HSA-6800868 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6800868 Reaction Name: NDUF subunits bind to form the IP subcomplex See in Reactome
MONDO:0032609	NDUFV1	P49821	7.1.1.2	R-HSA-6799198 R-HSA-6799198 Reactome Name: Complex I biogenesis See in Reactome R-HSA-611105 R-HSA-611105 Reactome Name: Respiratory electron transport See in Reactome	R-HSA-1428517 R-HSA-1428517 Reactome Name: The citric acid (TCA) cycle and respiratory electron transport See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-163200 R-HSA-163200 Reactome Name: Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. See in Reactome	Metabolism	R-HSA-163217 ( R-HSA-611105 ) R-HSA-163217 Reaction Name: Complex I oxidises NADH to NAD+, reduces CoQ to QH2 See in Reactome R-HSA-6788556 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6788556 Reaction Name: NUBPL transfers 4Fe-4S to NDUFV1, V2 See in Reactome R-HSA-6799179 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799179 Reaction Name: Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex See in Reactome R-HSA-6799196 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799196 Reaction Name: The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I See in Reactome R-HSA-6800870 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6800870 Reaction Name: NDUF subunits bind to form the FP subcomplex See in Reactome
MONDO:0032610	NDUFS1	P28331	7.1.1.2	R-HSA-6799198 R-HSA-6799198 Reactome Name: Complex I biogenesis See in Reactome R-HSA-611105 R-HSA-611105 Reactome Name: Respiratory electron transport See in Reactome	R-HSA-1428517 R-HSA-1428517 Reactome Name: The citric acid (TCA) cycle and respiratory electron transport See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-163200 R-HSA-163200 Reactome Name: Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. See in Reactome	Metabolism	R-HSA-163217 ( R-HSA-611105 ) R-HSA-163217 Reaction Name: Complex I oxidises NADH to NAD+, reduces CoQ to QH2 See in Reactome R-HSA-6788523 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6788523 Reaction Name: NUBPL transfers 4Fe-4S to Complex I subunits See in Reactome R-HSA-6799179 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799179 Reaction Name: Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex See in Reactome R-HSA-6799196 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799196 Reaction Name: The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I See in Reactome R-HSA-6800870 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6800870 Reaction Name: NDUF subunits bind to form the FP subcomplex See in Reactome
MONDO:0032611	NDUFS2	O75306	7.1.1.2	R-HSA-6799198 R-HSA-6799198 Reactome Name: Complex I biogenesis See in Reactome R-HSA-611105 R-HSA-611105 Reactome Name: Respiratory electron transport See in Reactome	R-HSA-1428517 R-HSA-1428517 Reactome Name: The citric acid (TCA) cycle and respiratory electron transport See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-163200 R-HSA-163200 Reactome Name: Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. See in Reactome	Metabolism	R-HSA-163217 ( R-HSA-611105 ) R-HSA-163217 Reaction Name: Complex I oxidises NADH to NAD+, reduces CoQ to QH2 See in Reactome R-HSA-6788523 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6788523 Reaction Name: NUBPL transfers 4Fe-4S to Complex I subunits See in Reactome R-HSA-6799178 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799178 Reaction Name: Intermediate 1 binds HP subcomplex to form Intermediate 2 See in Reactome R-HSA-6799179 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799179 Reaction Name: Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex See in Reactome R-HSA-6799191 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799191 Reaction Name: Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex See in Reactome R-HSA-6799196 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799196 Reaction Name: The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I See in Reactome R-HSA-6799197 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799197 Reaction Name: ND4, ND5 bind the 550kDa complex to form the 815kDa complex See in Reactome R-HSA-6799202 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799202 Reaction Name: The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex See in Reactome R-HSA-6799203 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799203 Reaction Name: IP subcomplex binds NDUFAF3, NDUFAF4, TIMMDC1 to form Intermediate 1 See in Reactome R-HSA-6800868 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6800868 Reaction Name: NDUF subunits bind to form the IP subcomplex See in Reactome
MONDO:0032612	NDUFV2	P19404	7.1.1.2	R-HSA-6799198 R-HSA-6799198 Reactome Name: Complex I biogenesis See in Reactome R-HSA-611105 R-HSA-611105 Reactome Name: Respiratory electron transport See in Reactome	R-HSA-1428517 R-HSA-1428517 Reactome Name: The citric acid (TCA) cycle and respiratory electron transport See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-163200 R-HSA-163200 Reactome Name: Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. See in Reactome	Metabolism	R-HSA-163217 ( R-HSA-611105 ) R-HSA-163217 Reaction Name: Complex I oxidises NADH to NAD+, reduces CoQ to QH2 See in Reactome R-HSA-6788556 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6788556 Reaction Name: NUBPL transfers 4Fe-4S to NDUFV1, V2 See in Reactome R-HSA-6799179 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799179 Reaction Name: Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex See in Reactome R-HSA-6799196 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799196 Reaction Name: The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I See in Reactome R-HSA-6800870 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6800870 Reaction Name: NDUF subunits bind to form the FP subcomplex See in Reactome
MONDO:0032613	NDUFS3	O75489	7.1.1.2	R-HSA-6799198 R-HSA-6799198 Reactome Name: Complex I biogenesis See in Reactome R-HSA-611105 R-HSA-611105 Reactome Name: Respiratory electron transport See in Reactome R-HSA-9013408 R-HSA-9013408 Reactome Name: RHOG GTPase cycle See in Reactome	R-HSA-163200 R-HSA-163200 Reactome Name: Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. See in Reactome R-HSA-9012999 R-HSA-9012999 Reactome Name: RHO GTPase cycle See in Reactome R-HSA-1428517 R-HSA-1428517 Reactome Name: The citric acid (TCA) cycle and respiratory electron transport See in Reactome R-HSA-194315 R-HSA-194315 Reactome Name: Signaling by Rho GTPases See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-9716542 R-HSA-9716542 Reactome Name: Signaling by Rho GTPases, Miro GTPases and RHOBTB3 See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Metabolism Signal Transduction	R-HSA-163217 ( R-HSA-611105 ) R-HSA-163217 Reaction Name: Complex I oxidises NADH to NAD+, reduces CoQ to QH2 See in Reactome R-HSA-6799178 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799178 Reaction Name: Intermediate 1 binds HP subcomplex to form Intermediate 2 See in Reactome R-HSA-6799179 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799179 Reaction Name: Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex See in Reactome R-HSA-6799191 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799191 Reaction Name: Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex See in Reactome R-HSA-6799196 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799196 Reaction Name: The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I See in Reactome R-HSA-6799197 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799197 Reaction Name: ND4, ND5 bind the 550kDa complex to form the 815kDa complex See in Reactome R-HSA-6799202 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799202 Reaction Name: The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex See in Reactome R-HSA-6799203 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799203 Reaction Name: IP subcomplex binds NDUFAF3, NDUFAF4, TIMMDC1 to form Intermediate 1 See in Reactome R-HSA-6800868 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6800868 Reaction Name: NDUF subunits bind to form the IP subcomplex See in Reactome R-HSA-9014449 ( R-HSA-9013408 ) R-HSA-9014449 Reaction Name: RHOG binds effectors at the plasma membrane See in Reactome
MONDO:0100133	MT-ND1	P03886	7.1.1.2	R-HSA-6799198 R-HSA-6799198 Reactome Name: Complex I biogenesis See in Reactome R-HSA-611105 R-HSA-611105 Reactome Name: Respiratory electron transport See in Reactome	R-HSA-1428517 R-HSA-1428517 Reactome Name: The citric acid (TCA) cycle and respiratory electron transport See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-163200 R-HSA-163200 Reactome Name: Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. See in Reactome	Metabolism	R-HSA-163217 ( R-HSA-611105 ) R-HSA-163217 Reaction Name: Complex I oxidises NADH to NAD+, reduces CoQ to QH2 See in Reactome R-HSA-6799179 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799179 Reaction Name: Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex See in Reactome R-HSA-6799191 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799191 Reaction Name: Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex See in Reactome R-HSA-6799196 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799196 Reaction Name: The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I See in Reactome R-HSA-6799197 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799197 Reaction Name: ND4, ND5 bind the 550kDa complex to form the 815kDa complex See in Reactome R-HSA-6799202 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799202 Reaction Name: The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex See in Reactome
MONDO:0100133	MT-ND2	P03891	7.1.1.2	R-HSA-6799198 R-HSA-6799198 Reactome Name: Complex I biogenesis See in Reactome R-HSA-611105 R-HSA-611105 Reactome Name: Respiratory electron transport See in Reactome	R-HSA-1428517 R-HSA-1428517 Reactome Name: The citric acid (TCA) cycle and respiratory electron transport See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-163200 R-HSA-163200 Reactome Name: Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. See in Reactome	Metabolism	R-HSA-163217 ( R-HSA-611105 ) R-HSA-163217 Reaction Name: Complex I oxidises NADH to NAD+, reduces CoQ to QH2 See in Reactome R-HSA-6799179 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799179 Reaction Name: Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex See in Reactome R-HSA-6799196 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799196 Reaction Name: The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I See in Reactome R-HSA-6799197 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799197 Reaction Name: ND4, ND5 bind the 550kDa complex to form the 815kDa complex See in Reactome R-HSA-6799199 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799199 Reaction Name: COA1:MT-ND2, TMEM186:MT-ND3, MT-ND6, NDUFB6 bind the MCIA complex to form a 370kDa subcomplex See in Reactome R-HSA-6799202 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799202 Reaction Name: The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex See in Reactome
MONDO:0100224	NDUFS1	P28331	7.1.1.2	R-HSA-6799198 R-HSA-6799198 Reactome Name: Complex I biogenesis See in Reactome R-HSA-611105 R-HSA-611105 Reactome Name: Respiratory electron transport See in Reactome	R-HSA-1428517 R-HSA-1428517 Reactome Name: The citric acid (TCA) cycle and respiratory electron transport See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-163200 R-HSA-163200 Reactome Name: Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. See in Reactome	Metabolism	R-HSA-163217 ( R-HSA-611105 ) R-HSA-163217 Reaction Name: Complex I oxidises NADH to NAD+, reduces CoQ to QH2 See in Reactome R-HSA-6788523 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6788523 Reaction Name: NUBPL transfers 4Fe-4S to Complex I subunits See in Reactome R-HSA-6799179 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799179 Reaction Name: Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex See in Reactome R-HSA-6799196 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799196 Reaction Name: The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I See in Reactome R-HSA-6800870 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6800870 Reaction Name: NDUF subunits bind to form the FP subcomplex See in Reactome
MONDO:0100224	NDUFV1	P49821	7.1.1.2	R-HSA-6799198 R-HSA-6799198 Reactome Name: Complex I biogenesis See in Reactome R-HSA-611105 R-HSA-611105 Reactome Name: Respiratory electron transport See in Reactome	R-HSA-1428517 R-HSA-1428517 Reactome Name: The citric acid (TCA) cycle and respiratory electron transport See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-163200 R-HSA-163200 Reactome Name: Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. See in Reactome	Metabolism	R-HSA-163217 ( R-HSA-611105 ) R-HSA-163217 Reaction Name: Complex I oxidises NADH to NAD+, reduces CoQ to QH2 See in Reactome R-HSA-6788556 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6788556 Reaction Name: NUBPL transfers 4Fe-4S to NDUFV1, V2 See in Reactome R-HSA-6799179 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799179 Reaction Name: Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex See in Reactome R-HSA-6799196 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799196 Reaction Name: The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I See in Reactome R-HSA-6800870 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6800870 Reaction Name: NDUF subunits bind to form the FP subcomplex See in Reactome

Number of enzymes:	14
Number of disease:	20
Number of reactomes:	3
Number of reactions:	14

Search summary (EC number: 7.1.1.2)

Search results (EC number: 7.1.1.2)

MONDO:0005148

R-HSA-6799198

R-HSA-611105

R-HSA-1428517

R-HSA-1430728

R-HSA-163200

R-HSA-163217

R-HSA-6799179

R-HSA-6799191

R-HSA-6799196

R-HSA-6799197

R-HSA-6799202

MONDO:0010772

R-HSA-6799198

R-HSA-611105

R-HSA-1428517

R-HSA-1430728

R-HSA-163200

R-HSA-163217

R-HSA-6799179

R-HSA-6799196

R-HSA-6799197

MONDO:0010772

R-HSA-6799198

R-HSA-611105

R-HSA-1428517

R-HSA-1430728

R-HSA-163200

R-HSA-163217

R-HSA-6799179

R-HSA-6799196

R-HSA-6799197

R-HSA-6799199

R-HSA-6799202

MONDO:0010783

R-HSA-6799198

R-HSA-611105

R-HSA-1428517

R-HSA-1430728

R-HSA-163200

R-HSA-163217

R-HSA-6799179

R-HSA-6799191

R-HSA-6799196

R-HSA-6799197

R-HSA-6799202

MONDO:0010783

R-HSA-6799198

R-HSA-611105

R-HSA-1428517

R-HSA-1430728

R-HSA-163200

R-HSA-163217

R-HSA-6799179

R-HSA-6799196

R-HSA-6799197

R-HSA-6799199

R-HSA-6799202

MONDO:0010788

R-HSA-6799198

R-HSA-611105

R-HSA-1428517

R-HSA-1430728

R-HSA-163200

R-HSA-163217

R-HSA-6788523

R-HSA-6799178

R-HSA-6799179

R-HSA-6799191

R-HSA-6799196

R-HSA-6799197

R-HSA-6799202

R-HSA-6799203

R-HSA-6800868

MONDO:0010788

R-HSA-6799198

R-HSA-611105

R-HSA-1428517