DAR - Bologna Biocomputing Group

Search summary (EC number: 6.2.1.45)

Number of enzymes:	1
Number of disease:	2
Number of reactomes:	2
Number of reactions:	10

Search results (EC number: 6.2.1.45)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0010532	UBA1	P22314	6.2.1.45	R-HSA-8866652 R-HSA-8866652 Reactome Name: Synthesis of active ubiquitin: roles of E1 and E2 enzymes See in Reactome R-HSA-983168 R-HSA-983168 Reactome Name: Antigen processing: Ubiquitination & Proteasome degradation See in Reactome	R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-983169 R-HSA-983169 Reactome Name: Class I MHC mediated antigen processing & presentation See in Reactome R-HSA-8852135 R-HSA-8852135 Reactome Name: Protein ubiquitination See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome R-HSA-1280218 R-HSA-1280218 Reactome Name: Adaptive Immune System See in Reactome	Immune System Metabolism of proteins	R-HSA-8852128 ( R-HSA-8866652 ) R-HSA-8852128 Reaction Name: UBA1 adenylates ubiquitin in the nucleoplasm See in Reactome R-HSA-8852129 ( R-HSA-8866652 ) R-HSA-8852129 Reaction Name: UBA1 conjugates ubiquitin to cytosolic E2 enzymes See in Reactome R-HSA-8852130 ( R-HSA-8866652 ) R-HSA-8852130 Reaction Name: UBA1 conjugates ubiquitin to nuclear E2 enzymes See in Reactome R-HSA-8852131 ( R-HSA-8866652 ) R-HSA-8852131 Reaction Name: Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus See in Reactome R-HSA-8852132 ( R-HSA-8866652 ) R-HSA-8852132 Reaction Name: Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol See in Reactome R-HSA-8852133 ( R-HSA-8866652 ) R-HSA-8852133 Reaction Name: UBA1 conjugates ubiquitin to UBA1 in the cytosol See in Reactome R-HSA-8852134 ( R-HSA-8866652 ) R-HSA-8852134 Reaction Name: UBA1 adenylates ubiquitin in the cytosol See in Reactome R-HSA-8852136 ( R-HSA-8866652 ) R-HSA-8852136 Reaction Name: UBA1 conjugates ubiquitin to UBA1 in the nucleus See in Reactome R-HSA-983152 ( R-HSA-983168 ) R-HSA-983152 Reaction Name: Transfer of ubiquitin from E1 to E2 See in Reactome R-HSA-983153 ( R-HSA-983168 ) R-HSA-983153 Reaction Name: E1 mediated ubiquitin activation See in Reactome
MONDO:0026777	UBA1	P22314	6.2.1.45	R-HSA-8866652 R-HSA-8866652 Reactome Name: Synthesis of active ubiquitin: roles of E1 and E2 enzymes See in Reactome R-HSA-983168 R-HSA-983168 Reactome Name: Antigen processing: Ubiquitination & Proteasome degradation See in Reactome	R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-983169 R-HSA-983169 Reactome Name: Class I MHC mediated antigen processing & presentation See in Reactome R-HSA-8852135 R-HSA-8852135 Reactome Name: Protein ubiquitination See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome R-HSA-1280218 R-HSA-1280218 Reactome Name: Adaptive Immune System See in Reactome	Immune System Metabolism of proteins	R-HSA-8852128 ( R-HSA-8866652 ) R-HSA-8852128 Reaction Name: UBA1 adenylates ubiquitin in the nucleoplasm See in Reactome R-HSA-8852129 ( R-HSA-8866652 ) R-HSA-8852129 Reaction Name: UBA1 conjugates ubiquitin to cytosolic E2 enzymes See in Reactome R-HSA-8852130 ( R-HSA-8866652 ) R-HSA-8852130 Reaction Name: UBA1 conjugates ubiquitin to nuclear E2 enzymes See in Reactome R-HSA-8852131 ( R-HSA-8866652 ) R-HSA-8852131 Reaction Name: Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus See in Reactome R-HSA-8852132 ( R-HSA-8866652 ) R-HSA-8852132 Reaction Name: Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol See in Reactome R-HSA-8852133 ( R-HSA-8866652 ) R-HSA-8852133 Reaction Name: UBA1 conjugates ubiquitin to UBA1 in the cytosol See in Reactome R-HSA-8852134 ( R-HSA-8866652 ) R-HSA-8852134 Reaction Name: UBA1 adenylates ubiquitin in the cytosol See in Reactome R-HSA-8852136 ( R-HSA-8866652 ) R-HSA-8852136 Reaction Name: UBA1 conjugates ubiquitin to UBA1 in the nucleus See in Reactome R-HSA-983152 ( R-HSA-983168 ) R-HSA-983152 Reaction Name: Transfer of ubiquitin from E1 to E2 See in Reactome R-HSA-983153 ( R-HSA-983168 ) R-HSA-983153 Reaction Name: E1 mediated ubiquitin activation See in Reactome