DAR - Bologna Biocomputing Group

Search summary (EC number: 5.2.1.8)

Number of enzymes:	4
Number of disease:	9
Number of reactomes:	3
Number of reactions:	11

Search results (EC number: 5.2.1.8)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0008147	PPIB	P23284	5.2.1.8	R-HSA-1650814 R-HSA-1650814 Reactome Name: Collagen biosynthesis and modifying enzymes See in Reactome	R-HSA-1474244 R-HSA-1474244 Reactome Name: Extracellular matrix organization See in Reactome R-HSA-1474290 R-HSA-1474290 Reactome Name: Collagen formation See in Reactome	Extracellular matrix organization	R-HSA-1980233 ( R-HSA-1650814 ) R-HSA-1980233 Reaction Name: Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen See in Reactome R-HSA-2022073 ( R-HSA-1650814 ) R-HSA-2022073 Reaction Name: Procollagen triple helix formation See in Reactome R-HSA-8948226 ( R-HSA-1650814 ) R-HSA-8948226 Reaction Name: Prolyl 3-hydroxylases:Fe2+:3,4-Hyp collagen propeptides dissociates See in Reactome R-HSA-8948230 ( R-HSA-1650814 ) R-HSA-8948230 Reaction Name: P3HB binds 4-Hyp-collagen propeptides See in Reactome
MONDO:0008148	PPIB	P23284	5.2.1.8	R-HSA-1650814 R-HSA-1650814 Reactome Name: Collagen biosynthesis and modifying enzymes See in Reactome	R-HSA-1474244 R-HSA-1474244 Reactome Name: Extracellular matrix organization See in Reactome R-HSA-1474290 R-HSA-1474290 Reactome Name: Collagen formation See in Reactome	Extracellular matrix organization	R-HSA-1980233 ( R-HSA-1650814 ) R-HSA-1980233 Reaction Name: Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen See in Reactome R-HSA-2022073 ( R-HSA-1650814 ) R-HSA-2022073 Reaction Name: Procollagen triple helix formation See in Reactome R-HSA-8948226 ( R-HSA-1650814 ) R-HSA-8948226 Reaction Name: Prolyl 3-hydroxylases:Fe2+:3,4-Hyp collagen propeptides dissociates See in Reactome R-HSA-8948230 ( R-HSA-1650814 ) R-HSA-8948230 Reaction Name: P3HB binds 4-Hyp-collagen propeptides See in Reactome
MONDO:0008148	FKBP10	Q96AY3	5.2.1.8
MONDO:0009804	PPIB	P23284	5.2.1.8	R-HSA-1650814 R-HSA-1650814 Reactome Name: Collagen biosynthesis and modifying enzymes See in Reactome	R-HSA-1474244 R-HSA-1474244 Reactome Name: Extracellular matrix organization See in Reactome R-HSA-1474290 R-HSA-1474290 Reactome Name: Collagen formation See in Reactome	Extracellular matrix organization	R-HSA-1980233 ( R-HSA-1650814 ) R-HSA-1980233 Reaction Name: Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen See in Reactome R-HSA-2022073 ( R-HSA-1650814 ) R-HSA-2022073 Reaction Name: Procollagen triple helix formation See in Reactome R-HSA-8948226 ( R-HSA-1650814 ) R-HSA-8948226 Reaction Name: Prolyl 3-hydroxylases:Fe2+:3,4-Hyp collagen propeptides dissociates See in Reactome R-HSA-8948230 ( R-HSA-1650814 ) R-HSA-8948230 Reaction Name: P3HB binds 4-Hyp-collagen propeptides See in Reactome
MONDO:0009804	FKBP10	Q96AY3	5.2.1.8
MONDO:0009805	PPIB	P23284	5.2.1.8	R-HSA-1650814 R-HSA-1650814 Reactome Name: Collagen biosynthesis and modifying enzymes See in Reactome	R-HSA-1474244 R-HSA-1474244 Reactome Name: Extracellular matrix organization See in Reactome R-HSA-1474290 R-HSA-1474290 Reactome Name: Collagen formation See in Reactome	Extracellular matrix organization	R-HSA-1980233 ( R-HSA-1650814 ) R-HSA-1980233 Reaction Name: Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen See in Reactome R-HSA-2022073 ( R-HSA-1650814 ) R-HSA-2022073 Reaction Name: Procollagen triple helix formation See in Reactome R-HSA-8948226 ( R-HSA-1650814 ) R-HSA-8948226 Reaction Name: Prolyl 3-hydroxylases:Fe2+:3,4-Hyp collagen propeptides dissociates See in Reactome R-HSA-8948230 ( R-HSA-1650814 ) R-HSA-8948230 Reaction Name: P3HB binds 4-Hyp-collagen propeptides See in Reactome
MONDO:0009806	FKBP10	Q96AY3	5.2.1.8
MONDO:0012592	FKBP10	Q96AY3	5.2.1.8
MONDO:0013800	FKBP14	Q9NWM8	5.2.1.8	R-HSA-381038 R-HSA-381038 Reactome Name: XBP1(S) activates chaperone genes See in Reactome	R-HSA-381070 R-HSA-381070 Reactome Name: IRE1alpha activates chaperones See in Reactome R-HSA-381119 R-HSA-381119 Reactome Name: Unfolded Protein Response (UPR) See in Reactome R-HSA-8953897 R-HSA-8953897 Reactome Name: Cellular responses to stimuli See in Reactome R-HSA-2262752 R-HSA-2262752 Reactome Name: Cellular responses to stress See in Reactome	Cellular responses to stimuli	R-HSA-1791114 ( R-HSA-381038 ) R-HSA-1791114 Reaction Name: Expression of FKBP14 See in Reactome
MONDO:0015241	FKBP10	Q96AY3	5.2.1.8
MONDO:0030258	PPIL1	Q9Y3C6	5.2.1.8	R-HSA-72163 R-HSA-72163 Reactome Name: mRNA Splicing - Major Pathway See in Reactome	R-HSA-8953854 R-HSA-8953854 Reactome Name: Metabolism of RNA See in Reactome R-HSA-72203 R-HSA-72203 Reactome Name: Processing of Capped Intron-Containing Pre-mRNA See in Reactome R-HSA-72172 R-HSA-72172 Reactome Name: mRNA Splicing See in Reactome	Metabolism of RNA	R-HSA-156661 ( R-HSA-72163 ) R-HSA-156661 Reaction Name: Formation of Exon Junction Complex See in Reactome R-HSA-72127 ( R-HSA-72163 ) R-HSA-72127 Reaction Name: Formation of the Spliceosomal B Complex See in Reactome R-HSA-72130 ( R-HSA-72163 ) R-HSA-72130 Reaction Name: Formation of an intermediate Spliceosomal C complex See in Reactome R-HSA-72139 ( R-HSA-72163 ) R-HSA-72139 Reaction Name: Formation of the active Spliceosomal C complex See in Reactome R-HSA-72143 ( R-HSA-72163 ) R-HSA-72143 Reaction Name: Lariat Formation and 5'-Splice Site Cleavage See in Reactome R-HSA-72160 ( R-HSA-72163 ) R-HSA-72160 Reaction Name: Cleavage at the 3'-Splice Site and Exon Ligation See in Reactome