DAR - Bologna Biocomputing Group

Search summary (EC number: 4.1.1.32)

Number of enzymes:	2
Number of disease:	2
Number of reactomes:	4
Number of reactions:	5

Search results (EC number: 4.1.1.32)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0009864	PCK2	Q16822	4.1.1.32	R-HSA-70263 R-HSA-70263 Reactome Name: Gluconeogenesis See in Reactome	R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-70326 R-HSA-70326 Reactome Name: Glucose metabolism See in Reactome R-HSA-71387 R-HSA-71387 Reactome Name: Metabolism of carbohydrates See in Reactome	Metabolism	R-HSA-372819 ( R-HSA-70263 ) R-HSA-372819 Reaction Name: oxaloacetate + GTP => phosphoenolpyruvate + GDP + CO2 [mitochondrial matrix] See in Reactome
MONDO:0009866	PCK1	P35558	4.1.1.32 2.7.11.-	R-HSA-70263 R-HSA-70263 Reactome Name: Gluconeogenesis See in Reactome R-HSA-9615017 R-HSA-9615017 Reactome Name: FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes See in Reactome R-HSA-381340 R-HSA-381340 Reactome Name: Transcriptional regulation of white adipocyte differentiation See in Reactome R-HSA-9632974 R-HSA-9632974 Reactome Name: NR1H2 & NR1H3 regulate gene expression linked to gluconeogenesis See in Reactome	R-HSA-70326 R-HSA-70326 Reactome Name: Glucose metabolism See in Reactome R-HSA-9006931 R-HSA-9006931 Reactome Name: Signaling by Nuclear Receptors See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-71387 R-HSA-71387 Reactome Name: Metabolism of carbohydrates See in Reactome R-HSA-9614085 R-HSA-9614085 Reactome Name: FOXO-mediated transcription See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-9024446 R-HSA-9024446 Reactome Name: NR1H2 and NR1H3-mediated signaling See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome	Gene expression (Transcription) Metabolism Signal Transduction Developmental Biology	R-HSA-560472 ( R-HSA-381340 ) R-HSA-560472 Reaction Name: Expression of Phosphoenolpyruvate carboxykinase 1 (PEPCK-C) See in Reactome R-HSA-70241 ( R-HSA-70263 ) R-HSA-70241 Reaction Name: oxaloacetate + GTP => phosphoenolpyruvate + GDP + CO2 [cytosol] See in Reactome R-HSA-9605051 ( R-HSA-9632974 ) R-HSA-9605051 Reaction Name: Expression of PCK1 regulated by NR1H3 See in Reactome R-HSA-9623280 ( R-HSA-9615017 ) R-HSA-9623280 Reaction Name: PCK1 gene expression is stimulated by FOXO1:PPARGC1A See in Reactome