DAR - Bologna Biocomputing Group

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0014827	CAPN1	P07384	3.4.22.52	R-HSA-6798695 R-HSA-6798695 Reactome Name: Neutrophil degranulation See in Reactome R-HSA-1474228 R-HSA-1474228 Reactome Name: Degradation of the extracellular matrix See in Reactome R-HSA-6809371 R-HSA-6809371 Reactome Name: Formation of the cornified envelope See in Reactome	R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-1474244 R-HSA-1474244 Reactome Name: Extracellular matrix organization See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-6805567 R-HSA-6805567 Reactome Name: Keratinization See in Reactome	Extracellular matrix organization Immune System Developmental Biology	R-HSA-2534260 ( R-HSA-1474228 ) R-HSA-2534260 Reaction Name: E-cadherin degradation by caspase-3 and calpain-1 See in Reactome R-HSA-6800434 ( R-HSA-6798695 ) R-HSA-6800434 Reaction Name: Exocytosis of ficolin-rich granule lumen proteins See in Reactome R-HSA-8848658 ( R-HSA-1474228 ) R-HSA-8848658 Reaction Name: CAPN:4xCa2+:CAPNS cleave cytoskeletal proteins See in Reactome R-HSA-8934819 ( R-HSA-6809371 ) R-HSA-8934819 Reaction Name: Cytoplasmic proteases cleave Profilaggrin producing Filaggrin See in Reactome