DAR - Bologna Biocomputing Group

Search summary (EC number: 3.4.21.71)

Number of enzymes:	1
Number of disease:	5
Number of reactomes:	1
Number of reactions:	2

Search results (EC number: 3.4.21.71)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0005010	CELA2A	P08217	3.4.21.71	R-HSA-6809371 R-HSA-6809371 Reactome Name: Formation of the cornified envelope See in Reactome	R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-6805567 R-HSA-6805567 Reactome Name: Keratinization See in Reactome	Developmental Biology	R-HSA-8849857 ( R-HSA-6809371 ) R-HSA-8849857 Reaction Name: KLK5 cleaves and activates CELA2 See in Reactome R-HSA-8934819 ( R-HSA-6809371 ) R-HSA-8934819 Reaction Name: Cytoplasmic proteases cleave Profilaggrin producing Filaggrin See in Reactome
MONDO:0005044	CELA2A	P08217	3.4.21.71	R-HSA-6809371 R-HSA-6809371 Reactome Name: Formation of the cornified envelope See in Reactome	R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-6805567 R-HSA-6805567 Reactome Name: Keratinization See in Reactome	Developmental Biology	R-HSA-8849857 ( R-HSA-6809371 ) R-HSA-8849857 Reaction Name: KLK5 cleaves and activates CELA2 See in Reactome R-HSA-8934819 ( R-HSA-6809371 ) R-HSA-8934819 Reaction Name: Cytoplasmic proteases cleave Profilaggrin producing Filaggrin See in Reactome
MONDO:0005347	CELA2A	P08217	3.4.21.71	R-HSA-6809371 R-HSA-6809371 Reactome Name: Formation of the cornified envelope See in Reactome	R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-6805567 R-HSA-6805567 Reactome Name: Keratinization See in Reactome	Developmental Biology	R-HSA-8849857 ( R-HSA-6809371 ) R-HSA-8849857 Reaction Name: KLK5 cleaves and activates CELA2 See in Reactome R-HSA-8934819 ( R-HSA-6809371 ) R-HSA-8934819 Reaction Name: Cytoplasmic proteases cleave Profilaggrin producing Filaggrin See in Reactome
MONDO:0014431	CELA2A	P08217	3.4.21.71	R-HSA-6809371 R-HSA-6809371 Reactome Name: Formation of the cornified envelope See in Reactome	R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-6805567 R-HSA-6805567 Reactome Name: Keratinization See in Reactome	Developmental Biology	R-HSA-8849857 ( R-HSA-6809371 ) R-HSA-8849857 Reaction Name: KLK5 cleaves and activates CELA2 See in Reactome R-HSA-8934819 ( R-HSA-6809371 ) R-HSA-8934819 Reaction Name: Cytoplasmic proteases cleave Profilaggrin producing Filaggrin See in Reactome
MONDO:0032837	CELA2A	P08217	3.4.21.71	R-HSA-6809371 R-HSA-6809371 Reactome Name: Formation of the cornified envelope See in Reactome	R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-6805567 R-HSA-6805567 Reactome Name: Keratinization See in Reactome	Developmental Biology	R-HSA-8849857 ( R-HSA-6809371 ) R-HSA-8849857 Reaction Name: KLK5 cleaves and activates CELA2 See in Reactome R-HSA-8934819 ( R-HSA-6809371 ) R-HSA-8934819 Reaction Name: Cytoplasmic proteases cleave Profilaggrin producing Filaggrin See in Reactome