DAR - Bologna Biocomputing Group

Search summary (EC number: 3.4.21.21)

Number of enzymes:	1
Number of disease:	1
Number of reactomes:	5
Number of reactions:	11

Search results (EC number: 3.4.21.21)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0009211	F7	P08709	3.4.21.21	R-HSA-159740 R-HSA-159740 Reactome Name: Gamma-carboxylation of protein precursors See in Reactome R-HSA-140834 R-HSA-140834 Reactome Name: Extrinsic Pathway of Fibrin Clot Formation See in Reactome R-HSA-1368108 R-HSA-1368108 Reactome Name: BMAL1:CLOCK,NPAS2 activates circadian gene expression See in Reactome R-HSA-159763 R-HSA-159763 Reactome Name: Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus See in Reactome R-HSA-159782 R-HSA-159782 Reactome Name: Removal of aminoterminal propeptides from gamma-carboxylated proteins See in Reactome	R-HSA-400253 R-HSA-400253 Reactome Name: Circadian Clock See in Reactome R-HSA-163841 R-HSA-163841 Reactome Name: Gamma carboxylation, hypusine formation and arylsulfatase activation See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-159854 R-HSA-159854 Reactome Name: Gamma-carboxylation, transport, and amino-terminal cleavage of proteins See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome R-HSA-140877 R-HSA-140877 Reactome Name: Formation of Fibrin Clot (Clotting Cascade) See in Reactome R-HSA-109582 R-HSA-109582 Reactome Name: Hemostasis See in Reactome	Circadian Clock Metabolism of proteins Hemostasis	R-HSA-140736 ( R-HSA-140834 ) R-HSA-140736 Reaction Name: factor X -> factor Xa + factor X activation peptide (TF:F7a catalyst) See in Reactome R-HSA-140748 ( R-HSA-140834 ) R-HSA-140748 Reaction Name: tissue factor (TF) + activated factor VII (F7a) -> TF:F7a complex See in Reactome R-HSA-140769 ( R-HSA-140834 ) R-HSA-140769 Reaction Name: factor VII -> factor VIIa See in Reactome R-HSA-140777 ( R-HSA-140834 ) R-HSA-140777 Reaction Name: factor X -> factor Xa + factor X activation peptide (TF:F7 catalyst) See in Reactome R-HSA-140783 ( R-HSA-140834 ) R-HSA-140783 Reaction Name: tissue factor (TF) + factor VII (F7) -> TF:F7 complex See in Reactome R-HSA-140823 ( R-HSA-140834 ) R-HSA-140823 Reaction Name: factor IX -> factor IXa + factor IX activation peptide (TF:F7a catalyst) See in Reactome R-HSA-140825 ( R-HSA-140834 ) R-HSA-140825 Reaction Name: TFPI + TF:F7a + factor Xa -> TFPI:TF:F7a:factor Xa See in Reactome R-HSA-159761 ( R-HSA-159740 ) R-HSA-159761 Reaction Name: GGCX gamma-carboxylates F7(21-466) (pro-factor VII) See in Reactome R-HSA-159783 ( R-HSA-159763 ) R-HSA-159783 Reaction Name: Gamma-carboxy pro-factor VII transport from the endoplasmic reticulum to the Golgi apparatus See in Reactome R-HSA-159868 ( R-HSA-159782 ) R-HSA-159868 Reaction Name: Furin cleaves pro-factor VII to factor VII See in Reactome R-HSA-549428 ( R-HSA-1368108 ) R-HSA-549428 Reaction Name: Expression of FACTOR VII (F7) See in Reactome