DAR - Bologna Biocomputing Group

Search summary (EC number: 3.4.14.1)

Number of enzymes:	1
Number of disease:	3
Number of reactomes:	4
Number of reactions:	15

Search results (EC number: 3.4.14.1)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0008226	CTSC	P53634	3.4.14.1	R-HSA-6798695 R-HSA-6798695 Reactome Name: Neutrophil degranulation See in Reactome R-HSA-5694530 R-HSA-5694530 Reactome Name: Cargo concentration in the ER See in Reactome R-HSA-204005 R-HSA-204005 Reactome Name: COPII-mediated vesicle transport See in Reactome R-HSA-2132295 R-HSA-2132295 Reactome Name: MHC class II antigen presentation See in Reactome	R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-199991 R-HSA-199991 Reactome Name: Membrane Trafficking See in Reactome R-HSA-446203 R-HSA-446203 Reactome Name: Asparagine N-linked glycosylation See in Reactome R-HSA-199977 R-HSA-199977 Reactome Name: ER to Golgi Anterograde Transport See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome R-HSA-948021 R-HSA-948021 Reactome Name: Transport to the Golgi and subsequent modification See in Reactome R-HSA-1280218 R-HSA-1280218 Reactome Name: Adaptive Immune System See in Reactome R-HSA-5653656 R-HSA-5653656 Reactome Name: Vesicle-mediated transport See in Reactome	Immune System Metabolism of proteins Vesicle-mediated transport	R-HSA-203973 ( R-HSA-204005 ) R-HSA-203973 Reaction Name: Vesicle budding See in Reactome R-HSA-204008 ( R-HSA-204005 ) R-HSA-204008 Reaction Name: SEC31:SEC13 and v-SNARE recruitment See in Reactome R-HSA-2130349 ( R-HSA-2132295 ) R-HSA-2130349 Reaction Name: Generation of CLIP from lip10 See in Reactome R-HSA-2130504 ( R-HSA-2132295 ) R-HSA-2130504 Reaction Name: Cleavage of lip22 to lip10 See in Reactome R-HSA-2130706 ( R-HSA-2132295 ) R-HSA-2130706 Reaction Name: MHC class II antigen processing See in Reactome R-HSA-5694409 ( R-HSA-204005 ) R-HSA-5694409 Reaction Name: Nucleotide exchange on RAB1 See in Reactome R-HSA-5694417 ( R-HSA-204005 ) R-HSA-5694417 Reaction Name: SEC16 complex binds SAR1B:GTP:SEC23:SEC24 See in Reactome R-HSA-5694418 ( R-HSA-204005 ) R-HSA-5694418 Reaction Name: RAB1:GTP binds USO1 and GORASP1:GOLGA2 See in Reactome R-HSA-5694428 ( R-HSA-5694530 ) R-HSA-5694428 Reaction Name: LMAN family proteins bind glycosylated cargo See in Reactome R-HSA-5694439 ( R-HSA-204005 ) R-HSA-5694439 Reaction Name: COPII coat binds TRAPPCII and RAB1:GDP See in Reactome R-HSA-5694441 ( R-HSA-204005 ) R-HSA-5694441 Reaction Name: CSNK1D phosphorylates SEC23 See in Reactome R-HSA-5694446 ( R-HSA-204005 ) R-HSA-5694446 Reaction Name: BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle See in Reactome R-HSA-5694522 ( R-HSA-204005; R-HSA-5694530 ) R-HSA-5694522 Reaction Name: Inner coat assembly and cargo binding See in Reactome R-HSA-5694527 ( R-HSA-204005 ) R-HSA-5694527 Reaction Name: Loss of SAR1B GTPase See in Reactome R-HSA-6798751 ( R-HSA-6798695 ) R-HSA-6798751 Reaction Name: Exocytosis of azurophil granule lumen proteins See in Reactome
MONDO:0009490	CTSC	P53634	3.4.14.1	R-HSA-6798695 R-HSA-6798695 Reactome Name: Neutrophil degranulation See in Reactome R-HSA-5694530 R-HSA-5694530 Reactome Name: Cargo concentration in the ER See in Reactome R-HSA-204005 R-HSA-204005 Reactome Name: COPII-mediated vesicle transport See in Reactome R-HSA-2132295 R-HSA-2132295 Reactome Name: MHC class II antigen presentation See in Reactome	R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-199991 R-HSA-199991 Reactome Name: Membrane Trafficking See in Reactome R-HSA-446203 R-HSA-446203 Reactome Name: Asparagine N-linked glycosylation See in Reactome R-HSA-199977 R-HSA-199977 Reactome Name: ER to Golgi Anterograde Transport See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome R-HSA-948021 R-HSA-948021 Reactome Name: Transport to the Golgi and subsequent modification See in Reactome R-HSA-1280218 R-HSA-1280218 Reactome Name: Adaptive Immune System See in Reactome R-HSA-5653656 R-HSA-5653656 Reactome Name: Vesicle-mediated transport See in Reactome	Immune System Metabolism of proteins Vesicle-mediated transport	R-HSA-203973 ( R-HSA-204005 ) R-HSA-203973 Reaction Name: Vesicle budding See in Reactome R-HSA-204008 ( R-HSA-204005 ) R-HSA-204008 Reaction Name: SEC31:SEC13 and v-SNARE recruitment See in Reactome R-HSA-2130349 ( R-HSA-2132295 ) R-HSA-2130349 Reaction Name: Generation of CLIP from lip10 See in Reactome R-HSA-2130504 ( R-HSA-2132295 ) R-HSA-2130504 Reaction Name: Cleavage of lip22 to lip10 See in Reactome R-HSA-2130706 ( R-HSA-2132295 ) R-HSA-2130706 Reaction Name: MHC class II antigen processing See in Reactome R-HSA-5694409 ( R-HSA-204005 ) R-HSA-5694409 Reaction Name: Nucleotide exchange on RAB1 See in Reactome R-HSA-5694417 ( R-HSA-204005 ) R-HSA-5694417 Reaction Name: SEC16 complex binds SAR1B:GTP:SEC23:SEC24 See in Reactome R-HSA-5694418 ( R-HSA-204005 ) R-HSA-5694418 Reaction Name: RAB1:GTP binds USO1 and GORASP1:GOLGA2 See in Reactome R-HSA-5694428 ( R-HSA-5694530 ) R-HSA-5694428 Reaction Name: LMAN family proteins bind glycosylated cargo See in Reactome R-HSA-5694439 ( R-HSA-204005 ) R-HSA-5694439 Reaction Name: COPII coat binds TRAPPCII and RAB1:GDP See in Reactome R-HSA-5694441 ( R-HSA-204005 ) R-HSA-5694441 Reaction Name: CSNK1D phosphorylates SEC23 See in Reactome R-HSA-5694446 ( R-HSA-204005 ) R-HSA-5694446 Reaction Name: BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle See in Reactome R-HSA-5694522 ( R-HSA-204005; R-HSA-5694530 ) R-HSA-5694522 Reaction Name: Inner coat assembly and cargo binding See in Reactome R-HSA-5694527 ( R-HSA-204005 ) R-HSA-5694527 Reaction Name: Loss of SAR1B GTPase See in Reactome R-HSA-6798751 ( R-HSA-6798695 ) R-HSA-6798751 Reaction Name: Exocytosis of azurophil granule lumen proteins See in Reactome
MONDO:0009491	CTSC	P53634	3.4.14.1	R-HSA-6798695 R-HSA-6798695 Reactome Name: Neutrophil degranulation See in Reactome R-HSA-5694530 R-HSA-5694530 Reactome Name: Cargo concentration in the ER See in Reactome R-HSA-204005 R-HSA-204005 Reactome Name: COPII-mediated vesicle transport See in Reactome R-HSA-2132295 R-HSA-2132295 Reactome Name: MHC class II antigen presentation See in Reactome	R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-199991 R-HSA-199991 Reactome Name: Membrane Trafficking See in Reactome R-HSA-446203 R-HSA-446203 Reactome Name: Asparagine N-linked glycosylation See in Reactome R-HSA-199977 R-HSA-199977 Reactome Name: ER to Golgi Anterograde Transport See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome R-HSA-948021 R-HSA-948021 Reactome Name: Transport to the Golgi and subsequent modification See in Reactome R-HSA-1280218 R-HSA-1280218 Reactome Name: Adaptive Immune System See in Reactome R-HSA-5653656 R-HSA-5653656 Reactome Name: Vesicle-mediated transport See in Reactome	Immune System Metabolism of proteins Vesicle-mediated transport	R-HSA-203973 ( R-HSA-204005 ) R-HSA-203973 Reaction Name: Vesicle budding See in Reactome R-HSA-204008 ( R-HSA-204005 ) R-HSA-204008 Reaction Name: SEC31:SEC13 and v-SNARE recruitment See in Reactome R-HSA-2130349 ( R-HSA-2132295 ) R-HSA-2130349 Reaction Name: Generation of CLIP from lip10 See in Reactome R-HSA-2130504 ( R-HSA-2132295 ) R-HSA-2130504 Reaction Name: Cleavage of lip22 to lip10 See in Reactome R-HSA-2130706 ( R-HSA-2132295 ) R-HSA-2130706 Reaction Name: MHC class II antigen processing See in Reactome R-HSA-5694409 ( R-HSA-204005 ) R-HSA-5694409 Reaction Name: Nucleotide exchange on RAB1 See in Reactome R-HSA-5694417 ( R-HSA-204005 ) R-HSA-5694417 Reaction Name: SEC16 complex binds SAR1B:GTP:SEC23:SEC24 See in Reactome R-HSA-5694418 ( R-HSA-204005 ) R-HSA-5694418 Reaction Name: RAB1:GTP binds USO1 and GORASP1:GOLGA2 See in Reactome R-HSA-5694428 ( R-HSA-5694530 ) R-HSA-5694428 Reaction Name: LMAN family proteins bind glycosylated cargo See in Reactome R-HSA-5694439 ( R-HSA-204005 ) R-HSA-5694439 Reaction Name: COPII coat binds TRAPPCII and RAB1:GDP See in Reactome R-HSA-5694441 ( R-HSA-204005 ) R-HSA-5694441 Reaction Name: CSNK1D phosphorylates SEC23 See in Reactome R-HSA-5694446 ( R-HSA-204005 ) R-HSA-5694446 Reaction Name: BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle See in Reactome R-HSA-5694522 ( R-HSA-204005; R-HSA-5694530 ) R-HSA-5694522 Reaction Name: Inner coat assembly and cargo binding See in Reactome R-HSA-5694527 ( R-HSA-204005 ) R-HSA-5694527 Reaction Name: Loss of SAR1B GTPase See in Reactome R-HSA-6798751 ( R-HSA-6798695 ) R-HSA-6798751 Reaction Name: Exocytosis of azurophil granule lumen proteins See in Reactome