DAR - Bologna Biocomputing Group

Search summary (EC number: 3.2.1.45)

Number of enzymes:	2
Number of disease:	10
Number of reactomes:	2
Number of reactions:	3

Search results (EC number: 3.2.1.45)

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DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0002049	GBA	P04062	3.2.1.- 2.4.1.- 3.2.1.45	R-HSA-390471 R-HSA-390471 Reactome Name: Association of TriC/CCT with target proteins during biosynthesis See in Reactome R-HSA-1660662 R-HSA-1660662 Reactome Name: Glycosphingolipid metabolism See in Reactome	R-HSA-391251 R-HSA-391251 Reactome Name: Protein folding See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-428157 R-HSA-428157 Reactome Name: Sphingolipid metabolism See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-390466 R-HSA-390466 Reactome Name: Chaperonin-mediated protein folding See in Reactome	Metabolism of proteins Metabolism	R-HSA-1605591 ( R-HSA-1660662 ) R-HSA-1605591 Reaction Name: Glucosylceramidase cleaves the glucosidic bond of glucocerebroside to form ceramide See in Reactome R-HSA-390470 ( R-HSA-390471 ) R-HSA-390470 Reaction Name: Association of CCT/TriC with other substrates during biosynthesis (unknown chaperone) See in Reactome
MONDO:0007488	GBA	P04062	3.2.1.- 2.4.1.- 3.2.1.45	R-HSA-390471 R-HSA-390471 Reactome Name: Association of TriC/CCT with target proteins during biosynthesis See in Reactome R-HSA-1660662 R-HSA-1660662 Reactome Name: Glycosphingolipid metabolism See in Reactome	R-HSA-391251 R-HSA-391251 Reactome Name: Protein folding See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-428157 R-HSA-428157 Reactome Name: Sphingolipid metabolism See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-390466 R-HSA-390466 Reactome Name: Chaperonin-mediated protein folding See in Reactome	Metabolism of proteins Metabolism	R-HSA-1605591 ( R-HSA-1660662 ) R-HSA-1605591 Reaction Name: Glucosylceramidase cleaves the glucosidic bond of glucocerebroside to form ceramide See in Reactome R-HSA-390470 ( R-HSA-390471 ) R-HSA-390470 Reaction Name: Association of CCT/TriC with other substrates during biosynthesis (unknown chaperone) See in Reactome
MONDO:0008199	GBA	P04062	3.2.1.- 2.4.1.- 3.2.1.45	R-HSA-390471 R-HSA-390471 Reactome Name: Association of TriC/CCT with target proteins during biosynthesis See in Reactome R-HSA-1660662 R-HSA-1660662 Reactome Name: Glycosphingolipid metabolism See in Reactome	R-HSA-391251 R-HSA-391251 Reactome Name: Protein folding See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-428157 R-HSA-428157 Reactome Name: Sphingolipid metabolism See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-390466 R-HSA-390466 Reactome Name: Chaperonin-mediated protein folding See in Reactome	Metabolism of proteins Metabolism	R-HSA-1605591 ( R-HSA-1660662 ) R-HSA-1605591 Reaction Name: Glucosylceramidase cleaves the glucosidic bond of glucocerebroside to form ceramide See in Reactome R-HSA-390470 ( R-HSA-390471 ) R-HSA-390470 Reaction Name: Association of CCT/TriC with other substrates during biosynthesis (unknown chaperone) See in Reactome
MONDO:0009265	GBA	P04062	3.2.1.- 2.4.1.- 3.2.1.45	R-HSA-390471 R-HSA-390471 Reactome Name: Association of TriC/CCT with target proteins during biosynthesis See in Reactome R-HSA-1660662 R-HSA-1660662 Reactome Name: Glycosphingolipid metabolism See in Reactome	R-HSA-391251 R-HSA-391251 Reactome Name: Protein folding See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-428157 R-HSA-428157 Reactome Name: Sphingolipid metabolism See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-390466 R-HSA-390466 Reactome Name: Chaperonin-mediated protein folding See in Reactome	Metabolism of proteins Metabolism	R-HSA-1605591 ( R-HSA-1660662 ) R-HSA-1605591 Reaction Name: Glucosylceramidase cleaves the glucosidic bond of glucocerebroside to form ceramide See in Reactome R-HSA-390470 ( R-HSA-390471 ) R-HSA-390470 Reaction Name: Association of CCT/TriC with other substrates during biosynthesis (unknown chaperone) See in Reactome
MONDO:0009266	GBA	P04062	3.2.1.- 2.4.1.- 3.2.1.45	R-HSA-390471 R-HSA-390471 Reactome Name: Association of TriC/CCT with target proteins during biosynthesis See in Reactome R-HSA-1660662 R-HSA-1660662 Reactome Name: Glycosphingolipid metabolism See in Reactome	R-HSA-391251 R-HSA-391251 Reactome Name: Protein folding See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-428157 R-HSA-428157 Reactome Name: Sphingolipid metabolism See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-390466 R-HSA-390466 Reactome Name: Chaperonin-mediated protein folding See in Reactome	Metabolism of proteins Metabolism	R-HSA-1605591 ( R-HSA-1660662 ) R-HSA-1605591 Reaction Name: Glucosylceramidase cleaves the glucosidic bond of glucocerebroside to form ceramide See in Reactome R-HSA-390470 ( R-HSA-390471 ) R-HSA-390470 Reaction Name: Association of CCT/TriC with other substrates during biosynthesis (unknown chaperone) See in Reactome
MONDO:0009267	GBA	P04062	3.2.1.- 2.4.1.- 3.2.1.45	R-HSA-390471 R-HSA-390471 Reactome Name: Association of TriC/CCT with target proteins during biosynthesis See in Reactome R-HSA-1660662 R-HSA-1660662 Reactome Name: Glycosphingolipid metabolism See in Reactome	R-HSA-391251 R-HSA-391251 Reactome Name: Protein folding See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-428157 R-HSA-428157 Reactome Name: Sphingolipid metabolism See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-390466 R-HSA-390466 Reactome Name: Chaperonin-mediated protein folding See in Reactome	Metabolism of proteins Metabolism	R-HSA-1605591 ( R-HSA-1660662 ) R-HSA-1605591 Reaction Name: Glucosylceramidase cleaves the glucosidic bond of glucocerebroside to form ceramide See in Reactome R-HSA-390470 ( R-HSA-390471 ) R-HSA-390470 Reaction Name: Association of CCT/TriC with other substrates during biosynthesis (unknown chaperone) See in Reactome
MONDO:0009268	GBA	P04062	3.2.1.- 2.4.1.- 3.2.1.45	R-HSA-390471 R-HSA-390471 Reactome Name: Association of TriC/CCT with target proteins during biosynthesis See in Reactome R-HSA-1660662 R-HSA-1660662 Reactome Name: Glycosphingolipid metabolism See in Reactome	R-HSA-391251 R-HSA-391251 Reactome Name: Protein folding See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-428157 R-HSA-428157 Reactome Name: Sphingolipid metabolism See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-390466 R-HSA-390466 Reactome Name: Chaperonin-mediated protein folding See in Reactome	Metabolism of proteins Metabolism	R-HSA-1605591 ( R-HSA-1660662 ) R-HSA-1605591 Reaction Name: Glucosylceramidase cleaves the glucosidic bond of glucocerebroside to form ceramide See in Reactome R-HSA-390470 ( R-HSA-390471 ) R-HSA-390470 Reaction Name: Association of CCT/TriC with other substrates during biosynthesis (unknown chaperone) See in Reactome
MONDO:0011945	GBA	P04062	3.2.1.- 2.4.1.- 3.2.1.45	R-HSA-390471 R-HSA-390471 Reactome Name: Association of TriC/CCT with target proteins during biosynthesis See in Reactome R-HSA-1660662 R-HSA-1660662 Reactome Name: Glycosphingolipid metabolism See in Reactome	R-HSA-391251 R-HSA-391251 Reactome Name: Protein folding See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-428157 R-HSA-428157 Reactome Name: Sphingolipid metabolism See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-390466 R-HSA-390466 Reactome Name: Chaperonin-mediated protein folding See in Reactome	Metabolism of proteins Metabolism	R-HSA-1605591 ( R-HSA-1660662 ) R-HSA-1605591 Reaction Name: Glucosylceramidase cleaves the glucosidic bond of glucocerebroside to form ceramide See in Reactome R-HSA-390470 ( R-HSA-390471 ) R-HSA-390470 Reaction Name: Association of CCT/TriC with other substrates during biosynthesis (unknown chaperone) See in Reactome
MONDO:0013737	GBA2	Q9HCG7	3.2.1.- 2.4.1.- 3.2.1.45	R-HSA-1660662 R-HSA-1660662 Reactome Name: Glycosphingolipid metabolism See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-428157 R-HSA-428157 Reactome Name: Sphingolipid metabolism See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome	Metabolism	R-HSA-1861788 ( R-HSA-1660662 ) R-HSA-1861788 Reaction Name: Glucosylceramidase 2 cleaves the glucosidic bond of glucocerebroside to form ceramide (plasma membrane) See in Reactome
MONDO:0018129	GBA2	Q9HCG7	3.2.1.- 2.4.1.- 3.2.1.45	R-HSA-1660662 R-HSA-1660662 Reactome Name: Glycosphingolipid metabolism See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-428157 R-HSA-428157 Reactome Name: Sphingolipid metabolism See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome	Metabolism	R-HSA-1861788 ( R-HSA-1660662 ) R-HSA-1861788 Reaction Name: Glucosylceramidase 2 cleaves the glucosidic bond of glucocerebroside to form ceramide (plasma membrane) See in Reactome

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