DAR - Bologna Biocomputing Group

Search summary (EC number: 3.1.6.8)

Number of enzymes:	1
Number of disease:	3
Number of reactomes:	3
Number of reactions:	4

Search results (EC number: 3.1.6.8)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0010088	ARSA	P15289	3.1.6.8	R-HSA-6798695 R-HSA-6798695 Reactome Name: Neutrophil degranulation See in Reactome R-HSA-1660662 R-HSA-1660662 Reactome Name: Glycosphingolipid metabolism See in Reactome R-HSA-1663150 R-HSA-1663150 Reactome Name: The activation of arylsulfatases See in Reactome	R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-163841 R-HSA-163841 Reactome Name: Gamma carboxylation, hypusine formation and arylsulfatase activation See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-428157 R-HSA-428157 Reactome Name: Sphingolipid metabolism See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome	Immune System Metabolism of proteins Metabolism	R-HSA-1606807 ( R-HSA-1660662 ) R-HSA-1606807 Reaction Name: Arylsulfatase A hydrolyses sulfate from sulfatide to form cerebroside See in Reactome R-HSA-1614362 ( R-HSA-1660662; R-HSA-1663150 ) R-HSA-1614362 Reaction Name: SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases See in Reactome R-HSA-2248891 ( R-HSA-1660662 ) R-HSA-2248891 Reaction Name: Active ARSA translocates to the lysosome See in Reactome R-HSA-6798751 ( R-HSA-6798695 ) R-HSA-6798751 Reaction Name: Exocytosis of azurophil granule lumen proteins See in Reactome
MONDO:0017729	ARSA	P15289	3.1.6.8	R-HSA-6798695 R-HSA-6798695 Reactome Name: Neutrophil degranulation See in Reactome R-HSA-1660662 R-HSA-1660662 Reactome Name: Glycosphingolipid metabolism See in Reactome R-HSA-1663150 R-HSA-1663150 Reactome Name: The activation of arylsulfatases See in Reactome	R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-163841 R-HSA-163841 Reactome Name: Gamma carboxylation, hypusine formation and arylsulfatase activation See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-428157 R-HSA-428157 Reactome Name: Sphingolipid metabolism See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome	Immune System Metabolism of proteins Metabolism	R-HSA-1606807 ( R-HSA-1660662 ) R-HSA-1606807 Reaction Name: Arylsulfatase A hydrolyses sulfate from sulfatide to form cerebroside See in Reactome R-HSA-1614362 ( R-HSA-1660662; R-HSA-1663150 ) R-HSA-1614362 Reaction Name: SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases See in Reactome R-HSA-2248891 ( R-HSA-1660662 ) R-HSA-2248891 Reaction Name: Active ARSA translocates to the lysosome See in Reactome R-HSA-6798751 ( R-HSA-6798695 ) R-HSA-6798751 Reaction Name: Exocytosis of azurophil granule lumen proteins See in Reactome
MONDO:0017730	ARSA	P15289	3.1.6.8	R-HSA-6798695 R-HSA-6798695 Reactome Name: Neutrophil degranulation See in Reactome R-HSA-1660662 R-HSA-1660662 Reactome Name: Glycosphingolipid metabolism See in Reactome R-HSA-1663150 R-HSA-1663150 Reactome Name: The activation of arylsulfatases See in Reactome	R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-163841 R-HSA-163841 Reactome Name: Gamma carboxylation, hypusine formation and arylsulfatase activation See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-428157 R-HSA-428157 Reactome Name: Sphingolipid metabolism See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome	Immune System Metabolism of proteins Metabolism	R-HSA-1606807 ( R-HSA-1660662 ) R-HSA-1606807 Reaction Name: Arylsulfatase A hydrolyses sulfate from sulfatide to form cerebroside See in Reactome R-HSA-1614362 ( R-HSA-1660662; R-HSA-1663150 ) R-HSA-1614362 Reaction Name: SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases See in Reactome R-HSA-2248891 ( R-HSA-1660662 ) R-HSA-2248891 Reaction Name: Active ARSA translocates to the lysosome See in Reactome R-HSA-6798751 ( R-HSA-6798695 ) R-HSA-6798751 Reaction Name: Exocytosis of azurophil granule lumen proteins See in Reactome